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View the following Portsmouth Office Space listings, Office Condos and Office Buildings available for lease or rent. Other Portsmouth properties available for lease can be found by selecting a property type on the right.

30 Portsmouth Office Space listings for Lease found. For properties for Sale, try a new search above.

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Office for Lease - 100 Market Street
Office for Lease - 100 Market Street
Portsmouth, New Hampshire
100 Market Street offers a polished corporate image with state-of-the-art infrastructure, high-speed internet access, elegant lobby and common...
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4
$23.00
2,116 - 10,559 SF
54,000 SF
Office
Office Building
Office for Lease -
Office for Lease -
Portsmouth, New Hampshire
This is beautiful, contemporary, office space with unique high quality features. It offers incredible natural light from oversize arc windows...
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1
$20.00
5,121 SF
20,849 SF
Office
Office Building
Office for Lease - Sherburne House
Office for Lease - Sherburne House
Portsmouth, New Hampshire
Located in the heart of downtown is this magnificently restored Georgian recently occupied as a company office on three levels. 4569 square feet...
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1
$22.00
4,569 SF
4,569 SF
Office
Office Building
Office for Lease - Portsmouth Office Park
Office for Lease - Portsmouth Office Park
Portsmouth, New Hampshire
" 1,317 SF and 700 SF office units available for lease in Class A 50,000 SF office building in professional, well-maintained office park " New...
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1
$15.50
700 - 1,317 SF
50,000 SF
Office
Office Building
Office for Lease - 25 Maplewood Avenue
Office for Lease - 25 Maplewood Avenue
Portsmouth, New Hampshire
25 Maplewood Avenue is a 10,350 ± SF free standing office building located in the heart of downtown Portsmouth. This offering consists of 14...
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2
$20.00
4,000 - 6,350 SF
10,350 SF
Office
Office Building
Office for Lease - 290 Heritage Avenue
Office for Lease - 290 Heritage Avenue
Portsmouth, New Hampshire
Professional office space in this newly constructed building which offers all the efficiencies of new construction. A tenant has the ability to...
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1
$12.00
2,000 - 6,000 SF
6,000 SF
Office
Office Building
Office for Lease - 264 Lafayette Road, Unit B1B
Office for Lease - 264 Lafayette Road, Unit B1B
Portsmouth, New Hampshire
264 Lafayette Road, Unit B1B is a 1,515 ± square foot professional/medical office condominium at the Lafayette Professional Center in Portsmouth,...
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1
$15.00
1,515 SF
1,515 SF
Office
Office Building
Office for Lease -
Office for Lease -
Portsmouth, New Hampshire
This suite is located immediately off the elegant lobby of Two International Drive, a signature building positioned at the gateway to Pease...
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1
$25.00
2,948 SF
83,700 SF
Office
Office Building
Office for Lease -
Office for Lease -
Portsmouth, New Hampshire
2,200 ± SF of Class A office space is available at 755 Banfield Road. The available suite is located on the ground floor and consists of private...
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1
$12.00
2,200 SF
26,233 SF
Office
Office Building
Office for Lease - 111 Maplewood Avenue
Office for Lease - 111 Maplewood Avenue
Portsmouth, New Hampshire
3,100 ± SF of professional office space located at the north end of Portsmouth. This is a rare opportunity to lease space within walking distance...
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1
$22.00
3,100 SF
20,147 SF
Office
Office Building
Office for Lease - 110 Corporate Drive
Office for Lease - 110 Corporate Drive
Portsmouth, New Hampshire
The available space is 5,535 ± SF and has a mix of private offices, open area for cubicles and in-suite bathroom facilities. Ample on-site parking...
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1
$16.00
5,535 SF
75,301 SF
Office
Office Building
Office for Lease - Portsmouth, 210 Commerce Way
Office for Lease - Portsmouth, 210 Commerce Way
Portsmouth, New Hampshire
- 1,200 SF and 700 SF office units available for lease in Class A 50,000 SF office building in professional, well-maintained office park -...
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2
$16.50
700 - 1,200 SF
50,400 SF
Office
Office Building
Office for Lease - Seacoast Media Group
Office for Lease - Seacoast Media Group
Portsmouth, New Hampshire
Modern office suites on the second floor of the Seacoast Media Group building at the Pease International Tradeport. This well appointed and bright...
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1
$20.00
2,000 - 11,087 SF
74,134 SF
Office
Office Building
Office for Lease - Orchard Park Condos - Building A
Office for Lease - Orchard Park Condos - Building A
Portsmouth, New Hampshire
This 1,066 ± SF office space is located on the first floor of Building A. Perfect for all medical/professional office users.
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1
$16.50
1,066 SF
1,066 SF
Office
Office Building
Office for Lease - 767 Islington St. - Hideaways Plaza
Office for Lease - 767 Islington St. - Hideaways Plaza
Portsmouth, New Hampshire
Office/Retail Bldg. along the heavily trafficked Islington Street corridor in the hip West End of Portsmouth, NH. Easy access from major highways...
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2
$12.75 - $18.50
800 - 2,134 SF
16,000 SF
Office
Office Building
Office for Lease - 222 New Hampshire Ave
Office for Lease - 222 New Hampshire Ave
Portsmouth, New Hampshire
Located close to Interstate 95 and Route 33, this building totals over 62,000 square feet on two stories for mixed use (office, R&D, light...
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1
N/A
1,213 - 16,642 SF
84,000 SF
Office
Office Building
Office for Lease - Downtown Portsmouth, 51 Islington Street
Office for Lease - Downtown Portsmouth, 51 Islington Street
Portsmouth, New Hampshire
FOR SALE OR LEASE 1,325 SF & 1,135 SF of build-to-suit first floor office/retail space is available. This newly constructed...
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2
$25.00
1,135 - 1,325 SF
1,135 SF
Retail
Retail (Other)
Office for Lease - Waterfront Office Space at Riveredge
Office for Lease - Waterfront Office Space at Riveredge
Portsmouth, New Hampshire
Piscataqua River Waterfront Office. Conversion of the former Portsmouth Brewery building. Several options available within this unit situated...
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5
$29.09 - $100.00
180 - 1,650 SF
1,650 SF
Office
Office Building
Office for Lease -
Office for Lease -
Portsmouth, New Hampshire
The available space can accommodate many office/retail uses. It is ideal for medical users including dentists, opticians, physical therapists and...
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1
$14.00
893 - 3,500 SF
102,078 SF
Office
Office Building
Office for Lease -
Office for Lease -
Portsmouth, New Hampshire
This 12,390 +/- SF building is on two levels of 6,150 +/- SF with the second floor accessible by an elevator and two stairwells. The building is...
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$14.50
12,390 SF
12,390 SF
Office
Office Building
Office for Lease - 195 New Hampshire Ave
Office for Lease - 195 New Hampshire Ave
Portsmouth, New Hampshire
195 New Hampshire Ave is located on the corner of International Dr and New Hampshire Avenue. The building features an attractive facade with...
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1
N/A
3,557 - 9,213 SF
82,741 SF
Office
Office Building
Office for Lease - 1 New Hampshire Ave
Office for Lease - 1 New Hampshire Ave
Portsmouth, New Hampshire
One New Hampshire Avenue is Portsmouth's premier Class A office building. This building features a secured lower-level parking garage, deli,...
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1
N/A
1,500 - 7,500 SF
107,746 SF
Office
Office Building
Office for Lease - 100 International Dr
Office for Lease - 100 International Dr
Portsmouth, New Hampshire
100 International Dr. is a Class A office building located at Pease International Tradeport. An on-site Cafe located on the first floor, private...
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1
N/A
1,178 SF
113,011 SF
Office
Office Building
Office for Lease - 2 International Dr
Office for Lease - 2 International Dr
Portsmouth, New Hampshire
2 International Dr is Pease International Tradeport's signature office building. Located on the most prominent corner of the Tradeport, 2...
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1
N/A
7,000 SF
88,467 SF
Office
Office Building
Office for Lease - Harbour Place
Office for Lease - Harbour Place
Portsmouth, New Hampshire
Harbour Place is one of the most exclusive office buildings in Portsmouth offering sweeping views of the Piscataqua River, Strawberry...
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1
N/A
2,573 SF
100,112 SF
Office
Office Building
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