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Below are 226 Florence commercial real estate listings out of over nearly 800,000 total properties available on LoopNet.com.

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705 S. Irby Street
705 S. Irby Street
Florence, South Carolina
Centrally located in downtown Florence within the "redevelopment district", this building was constructed in 1991. It features large open spaces...
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$279,900
5,625 SF
N/A
Office
Office Building
315 W. Pine Street
315 W. Pine Street
Florence, South Carolina
Centrally located in downtown Florence within the "redevelopment district", this brick 2 story office building was constructed in 2006. The 1st...
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$2,000,000
10,534 SF
N/A
Office
Office Building
Former Elliott Gin Lumber
Former Elliott Gin Lumber
Florence, South Carolina
This is an excellent opportunity to be located on one of Florence' s heaviest traveled commercial and commuter corridors, US Highway 52, with...
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$613,000
46,230 SF
N/A
Retail
Free Standing Bldg
Florence Mall
Florence Mall
Florence, South Carolina
Florence Mall is a prominent shopping center in Florence, SC located at "Five Points," the intersection of West Palmetto Street, State Road S...
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8
N/A
1,500 - 13,914 SF
357,312 SF
Retail
Regional Center/Mall
714 S. Coit St.
714 S. Coit St.
Florence, South Carolina
This +/- 2,959 square foot free-standing, renovated office building has attractive street presence and an inviting entrance with a covered walk...
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1
$12.00
2,959 SF
2,959 SF
Office
Office Building
Ruby Tuesday
Ruby Tuesday
Florence, South Carolina
Marcus & Millichap is pleased to present the exclusive listing for a single-tenant, freestanding Ruby Tuesday located in Florence, South Carolina...
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$2,400,000
4,930 SF
5.26%
Retail
Restaurant
Walgreens
Walgreens
Florence, South Carolina
The subject property is located at the northeast corner of South Irby Street and Cherokee Road in the heart of downtown Florence. The property...
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$7,845,000
14,820 SF
4.85%
Retail
Free Standing Bldg
N. Cashua Drive-44 Acres
N. Cashua Drive-44 Acres
Florence, South Carolina
This clear/level parcel has older home, silo, and tractor shed that conveys with property.
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$910,000
44.38 Acres
Land
Commercial/Other (land)
Former King Drug Co.
Former King Drug Co.
Florence, South Carolina
This is an excellent opportunity to be located on one of Florence' s heaviest traveled commercial and commuter corridors, US Highway 52, with...
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$439,000
24,000 SF
N/A
Office
Office Building
805 N. Cashua Dr.
805 N. Cashua Dr.
Florence, South Carolina
This location offers excellent visibility and an ideal identity site. Located on North Cashua Drive, this free standing building is neighbored by...
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$11.25
2,400 SF
2,400 SF
Office
Office Building
Second Loop Rd.
Second Loop Rd.
Florence, South Carolina
This highly visible commercial development site is situated on Second Loop Road, Florence' s premier business thoroughfare between South and West...
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$0.57
0.96 AC
0.00 Acres
Land
Commercial/Other (land)
Tara Village Lots 26 $6000 each
Tara Village Lots 26 $6000 each
Florence, South Carolina
Beautiful lot to build your dream home! All information is to be verified by buyerThere are 25 lots total (19 on Macree) (6 on Gable). $6,000 per...
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$6,000
0.20 Acres
Land
Residential (land)
2240 Douglas St.
2240 Douglas St.
Florence, South Carolina
This office building is located near an established business district with excellent visibility from I-95. The building is the first in a 50 acre...
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1
$11.05
2,389 SF
N/A
Office
Office Building
Palmetto Plaza
Palmetto Plaza
Florence, South Carolina
1651 W. Palmetto St +/- 2,000 SF retail suite, former Jones Smith Jewelers, with large showroom area, storage/work area, +/- 384 SF warehouse,...
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2
$.90 - $10.80
2,000 SF
10,000 SF
Office
Office Building
1301 S. Irby Street
1301 S. Irby Street
Florence, South Carolina
Prime commercial site. Lot is approximately 1 acre with additional land potentially available. Zoned B-3 (General Use). Traffic signal in front...
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$427,703
1.00 Acres
Land
Commercial/Other (land)
N. Cashua Dr. and Sally Hill Farms Blvd.
N. Cashua Dr. and Sally Hill Farms Blvd.
Florence, South Carolina
This is an excellent opportunity to be located off one of Florence' s heaviest traveled commercial and commuter corridors, approximately one mile...
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$120,000 - $325,000
1.81 - 4.03 Acres
Land
Commercial/Other (land)
N. Williston Road
N. Williston Road
Florence, South Carolina
Prime commercial location on Hwy 327 and only 2 miles from I-95. Includes road frontage on Byrnes Blvd. with water and sewer nearby. Size is an...
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$350,000
10.00 Acres
Land
Commercial/Other (land)
Former Doc's Firearms
Former Doc's Firearms
Florence, South Carolina
The former location of Doc' s Firearms is located in the out parcel of one of Florence' s most established and well kept shopping centers. The...
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1
$9.60
1,500 SF
1,500 SF
Office
Office Building
Former Florence Little Theater
Former Florence Little Theater
Florence, South Carolina
+/- 12,000 Square Feet 4.76 Acres Available Excellent Demographics +/- 755 Ft. Fronting S. Cashua Drive Municipal Water & Sere to the...
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$350,000
4.76 Acres
Land
Office (land)
Applebee's Neighborhood Grill & Bar
Applebee's Neighborhood Grill & Bar
Florence, South Carolina
The subject property is a ±3,552 square foot freestanding Applebee's Neighborhood Grill & Bar restaurant located at 811 South Irby Street in...
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$2,176,000
3,552 SF
8.00%
Retail
Restaurant
Pamplico Highway
Pamplico Highway
Florence, South Carolina
1.35 Acres on busy highway. Option to lease or purchase.
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$330,000
1.35 Acres
Land
Commercial/Other (land)
804 Second Loop Rd
804 Second Loop Rd
Florence, South Carolina
3 units available: one former physician's office, one former scrapbook store and one former children's clothing store.
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3
$10.50 - $12.60
1,471 - 2,440 SF
6,200 SF
Retail
Strip Center
Executive Park
Executive Park
Florence, South Carolina
Two story office building. Two suites upstairs and one suite downstairs. Rent includes all expenses and utilities.
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3
$14.20 - $15.98
711 - 2,676 SF
8,898 SF
Office
Office Building
Former Sav-Way
Former Sav-Way
Florence, South Carolina
3736 Square Foot Masonry Facility Built in 1988 Lot Size: Approximately 1.447 Acres 5-15,000 Gallon Steel Tanks w/ ...
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$619,000
3,736 SF
N/A
Retail
Service/Gas Station
Retail Property
Florence, South Carolina
Strong investment opportunity near downtown redevelopment area. Six unit strip center in busy, high traffic area. High occupancy. Billboard...
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$599,000
17,637 SF
N/A
Retail
Strip Center

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LoopNet's Florence commercial real estate listings include farms, multifamily apartments, office buildings, retail space, vacant land, hotels and motels, gas stations, warehouses, restaurants for lease and much more.

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