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Below are 235 Florence commercial real estate listings out of over nearly 800,000 total properties available on LoopNet.com.

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235 Listings

614 W. Palmetto Street
614 W. Palmetto Street
Florence, South Carolina
Corner of Palmetto and Park Avenue. Dental office with two suites of 2906 SF and 1299 SF. Great location and building for medical or office use or...
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$336,000
4,205 SF
N/A
Office
Medical Office
Academy Sports + Outdoors & Party City
Academy Sports + Outdoors & Party City
Florence, South Carolina
The subject property is a brand new 2014 construction 70,552-square foot building featuring Academy Sports + Outdoors and Party City in Florence,...
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$10,813,569
70,552 SF
6.50%
Retail
Retail (Other)
Palmetto Plaza
Palmetto Plaza
Florence, South Carolina
1651 W. Palmetto St +/- 2,000 SF retail suite, former Jones Smith Jewelers, with large showroom area, storage/work area, +/- 384 SF warehouse,...
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2
$10.80
2,000 SF
10,000 SF
Office
Office Building
Former Dry Cleaners
Former Dry Cleaners
Florence, South Carolina
The subject property fronts directly onto the W. Palmetto commercial corridor. The area provides a variety of businesses including retail,...
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$8.54
2,600 SF
2,600 SF
Office
Office Building
NNN Walgreens | 19 Years | Near Medical Center
NNN Walgreens | 19 Years | Near Medical Center
Florence, South Carolina
Walgreens is located at the northeast corner of South Irby Street and Cherokee Road in the heart of Florence, SC. The property benefits from...
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$7,609,020
14,820 SF
5.00%
Retail
Retail Pad
Former Car Lot
Former Car Lot
Florence, South Carolina
Available is an excellent commercial office/ retail building located on Plamplico Hwy. This site is located in a neighborhood with an array of...
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$292,000
1,260 SF
N/A
Office
Office Building
Bank Owned Property
Bank Owned Property
Florence, South Carolina
Property consists of 80+/- acres just off of I-95 & Highway 52 (West Lucas Street). The property is an irregular shaped tract with frontage on...
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Not Disclosed
80.00 Acres
Land
Residential (land)
1931 Second Loop Road
1931 Second Loop Road
Florence, South Carolina
Excellent retail/restaurant location next to First Citizens Bank. Formerly used as restaurant/nightclub but originally built for retail. High...
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$395,000
4,249 SF
N/A
Retail
Free Standing Bldg
705 S. Irby Street
705 S. Irby Street
Florence, South Carolina
Centrally located in downtown Florence within the "redevelopment district", this building was constructed in 1991. It features large open spaces...
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$279,900
5,625 SF
N/A
Office
Office Building
315 W. Pine Street
315 W. Pine Street
Florence, South Carolina
Centrally located in downtown Florence within the "redevelopment district", this brick 2 story office building was constructed in 2006. The 1st...
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$2,000,000
10,534 SF
N/A
Office
Office Building
Former Elliott Gin Lumber
Former Elliott Gin Lumber
Florence, South Carolina
This is an excellent opportunity to be located on one of Florence' s heaviest traveled commercial and commuter corridors, US Highway 52, with...
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$613,000
46,230 SF
N/A
Retail
Free Standing Bldg
Florence Mall
Florence Mall
Florence, South Carolina
Florence Mall is a prominent shopping center in Florence, SC located at "Five Points," the intersection of West Palmetto Street, State Road S...
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3
N/A
1,500 - 3,346 SF
357,312 SF
Retail
Regional Center/Mall
714 S. Coit St.
714 S. Coit St.
Florence, South Carolina
This +/- 2,959 square foot free-standing, renovated office building has attractive street presence and an inviting entrance with a covered walk...
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$12.00
2,959 SF
2,959 SF
Office
Office Building
Land
Florence, South Carolina
This piece of land is approximately 16 + or minus acres. Owner let me know it is unzoned and it could be zoned commercial or residential...
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$1,600,000
16.00 Acres
Land
Commercial/Other (land)
Land
Florence, South Carolina
Great piece of property which is approximately 56 acres plus or minus. This property is in Florence County. Property is unzoned and owner believes...
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$1,800,000
56.00 Acres
Land
Commercial/Other (land)
Land
Florence, South Carolina
According to the owner the property is unzoned and could possibly be commercial or residential. The property includes approximately 9 plus or...
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$1,250,000
9.00 Acres
Land
Commercial/Other (land)
N. Cashua Drive-44 Acres
N. Cashua Drive-44 Acres
Florence, South Carolina
This clear/level parcel has older home, silo, and tractor shed that conveys with property.
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$910,000
44.38 Acres
Land
Commercial/Other (land)
Former King Drug Co.
Former King Drug Co.
Florence, South Carolina
This is an excellent opportunity to be located on one of Florence' s heaviest traveled commercial and commuter corridors, US Highway 52, with...
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$439,000
24,000 SF
N/A
Office
Office Building
805 N. Cashua Dr.
805 N. Cashua Dr.
Florence, South Carolina
This location offers excellent visibility and an ideal identity site. Located on North Cashua Drive, this free standing building is neighbored by...
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$11.25
2,400 SF
2,400 SF
Office
Office Building
Second Loop Rd.
Second Loop Rd.
Florence, South Carolina
This highly visible commercial development site is situated on Second Loop Road, Florence' s premier business thoroughfare between South and West...
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$0.57
0.96 AC
0.00 Acres
Land
Commercial/Other (land)
Tara Village Lots 26 $6000 each
Tara Village Lots 26 $6000 each
Florence, South Carolina
Beautiful lot to build your dream home! All information is to be verified by buyerThere are 25 lots total (19 on Macree) (6 on Gable). $6,000 per...
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$6,000
0.20 Acres
Land
Residential (land)
2240 Douglas St.
2240 Douglas St.
Florence, South Carolina
This office building is located near an established business district with excellent visibility from I-95. The building is the first in a 50 acre...
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$8.50
2,389 SF
NaN SF
Office
Office Building
1301 S. Irby Street
1301 S. Irby Street
Florence, South Carolina
Prime commercial site. Lot is approximately 1 acre with additional land potentially available. Zoned B-3 (General Use). Traffic signal in front...
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$427,703
1.00 Acres
Land
Commercial/Other (land)
N. Cashua Dr. and Sally Hill Farms Blvd.
N. Cashua Dr. and Sally Hill Farms Blvd.
Florence, South Carolina
This is an excellent opportunity to be located off one of Florence' s heaviest traveled commercial and commuter corridors, approximately one mile...
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$120,000 - $325,000
1.81 - 4.03 Acres
Land
Commercial/Other (land)
N. Williston Road
N. Williston Road
Florence, South Carolina
Prime commercial location on Hwy 327 and only 2 miles from I-95. Includes road frontage on Byrnes Blvd. with water and sewer nearby. Size is an...
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$210,000
10.00 Acres
Land
Commercial/Other (land)

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LoopNet's Florence commercial real estate listings include farms, multifamily apartments, office buildings, retail space, vacant land, hotels and motels, gas stations, warehouses, restaurants for lease and much more.

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