10055 Barnes Canyon Rd
San Diego, CA 92121
Building E · Office Property for Lease · 37,712 SF

Positioned on the top floor of one of San Diego’s premier life science buildings, the sublease at 10055 Barnes Canyon Rd offers a rare blend of lab and office space in the heart of the Alexandria Tech Center. This fully furnished, plug-and-play suite features a 50/50 lab-to-office ratio, ideal for biotech, pharmaceutical, or R&D users seeking immediate occupancy and operational efficiency. The building’s basement houses a commercial vivarium operated by Charles River Labs, providing direct access to specialized research infrastructure. Tenants benefit from the extensive amenities of Alexandria Tech Center, including indoor/outdoor fitness facilities with trainers and classes, sport courts, conferencing areas, restaurants, bars, lounges, and covered parking—all designed to support productivity and employee wellness. With flexible floor division options ranging from 12,500 to 37,712 SF, and availability within 30 days, this sublease presents a strategic opportunity for companies looking to scale quickly in a highly sought-after innovation corridor. The NNN lease rate is competitively positioned at $4.95/SF, with expenses estimated at $2.65/SF.