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105 Broadway
Cambridge, MA 02142
Office Property for Lease · 47,400 SF

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SUBLEASE HIGHLIGHTS

  • Situated in the epicenter of Cambridge’s innovation district, surrounded by top-tier research institutions and biotech firms
  • Currently offering 46,594 RSF across two full floors (2nd and 4th), ideal for lab or office use
  • Designed to support life science operations with flexible floor plates and infrastructure suitable for lab conversion
  • Home to major tenants including MIT, Thermo Fisher, and the Broad Institute, reflecting the building’s prestige and functionality
  • Boston Properties is exploring plans to redevelop the site into a modern lab-and-office tower, signaling long-term value and adaptability
  • Excellent connectivity via MBTA Red Line and major roadways, enhancing commuter convenience and regional access.

PROPERTY OVERVIEW

Located in the heart of Kendall Square, 105 Broadway is a premier Class A life science and office building spanning approximately 152,664 square feet across seven stories. Built in 1990, the property has long served as a cornerstone for innovation, housing prominent tenants such as Thermo Fisher Scientific, the Massachusetts Institute of Technology, and the Broad Institute 1. The building offers 46,594 RSF of sublease space, with 23,700 square feet available on both the 2nd and 4th floors 2. Its strategic location places it within one of the most dynamic biotech and research ecosystems in the world, offering unmatched access to talent, transit, and institutional partnerships. The property is currently managed by Boston Properties (BXP), which has proposed redevelopment plans to transform the site into a next-generation lab-and-office tower.

  • Bio-Tech/ Lab Space
  • Bus Line
  • Metro/Subway
  • Property Manager on Site
  • Restaurant
  • Security System
  • Energy Star Labeled
  • Air Conditioning

PROPERTY FACTS

Building Type
Office
Year Built/Renovated
1990/2000
LoopNet Rating
4 Star
Building Height
7 Stories
Building Size
153,646 SF
Building Class
A
Typical Floor Size
21,809 SF
Unfinished Ceiling Height
12’
Parking
1,100 Covered Parking Spaces
  • Listing ID: 37107091

  • Date on Market: 8/4/2025

  • Last Updated:

  • Address: 105 Broadway, Cambridge, MA 02142

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