1105 State St 5,760 SF of Office/Medical Space Available in Cayce, SC 29033

Positioned in the heart of Cayce’s central hub, 1105 State Street offers a compelling opportunity for tenants seeking a professional or medical office environment with excellent visibility and immediate access to Columbia’s most active corridors. The property sits just off the intersection of State Street and Knox Abbott Drive, an area known for steady vehicular activity, walkability, and convenient connections to neighboring districts including West Columbia, the Congaree Riverfront, and the University of South Carolina. Its placement within minutes of downtown Columbia, the Vista, and Interstate 77 creates an accessible location for both clients and employees traveling from across the region. The building features a single-story layout suited for a variety of office uses and offers ADA accessibility for seamless customer access. A large fenced parking area, paired with a rear loading door, enhances functionality for medical providers, professional service firms, or organizations needing secure operational space. Tenants benefit from the property’s proximity to Guignard Park, established residential neighborhoods, and a strong mix of retail and dining options along State Street and Knox Abbott Drive. The surrounding area continues to attract both local patrons and visitors drawn to the nearby Three Rivers Greenway, Parkland Plaza, and Riverwalk Park, strengthening daytime and evening activity. With a competitive lease structure at a net rate of $20.00 per square foot plus utilities and janitorial services, the building presents a cost-effective solution in a high-demand corridor. Its combination of practical office attributes, strong neighborhood amenities, and strategic connectivity makes 1105 State Street a standout option for organizations seeking convenience, visibility, and a well-balanced environment within the Cayce and Columbia markets.