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Walker Medical Building 12855 N 40 Dr 463 - 19,861 SF of Office/Medical Space Available in Saint Louis, MO 63141

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HIGHLIGHTS

  • 12855 N Forty Drive, the Walker Medical Building, is a Class A MOB with a multi-specialty tenant mix in West St. Louis.
  • Affluent, health-conscious locale with an average annual household income of over $162,000 reported within a 3-mile radius.
  • Minutes to three of the area’s major hospitals with direct access to Highway 40/Interstate 64, leading to Interstate 270 and MO-141.
  • ADA-accessible property featuring a two-level parking garage, 24-hour card access, and a backup generator.
  • Equipped for lab testing, dental practices, advanced imaging, physical therapy, surgery, concierge medicine, primary care, and much more.

ALL AVAILABLE SPACES(5)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 150
  • 7,074 SF
  • Negotiable
  • $36.00 /SF/YR $3.00 /SF/MO $254,664 /YR $21,222 /MO
  • Office/Medical
  • -
  • June 01, 2026

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Fits 18 - 57 People
  • 1st Floor, Ste 180A
  • 463 SF
  • Negotiable
  • $30.00 /SF/YR $2.50 /SF/MO $13,890 /YR $1,158 /MO
  • Office/Medical
  • Full Build-Out
  • Now

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Fits 2 - 4 People
  • Reception Area
  • Wheelchair Accessible
  • Office intensive layout
  • Laboratory
  • Central Air Conditioning
  • 2nd Floor, Ste 200
  • 2,500-5,986 SF
  • Negotiable
  • $30.00 /SF/YR $2.50 /SF/MO $179,580 /YR $14,965 /MO
  • Office/Medical
  • Full Build-Out
  • 30 Days

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Fits 7 - 48 People
  • Reception Area
  • Wheelchair Accessible
  • Office intensive layout
  • Laboratory
  • Central Air Conditioning
  • 2nd Floor, Ste 260
  • 3,088 SF
  • Negotiable
  • $30.00 /SF/YR $2.50 /SF/MO $92,640 /YR $7,720 /MO
  • Office/Medical
  • Full Build-Out
  • Now

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Fits 8 - 25 People
  • Laboratory
  • Central Air Conditioning
  • Office intensive layout
  • Can be combined with additional space(s) for up to 6,338 SF of adjacent space
  • Reception Area
  • Wheelchair Accessible
  • 2nd Floor, Ste 275
  • 3,250 SF
  • Negotiable
  • $30.00 /SF/YR $2.50 /SF/MO $97,500 /YR $8,125 /MO
  • Office/Medical
  • -
  • February 01, 2026
  • Rate includes utilities, building services and property expenses
  • Can be combined with additional space(s) for up to 6,338 SF of adjacent space
  • Fits 5 - 25 People
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 150 7,074 SF Negotiable $36.00 /SF/YR $3.00 /SF/MO $254,664 /YR $21,222 /MO Office/Medical - June 01, 2026
1st Floor, Ste 180A 463 SF Negotiable $30.00 /SF/YR $2.50 /SF/MO $13,890 /YR $1,158 /MO Office/Medical Full Build-Out Now
2nd Floor, Ste 200 2,500-5,986 SF Negotiable $30.00 /SF/YR $2.50 /SF/MO $179,580 /YR $14,965 /MO Office/Medical Full Build-Out 30 Days
2nd Floor, Ste 260 3,088 SF Negotiable $30.00 /SF/YR $2.50 /SF/MO $92,640 /YR $7,720 /MO Office/Medical Full Build-Out Now
2nd Floor, Ste 275 3,250 SF Negotiable $30.00 /SF/YR $2.50 /SF/MO $97,500 /YR $8,125 /MO Office/Medical - February 01, 2026

1st Floor, Ste 150

Size
7,074 SF
Term
Negotiable
Rental Rate
$36.00 /SF/YR $3.00 /SF/MO $254,664 /YR $21,222 /MO
Space Use
Office/Medical
Condition
-
Available
June 01, 2026

1st Floor, Ste 180A

Size
463 SF
Term
Negotiable
Rental Rate
$30.00 /SF/YR $2.50 /SF/MO $13,890 /YR $1,158 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 200

Size
2,500-5,986 SF
Term
Negotiable
Rental Rate
$30.00 /SF/YR $2.50 /SF/MO $179,580 /YR $14,965 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
30 Days

2nd Floor, Ste 260

Size
3,088 SF
Term
Negotiable
Rental Rate
$30.00 /SF/YR $2.50 /SF/MO $92,640 /YR $7,720 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 275

Size
3,250 SF
Term
Negotiable
Rental Rate
$30.00 /SF/YR $2.50 /SF/MO $97,500 /YR $8,125 /MO
Space Use
Office/Medical
Condition
-
Available
February 01, 2026

1st Floor, Ste 150

Size 7,074 SF
Term Negotiable
Rental Rate $36.00 /SF/YR
Space Use Office/Medical
Condition -
Available June 01, 2026

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Fits 18 - 57 People

1st Floor, Ste 180A

Size 463 SF
Term Negotiable
Rental Rate $30.00 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Office intensive layout
  • Fits 2 - 4 People
  • Laboratory
  • Reception Area
  • Central Air Conditioning
  • Wheelchair Accessible

2nd Floor, Ste 200

Size 2,500-5,986 SF
Term Negotiable
Rental Rate $30.00 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available 30 Days

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Office intensive layout
  • Fits 7 - 48 People
  • Laboratory
  • Reception Area
  • Central Air Conditioning
  • Wheelchair Accessible

2nd Floor, Ste 260

Size 3,088 SF
Term Negotiable
Rental Rate $30.00 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Contact broker for more information.

  • Rate includes utilities, building services and property expenses
  • Office intensive layout
  • Fits 8 - 25 People
  • Can be combined with additional space(s) for up to 6,338 SF of adjacent space
  • Laboratory
  • Reception Area
  • Central Air Conditioning
  • Wheelchair Accessible

2nd Floor, Ste 275

Size 3,250 SF
Term Negotiable
Rental Rate $30.00 /SF/YR
Space Use Office/Medical
Condition -
Available February 01, 2026

  • Rate includes utilities, building services and property expenses
  • Fits 5 - 25 People
  • Can be combined with additional space(s) for up to 6,338 SF of adjacent space

PROPERTY OVERVIEW

Join the ranks of leading healthcare specialists and take advantage of superior visibility and connectivity with one of the high-end suites offered at 12855 N Forty Drive, the Walker Medical Building. 12855 N Forty Drive spans approximately 150,000 square feet across four stories and features a two-story parking garage, 24-hour access, ADA accessibility, and a backup generator for seamless operations and access. New tenants will be in good company with co-occupants in pediatrics, gastroenterology, neurosurgery, cardiology, family medicine, podiatry, general surgery, psychiatry, and more, a diverse mix to broaden referral networks. Walker Medical Building benefits from proximity to three major hospitals, Mercy (formerly St. John’s), Missouri Baptist, and St. Luke's, all of which are less than 10 minutes from the property. Local residents report a high payor mix and prioritize health and wellness with some of the most prestigious communities nearby, such as Town and Country, Chesterfield, Clarkson Valley, Ladue, and Des Peres. Connections to these patient pools are streamlined via direct access to Interstate 64 and other close arterial roadways. Many residents are organically drawn here, making this a convenient destination, with several local schools, colleges, country clubs, parks, and shopping districts moments away.

  • 24 Hour Access
  • Bio-Tech/ Lab Space
  • Wheelchair Accessible
  • Backup Power / Generators

PROPERTY FACTS

Building Type
Office
Year Built/Renovated
1983/2006
Building Height
4 Stories
Building Size
151,844 SF
Building Class
A
Typical Floor Size
37,961 SF
Unfinished Ceiling Height
8’
Parking
434 Surface Parking Spaces
437 Covered Parking Spaces

SELECT TENANTS

  • FLOOR
  • TENANT NAME
  • INDUSTRY
  • LL
  • Arch Cancer Care
  • Health Care and Social Assistance
  • 1st
  • Gateway Endoscopy Center
  • Health Care and Social Assistance
  • 2nd
  • Mercy Clinic Internal Medicine - Creve Coeur
  • Health Care and Social Assistance
  • 1st
  • Neurosurgery of St. Louis
  • Health Care and Social Assistance
  • 3rd
  • Urology of St. Louis
  • Health Care and Social Assistance
  • Listing ID: 4077470

  • Date on Market: 1/12/2026

  • Last Updated:

  • Address: 12855 N 40 Dr, Saint Louis, MO 63141

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