131 Commonwealth Dr
Greenville, SC 29615
St. Francis Medical Plaza 1 (Greenville) · Property For Lease

St. Francis Medical Plaza I at 131 Commonwealth Dr is a medical office building located on the campus of Bon Secours St. Francis Eastside Hospital in Greenville, South Carolina. Positioned within a well-established healthcare hub, the property benefits from direct hospital adjacency and a strong outpatient ecosystem that supports long-term practice stability and consistent patient demand. The Eastside campus is widely recognized for diverse care capabilities, including 24/7 emergency services, joint replacement care, and comprehensive labor, delivery, and neonatal support. Medical Plaza I is attached to the hospital, offering immediate proximity to key clinical services that enhance patient convenience and provider collaboration. This campus positioning supports coordinated care pathways and creates an efficient destination for appointment-driven outpatient visits. A mix of healthcare specialists further strengthens the on-site environment, helping consolidate services and build a trusted medical address for the surrounding community. Accessibility is a defining advantage of the property. The building is situated adjacent to Interstate 385 with convenient connections between Interstate 85 and US-276, enabling efficient regional access for patients, physicians, and staff traveling from across the Upstate. This connectivity supports both daily commuting and broader patient draw beyond the immediate neighborhood. The campus experience is further supported by free parking with a strong combination of surface and covered options, helping streamline arrival and circulation throughout the day. On-site property management, maintenance, and security provide dependable building support and reinforce a tenant-focused operating environment. Adding to its convenience, the property is within a short drive of Greenville’s premier retail corridor, including Haywood Mall, the Shops at Greenridge, and the Woodruff Shopping Center. With its hospital attachment, regional accessibility, parking convenience, and well-supported operations, St. Francis Medical Plaza I offers an exceptional place of care for providers seeking a proven outpatient destination in the Greenville market.