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Building A 1350 Cleveland St 1,776 - 8,201 SF of Office Space Available in Greenville, SC 29607

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Highlights

  • Prime medical office location near Greenville’s healthcare hub
  • Prominent Cleveland Street signage for maximum visibility
  • Convenient access to I-85, I-385, and downtown Greenville
  • Two-suite configuration with direct parking access on both levels
  • Zoned RNX-B, supporting diverse medical and professional uses

All Available Spaces(2)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • Ground, Ste B
  • 1,776 SF
  • Negotiable
  • $16.00 /SF/YR $1.33 /SF/MO $28,416 /YR $2,368 /MO
  • Office
  • Full Build-Out
  • Now

Positioned in the heart of Greenville’s vibrant medical corridor, 1350 A Cleveland Street offers a prime opportunity for healthcare providers seeking a well-connected and highly visible location. This ±8,201 SF medical office building is thoughtfully designed to accommodate modern medical practices with two distinct suites: Suite A on the main floor and Suite B on the lower level. Both spaces provide direct access from parking areas, ensuring convenience for patients and staff alike. The property boasts exceptional signage along Cleveland Street, enhancing visibility and brand presence in a high-traffic area. Zoned RNX-B, the building supports a range of medical and professional uses, making it a versatile choice for growing practices. Its strategic location places tenants within minutes of Greenville’s major hospitals, specialty clinics, and thriving residential neighborhoods, creating a strong referral network and patient base. With a competitive lease rate of $16.00/SF NNN, this property combines affordability with functionality. Tenants will benefit from proximity to downtown Greenville, easy access to I-85 and I-385, and a surrounding community known for its robust demographics and economic growth. This is an ideal setting for practices looking to elevate their presence in one of South Carolina’s most dynamic healthcare markets.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Built-Out as Standard Office
  • Fits 5 - 15 People
  • Lower level, ±1,776 SF, separate entrance
  • 1st Floor, Ste A
  • 6,425 SF
  • Negotiable
  • $16.00 /SF/YR $1.33 /SF/MO $102,800 /YR $8,567 /MO
  • Office
  • Full Build-Out
  • Now

Positioned in the heart of Greenville’s vibrant medical corridor, 1350 A Cleveland Street offers a prime opportunity for healthcare providers seeking a well-connected and highly visible location. This ±8,201 SF medical office building is thoughtfully designed to accommodate modern medical practices with two distinct suites: Suite A on the main floor and Suite B on the lower level. Both spaces provide direct access from parking areas, ensuring convenience for patients and staff alike. The property boasts exceptional signage along Cleveland Street, enhancing visibility and brand presence in a high-traffic area. Zoned RNX-B, the building supports a range of medical and professional uses, making it a versatile choice for growing practices. Its strategic location places tenants within minutes of Greenville’s major hospitals, specialty clinics, and thriving residential neighborhoods, creating a strong referral network and patient base. With a competitive lease rate of $16.00/SF NNN, this property combines affordability with functionality. Tenants will benefit from proximity to downtown Greenville, easy access to I-85 and I-385, and a surrounding community known for its robust demographics and economic growth. This is an ideal setting for practices looking to elevate their presence in one of South Carolina’s most dynamic healthcare markets.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Fully Built-Out as Standard Office
  • Fits 17 - 52 People
  • ±6,425 SF, direct parking access
Space Size Term Rental Rate Space Use Condition Available
Ground, Ste B 1,776 SF Negotiable $16.00 /SF/YR $1.33 /SF/MO $28,416 /YR $2,368 /MO Office Full Build-Out Now
1st Floor, Ste A 6,425 SF Negotiable $16.00 /SF/YR $1.33 /SF/MO $102,800 /YR $8,567 /MO Office Full Build-Out Now

Ground, Ste B

Size
1,776 SF
Term
Negotiable
Rental Rate
$16.00 /SF/YR $1.33 /SF/MO $28,416 /YR $2,368 /MO
Space Use
Office
Condition
Full Build-Out
Available
Now

1st Floor, Ste A

Size
6,425 SF
Term
Negotiable
Rental Rate
$16.00 /SF/YR $1.33 /SF/MO $102,800 /YR $8,567 /MO
Space Use
Office
Condition
Full Build-Out
Available
Now

Ground, Ste B

Size 1,776 SF
Term Negotiable
Rental Rate $16.00 /SF/YR
Space Use Office
Condition Full Build-Out
Available Now

Positioned in the heart of Greenville’s vibrant medical corridor, 1350 A Cleveland Street offers a prime opportunity for healthcare providers seeking a well-connected and highly visible location. This ±8,201 SF medical office building is thoughtfully designed to accommodate modern medical practices with two distinct suites: Suite A on the main floor and Suite B on the lower level. Both spaces provide direct access from parking areas, ensuring convenience for patients and staff alike. The property boasts exceptional signage along Cleveland Street, enhancing visibility and brand presence in a high-traffic area. Zoned RNX-B, the building supports a range of medical and professional uses, making it a versatile choice for growing practices. Its strategic location places tenants within minutes of Greenville’s major hospitals, specialty clinics, and thriving residential neighborhoods, creating a strong referral network and patient base. With a competitive lease rate of $16.00/SF NNN, this property combines affordability with functionality. Tenants will benefit from proximity to downtown Greenville, easy access to I-85 and I-385, and a surrounding community known for its robust demographics and economic growth. This is an ideal setting for practices looking to elevate their presence in one of South Carolina’s most dynamic healthcare markets.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 5 - 15 People
  • Space is in Excellent Condition
  • Lower level, ±1,776 SF, separate entrance

1st Floor, Ste A

Size 6,425 SF
Term Negotiable
Rental Rate $16.00 /SF/YR
Space Use Office
Condition Full Build-Out
Available Now

Positioned in the heart of Greenville’s vibrant medical corridor, 1350 A Cleveland Street offers a prime opportunity for healthcare providers seeking a well-connected and highly visible location. This ±8,201 SF medical office building is thoughtfully designed to accommodate modern medical practices with two distinct suites: Suite A on the main floor and Suite B on the lower level. Both spaces provide direct access from parking areas, ensuring convenience for patients and staff alike. The property boasts exceptional signage along Cleveland Street, enhancing visibility and brand presence in a high-traffic area. Zoned RNX-B, the building supports a range of medical and professional uses, making it a versatile choice for growing practices. Its strategic location places tenants within minutes of Greenville’s major hospitals, specialty clinics, and thriving residential neighborhoods, creating a strong referral network and patient base. With a competitive lease rate of $16.00/SF NNN, this property combines affordability with functionality. Tenants will benefit from proximity to downtown Greenville, easy access to I-85 and I-385, and a surrounding community known for its robust demographics and economic growth. This is an ideal setting for practices looking to elevate their presence in one of South Carolina’s most dynamic healthcare markets.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 17 - 52 People
  • Space is in Excellent Condition
  • ±6,425 SF, direct parking access

Property Overview

This well-positioned medical office building offers a professional environment tailored for healthcare providers and specialty practices. Featuring a modern two-level design, the property includes a spacious main floor and a lower-level suite, each with direct access from dedicated parking areas for maximum convenience. The building’s layout supports efficient patient flow and operational flexibility, making it ideal for multi-practice configurations or a single tenant seeking ample space. Prominent signage along Cleveland Street ensures strong visibility in a high-traffic corridor, while the RNX-B zoning accommodates a variety of medical and professional uses. The property’s location in Greenville places it within minutes of major hospitals, specialty clinics, and thriving residential neighborhoods, creating a strong referral network and patient base. Easy access to I-85 and I-385 enhances connectivity for staff and patients traveling from across the region. With its strategic location, functional design, and competitive lease terms, this building represents an exceptional opportunity for medical professionals looking to establish or expand their presence in one of South Carolina’s most dynamic healthcare markets.

  • Signage

Property Facts

Building Type
Office
Year Built
2023
Building Height
1 Story
Building Size
8,201 SF
Building Class
C
Typical Floor Size
8,201 SF
Unfinished Ceiling Height
14’
Parking
32 Surface Parking Spaces
18 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • Greenville Health System
  • Educational Services
  • Listing ID: 37743249

  • Date on Market: 9/19/2025

  • Last Updated:

  • Address: 1350 Cleveland St, Greenville, SC 29607

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