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2110 Southern Expressway 20.95 Acres of Commercial Land in Cape Girardeau, MO 63703

Investment Highlights
- All necessary utilities available: water, electric, and sewer service to site.
- Quick access to Highway 74 and Interstate 55 supporting regional traffic flows.
- Positioned in a thriving commercial corridor with prominence and visibility in the market.
- Direct access to Kingshighway and Southern Expressway for superior connectivity.
- Graded property offering ease of site preparation; divisible to accommodate multiple users.
Executive Summary
An exceptional redevelopment tract of ±18.40 acres is available along Southern Expressway in Cape Girardeau, Missouri. This prime site offers seamless connectivity to Highway 74 and Interstate 55, making it ideal for large-scale commercial developments or industrial campuses requiring strategic regional access.
Graded and development-ready, the property features direct frontage along Kingshighway — Cape Girardeau’s primary business corridor — providing unmatched visibility and exposure to high traffic volumes. All major utilities, including water, electric, and sewer service, are available on-site, simplifying planning and accelerating construction timelines.
With the ability to subdivide, this acreage offers flexibility for multiple pads or end-user requirements. Positioned within the city's growth loop and adjoining major road networks, 2110 Southern Expressway stands as a compelling opportunity for retailers, industrial operators, or mixed-use developers targeting expansion in Southeast Missouri's hub.
Graded and development-ready, the property features direct frontage along Kingshighway — Cape Girardeau’s primary business corridor — providing unmatched visibility and exposure to high traffic volumes. All major utilities, including water, electric, and sewer service, are available on-site, simplifying planning and accelerating construction timelines.
With the ability to subdivide, this acreage offers flexibility for multiple pads or end-user requirements. Positioned within the city's growth loop and adjoining major road networks, 2110 Southern Expressway stands as a compelling opportunity for retailers, industrial operators, or mixed-use developers targeting expansion in Southeast Missouri's hub.
Property Facts
| Sale Type | Investment | Property Subtype | Commercial |
| No. Lots | 1 | Total Lot Size | 20.95 AC |
| Property Type | Land | Opportunity Zone |
Yes
|
| Sale Type | Investment |
| No. Lots | 1 |
| Property Type | Land |
| Property Subtype | Commercial |
| Total Lot Size | 20.95 AC |
| Opportunity Zone |
Yes |
1 Lot Available
Lot
| Lot Size | 20.95 AC |
| Lot Size | 20.95 AC |
Call 573-906-2393 for information.
Description
The site at 2110 Southern Expressway spans approximately 18.40 acres in Cape Girardeau, Missouri. It is located adjacent to Kingshighway and Southern Expressway, offering direct access to Interstate 55 and Highway 74. Utility infrastructure (water, electric, sewer) is established, and subdivision potential provides development flexibility. This property sits within a strong trade corridor characterized by mixed commercial development and planned growth initiatives.
1 1
Somewhat walkable
30/100
Exceptionally drivable
100/100
Somewhat bikeable
20/100
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2110 Southern Expressway
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