2117 & 2121 Guess Road 2 Office Properties in Durham, NC

2117 and 2121 Guess Road offer a rare opportunity to acquire one or two freestanding, owner-user– oriented commercial buildings positioned at a highly visible five-point intersection in North Durham, one of the area’s most established and supply-constrained commercial corridors.Both buildings feature immaculate, fully turnkey interiors following substantial renovations completed in 2022, with consistent, high-quality finishes throughout the portfolio. The properties are currently zoned OI with future land use guidance toward CX-3, providing long-term flexibility for a broad range of commercial uses and positioning the assets for both immediate occupancy and future redevelopment or repositioning.
Located just minutes from Duke University, Downtown Durham, I-85, and Highway 15-501, the properties benefit from excellent regional connectivity and proximity to Durham’s major employment, healthcare, and academic anchors.