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Highlights

  • Strategically located at the entrance to the Texas Medical Center, the world’s largest medical complex.
  • Easy access to area public transit, major highways, and Houston’s Inner Loop destinations.

All Available Spaces(5)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste Tenant Space 1
  • 18,223 SF
  • 5-20 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Retail
  • Partial Build-Out
  • Now

Now available for lease: 18,223 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Partially Built-Out as Standard Retail Space
  • Fits 46 - 146 People
  • 2nd Floor, Ste Tenant Space 3
  • 17,220 SF
  • 5-20 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Retail
  • Partial Build-Out
  • Now

Now available for lease: 17,220 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Partially Built-Out as Standard Retail Space
  • Fits 44 - 138 People
  • 3rd Floor, Ste Tenant Space 4
  • 19,240 SF
  • 5-20 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Retail
  • Partial Build-Out
  • Now

Now available for lease: 19,240 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Partially Built-Out as Standard Retail Space
  • Fits 49 - 154 People
  • 4th Floor, Ste Tenant Space 5
  • 3,538 SF
  • 5-20 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Retail
  • Partial Build-Out
  • Now

Now available for lease: 3,538 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Partially Built-Out as Standard Retail Space
  • Fits 9 - 29 People
  • 9th Floor, Ste 900
  • 9,363 SF
  • 5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Now available for lease: 9,363 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 12 Private Offices
  • 12 Workstations
  • Fully Built-Out as Standard Office
  • Fits 24 - 75 People
  • 1 Conference Room
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste Tenant Space 1 18,223 SF 5-20 Years Upon Request Upon Request Upon Request Upon Request Office/Retail Partial Build-Out Now
2nd Floor, Ste Tenant Space 3 17,220 SF 5-20 Years Upon Request Upon Request Upon Request Upon Request Office/Retail Partial Build-Out Now
3rd Floor, Ste Tenant Space 4 19,240 SF 5-20 Years Upon Request Upon Request Upon Request Upon Request Office/Retail Partial Build-Out Now
4th Floor, Ste Tenant Space 5 3,538 SF 5-20 Years Upon Request Upon Request Upon Request Upon Request Office/Retail Partial Build-Out Now
9th Floor, Ste 900 9,363 SF 5 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

1st Floor, Ste Tenant Space 1

Size
18,223 SF
Term
5-20 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Retail
Build-Out
Partial Build-Out
Available
Now

2nd Floor, Ste Tenant Space 3

Size
17,220 SF
Term
5-20 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Retail
Build-Out
Partial Build-Out
Available
Now

3rd Floor, Ste Tenant Space 4

Size
19,240 SF
Term
5-20 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Retail
Build-Out
Partial Build-Out
Available
Now

4th Floor, Ste Tenant Space 5

Size
3,538 SF
Term
5-20 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Retail
Build-Out
Partial Build-Out
Available
Now

9th Floor, Ste 900

Size
9,363 SF
Term
5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste Tenant Space 1

Size 18,223 SF
Term 5-20 Years
Rental Rate Upon Request
Space Use Office/Retail
Build-Out Partial Build-Out
Available Now

Now available for lease: 18,223 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Partially Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 46 - 146 People

2nd Floor, Ste Tenant Space 3

Size 17,220 SF
Term 5-20 Years
Rental Rate Upon Request
Space Use Office/Retail
Build-Out Partial Build-Out
Available Now

Now available for lease: 17,220 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Partially Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 44 - 138 People

3rd Floor, Ste Tenant Space 4

Size 19,240 SF
Term 5-20 Years
Rental Rate Upon Request
Space Use Office/Retail
Build-Out Partial Build-Out
Available Now

Now available for lease: 19,240 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Partially Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 49 - 154 People

4th Floor, Ste Tenant Space 5

Size 3,538 SF
Term 5-20 Years
Rental Rate Upon Request
Space Use Office/Retail
Build-Out Partial Build-Out
Available Now

Now available for lease: 3,538 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Partially Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 9 - 29 People

9th Floor, Ste 900

Size 9,363 SF
Term 5 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Now available for lease: 9,363 square feet of premier office/medical space located within the renowned Life Science Plaza in Houston’s Texas Medical Center area. This highly sought-after location offers a modern, flexible layout ideal for a variety of medical, research, or professional office uses.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 24 - 75 People
  • 12 Private Offices
  • 1 Conference Room
  • 12 Workstations

Property Overview

Located at the entry point to the Texas Medical Center, 2130 West Holcombe Blvd is a Class A life science and clinical office tower designed to meet the needs of leading healthcare, research, and biotechnology organizations. This prominent property offers nine floors of premium laboratory, medical, and professional office space, featuring a sleek glass façade that provides exceptional visibility along West Holcombe Boulevard. The building is strategically positioned within Houston’s world-renowned medical district, ensuring convenient access to top hospitals, research institutions, and a dense concentration of healthcare professionals. Tenants enjoy proximity to rail transit, major roadways, and Houston’s urban core, offering seamless connectivity for local and regional commuters. Amenities include secure structured parking, advanced building systems, and infrastructure tailored for clinical and laboratory functions.

  • 24 Hour Access
  • Controlled Access
  • Fitness Center
  • Property Manager on Site
  • Restaurant
  • Security System
  • Wheelchair Accessible
  • Car Charging Station
  • Air Conditioning
  • Smoke Detector

Property Facts

Building Type
Office
Year Built
2009
LoopNet Rating
4 Star
Building Height
12 Stories
Building Size
396,270 SF
Building Class
A
Typical Floor Size
26,575 SF
Parking
20 Surface Parking Spaces
855 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 12th
  • Life Science Plaza
  • Real Estate
  • Multiple
  • MD Anderson Cancer Center
  • Health Care and Social Assistance
  • 1st
  • Murphy's Deli
  • Accommodation and Food Services
  • 10th
  • Oncology Consultants
  • Health Care and Social Assistance

Sustainability

LEED Certified
Gold
LEED certification is a globally recognized symbol of sustainability achievement.

Sustainability

LEED Certification Developed by the U.S. Green Building Council (USGBC), the Leadership in Energy and Environmental Design (LEED) is a green building certification program focused on the design, construction, operation, and maintenance of green buildings, homes, and neighborhoods, which aims to help building owners and operators be environmentally responsible and use resources efficiently. LEED certification is a globally recognized symbol of sustainability achievement and leadership. To achieve LEED certification, a project earns points by adhering to prerequisites and credits that address carbon, energy, water, waste, transportation, materials, health and indoor environmental quality. Projects go through a verification and review process and are awarded points that correspond to a level of LEED certification: Platinum (80+ points) Gold (60-79 points) Silver (50-59 points) Certified (40-49 points)

Attachments

Fyler
Very walkable
80/100
Very drivable
80/100
Strong public transit
80/100
Very bikeable
80/100
  • Listing ID: 35606260

  • Date on Market: 4/23/2025

  • Last Updated:

  • Address: 2130 W Holcombe Blvd, Houston, TX 77030

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