Downtown Roanoke Mixed Use 22 Campbell Ave SE 4,400 SF Retail Building Roanoke, VA 24011 $799,000 ($181.59/SF)

Strategically positioned in the midst of vibrant Downtown Roanoke, this two-unit, 4,400 SF building seamlessly blends historic charm with modern convenience and presents an exceptional opportunity for investors. As Downtown Roanoke is home to more than 900 businesses and 2600 residents, 22 Campbell Avenue SE is accessible and highly visible. The glass-front first floor is configured as a modern street-level retail space and is available for new lease and occupancy as of September 1, 2026.
The second floor has been renovated into an attractive, modern 2bd/2bth residence (2021) and is available for new occupancy as of February 1, 2026. Recessed lighting, granite and hardwoods throughout, with the potential to develop a rooftop deck. Striking, large windows overlook Campbell Avenue and flood the main living area with ambient light. Each spacious bedroom is endowed with an en suite full bathroom, and the primary bedroom with a generous closet. Preferential parking available through PARK Roanoke's Residential Parking Programs.
The building is fully sprinklered and houses an existing freight elevator.
22 Campbell Avenue SE presents a sleek and sophisticated investment prospect for an owner-resident seeking supplemental income to offset living expenses or for anyone looking to diversify a portfolio.
Immersed in a walkable array of local restaurant, retail, and cultural venues, 22 Campbell Avenue's central position in the Historic Roanoke City Market area amplifies its intrinsic curb appeal. Notable nearby destinations include Frankie Rowland's Steakhouse, Alexander's, a variety of ethnic cuisines, independent galleries, The City Market Building, The Taubman Museum of Art, and Elmwood Park.
Immediately across the street lies the iconic Center In the Square, home to the Mill Mountain Theatre, The Science Museum of Western Virginia, Kids Square, Six and Sky Roof Top Grille and other attractions.
A few paces beyond Center in the Square, the vendors of the beloved Farmers Market line the covered walkway of Market Square to offer locally grown fruits, vegetables, flowers, plants, meats, cheeses, baked goods, and hand-crafted items.
In every direction, a pulsing, vital downtown ecosystem beckons and promises to support 22 Campbell Avenue's next occupants.
Convenient to US 220, US 460, I-581 and I-81 and only 10 minutes from the Roanoke-Blacksburg Regional Airport.