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Highlights

  • Positioned in the heart of Santee Alley, a popular tourist destination, and a hub for retail, fashion, and culture for the local community.
  • 221 East 12th Street is situated in a highly accessible location, close to multiple highways and commuter rail, as well as transit lines.
  • Call to find out about our exclusive leasing specials.
  • Conveniently located in one of the most sought-after areas, with excellent visibility, heavy foot traffic, and a high spending environment.
  • Flexible layout to meet tenant needs, providing the ability to join a synergistic location that encourages cross-shopping.

All Available Spaces(7)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste 1
  • 520 SF
  • Negotiable
  • $21.00 /SF/YR $1.75 /SF/MO $10,920 /YR $910.00 /MO
  • Office
  • Spec Suite
  • Now

The private garage space offers the perfect solution for enjoying the convenience of parking inside the building with direct, hassle-free vehicle access. Approximately 520 square feet of private parking space is available for lease. Lessee of the private garage must be a tenant currently renting one of the units and seeking to rent an additional private garage space.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fits 2 - 5 People
  • Convenient indoor parking
  • Open floor plan layout
  • Open Floor Plan Layout
  • Space is in Excellent Condition
  • Space is in excellent conditoin
  • Easy & direct access to the building
  • 2nd Floor, Ste 203
  • 609 SF
  • Negotiable
  • $19.80 /SF/YR $1.65 /SF/MO $12,058 /YR $1,005 /MO
  • Office/Medical
  • Partial Build-Out
  • Now

Located in a highly desirable area with excellent visibility and steady foot traffic, this versatile second-floor space offers endless possibilities. The open layout can easily be customized to suit your business needs—whether for retail, office, or studio use. Large windows provide abundant natural light, creating a bright and welcoming environment for customers and staff alike. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Fits 2 - 5 People
  • Central Air and Heating
  • Natural Light
  • Office intensive layout
  • Space is in Excellent Condition
  • High Ceilings
  • 2nd Floor, Ste 204
  • 624 SF
  • Negotiable
  • $19.80 /SF/YR $1.65 /SF/MO $12,355 /YR $1,030 /MO
  • Office/Retail
  • Full Build-Out
  • Now

Located on the second floor, this open and bright space features its own sink and private shower. The layout is versatile and ideal for a wide range of uses, including: Hair stylists and barbers, Estheticians and skincare studios, Massage therapy, Wellness or treatment rooms, Tattoo artists, Beauty professionals, Flexible setup, great natural light, and move-in ready. Perfect for service-based businesses looking for privacy and convenience. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Flexible space ideal for office or retail use.
  • Perfect for a variety of retail and office uses.
  • Abundant street parking.
  • Fully Built-Out as Standard Office
  • Fits 2 - 5 People
  • Parking space available for monthly rent.
  • Modern, bright with access to two elevators.
  • 2nd Floor, Ste 205
  • 623 SF
  • Negotiable
  • $19.80 /SF/YR $1.65 /SF/MO $12,335 /YR $1,028 /MO
  • Office/Retail
  • Full Build-Out
  • Now

Located in a highly desirable area with excellent visibility and steady foot traffic, this versatile second-floor space offers endless possibilities. The open layout can easily be customized to suit your business needs—whether for retail, office, or studio use. Large windows provide abundant natural light, creating a bright and welcoming environment for customers and staff alike. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Flexible space ideal for office or retail use.
  • Perfect for a variety of retail and office uses.
  • Abundant street parking.
  • Fully Built-Out as Standard Office
  • Fits 2 - 5 People
  • Parking space available for monthly rent.
  • Modern, bright with access to two elevators.
  • 3rd Floor, Ste 300
  • 1,900 SF
  • Negotiable
  • $21.60 /SF/YR $1.80 /SF/MO $41,040 /YR $3,420 /MO
  • Office/Retail
  • Full Build-Out
  • Now

Located in a highly desirable area with excellent visibility and strong foot traffic, this third-floor corner suite features multiple private offices, a conference room, reception and waiting areas, and a kitchen with counter, sink, and built-in cabinets for storage. The functional layout is ideal for creating an efficient and professional environment for staff and clients. Perfect for CPA, tax, real estate, legal, consulting, or medical offices, this versatile space offers privacy, convenience, and a professional atmosphere in one of the area’s most sought-after commercial locations. A must-see office space—call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Conference Rooms
  • Central Air and Heating
  • Private Restrooms
  • Ideal space for a variety of business needs.
  • Fully Built-Out as Standard Retail Space
  • Fits 5 - 16 People
  • Space is in Excellent Condition
  • Reception Area
  • Sleek and contemporary building that stands out.
  • Abundant street parking.
  • 3rd Floor, Ste 304
  • 239 SF
  • Negotiable
  • $23.40 /SF/YR $1.95 /SF/MO $5,593 /YR $466.05 /MO
  • Office/Retail
  • Full Build-Out
  • Now

This bright open space is well-lit office space on the third floor offers a perfect setting for businesses looking to make a lasting impression. A bright, welcoming atmosphere, designed to inspire productivity and creativity. A flexible layout, ideal for a variety of business types, and ready to accommodate your unique needs. With its professional environment and convenient location, this space is the ideal choice for businesses seeking a functional and impressive workplace.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Space is in Excellent Condition
  • Natural Light
  • Excellent mix of tenants.
  • Recently renovated lobby and elevators.
  • Fully Built-Out as Standard Retail Space
  • Fits 1 - 2 People
  • High Ceilings
  • Open-Plan
  • Perfect for a variety of retail and office uses.
  • Abundant street parking.
  • 3rd Floor, Ste 307
  • 1,142 SF
  • Negotiable
  • $22.80 /SF/YR $1.90 /SF/MO $26,038 /YR $2,170 /MO
  • Office/Retail
  • Full Build-Out
  • Now

This spacious third-floor corner unit offers a versatile open floor plan, providing unlimited potential for customization to suit your business needs. The flexible layout can be used to create individual workstations, partitioned offices, or an expansive, collaborative environment; this unit can accommodate it all. Featuring an abundance of natural light, the space creates an inviting and vibrant atmosphere, fostering productivity and creativity. It is ideal for businesses seeking a flexible, high-quality workspace that can adapt to their unique requirements.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • High Ceilings
  • Open-Plan
  • A bright, welcoming atmosphere.
  • Abundant street parking.
  • Fully Built-Out as Standard Retail Space
  • Fits 3 - 10 People
  • Natural Light
  • Easy elevator access for added convenience.
  • Open Floor plan with endless possibilities.
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste 1 520 SF Negotiable $21.00 /SF/YR $1.75 /SF/MO $10,920 /YR $910.00 /MO Office Spec Suite Now
2nd Floor, Ste 203 609 SF Negotiable $19.80 /SF/YR $1.65 /SF/MO $12,058 /YR $1,005 /MO Office/Medical Partial Build-Out Now
2nd Floor, Ste 204 624 SF Negotiable $19.80 /SF/YR $1.65 /SF/MO $12,355 /YR $1,030 /MO Office/Retail Full Build-Out Now
2nd Floor, Ste 205 623 SF Negotiable $19.80 /SF/YR $1.65 /SF/MO $12,335 /YR $1,028 /MO Office/Retail Full Build-Out Now
3rd Floor, Ste 300 1,900 SF Negotiable $21.60 /SF/YR $1.80 /SF/MO $41,040 /YR $3,420 /MO Office/Retail Full Build-Out Now
3rd Floor, Ste 304 239 SF Negotiable $23.40 /SF/YR $1.95 /SF/MO $5,593 /YR $466.05 /MO Office/Retail Full Build-Out Now
3rd Floor, Ste 307 1,142 SF Negotiable $22.80 /SF/YR $1.90 /SF/MO $26,038 /YR $2,170 /MO Office/Retail Full Build-Out Now

1st Floor, Ste 1

Size
520 SF
Term
Negotiable
Rental Rate
$21.00 /SF/YR $1.75 /SF/MO $10,920 /YR $910.00 /MO
Space Use
Office
Build-Out
Spec Suite
Available
Now

2nd Floor, Ste 203

Size
609 SF
Term
Negotiable
Rental Rate
$19.80 /SF/YR $1.65 /SF/MO $12,058 /YR $1,005 /MO
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

2nd Floor, Ste 204

Size
624 SF
Term
Negotiable
Rental Rate
$19.80 /SF/YR $1.65 /SF/MO $12,355 /YR $1,030 /MO
Space Use
Office/Retail
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 205

Size
623 SF
Term
Negotiable
Rental Rate
$19.80 /SF/YR $1.65 /SF/MO $12,335 /YR $1,028 /MO
Space Use
Office/Retail
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 300

Size
1,900 SF
Term
Negotiable
Rental Rate
$21.60 /SF/YR $1.80 /SF/MO $41,040 /YR $3,420 /MO
Space Use
Office/Retail
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 304

Size
239 SF
Term
Negotiable
Rental Rate
$23.40 /SF/YR $1.95 /SF/MO $5,593 /YR $466.05 /MO
Space Use
Office/Retail
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 307

Size
1,142 SF
Term
Negotiable
Rental Rate
$22.80 /SF/YR $1.90 /SF/MO $26,038 /YR $2,170 /MO
Space Use
Office/Retail
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste 1

Size 520 SF
Term Negotiable
Rental Rate $21.00 /SF/YR
Space Use Office
Build-Out Spec Suite
Available Now

The private garage space offers the perfect solution for enjoying the convenience of parking inside the building with direct, hassle-free vehicle access. Approximately 520 square feet of private parking space is available for lease. Lessee of the private garage must be a tenant currently renting one of the units and seeking to rent an additional private garage space.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open Floor Plan Layout
  • Fits 2 - 5 People
  • Space is in Excellent Condition
  • Convenient indoor parking
  • Space is in excellent conditoin
  • Open floor plan layout
  • Easy & direct access to the building

2nd Floor, Ste 203

Size 609 SF
Term Negotiable
Rental Rate $19.80 /SF/YR
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Located in a highly desirable area with excellent visibility and steady foot traffic, this versatile second-floor space offers endless possibilities. The open layout can easily be customized to suit your business needs—whether for retail, office, or studio use. Large windows provide abundant natural light, creating a bright and welcoming environment for customers and staff alike. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Office intensive layout
  • Fits 2 - 5 People
  • Space is in Excellent Condition
  • Central Air and Heating
  • High Ceilings
  • Natural Light

2nd Floor, Ste 204

Size 624 SF
Term Negotiable
Rental Rate $19.80 /SF/YR
Space Use Office/Retail
Build-Out Full Build-Out
Available Now

Located on the second floor, this open and bright space features its own sink and private shower. The layout is versatile and ideal for a wide range of uses, including: Hair stylists and barbers, Estheticians and skincare studios, Massage therapy, Wellness or treatment rooms, Tattoo artists, Beauty professionals, Flexible setup, great natural light, and move-in ready. Perfect for service-based businesses looking for privacy and convenience. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout
  • Fits 2 - 5 People
  • Flexible space ideal for office or retail use.
  • Parking space available for monthly rent.
  • Perfect for a variety of retail and office uses.
  • Modern, bright with access to two elevators.
  • Abundant street parking.

2nd Floor, Ste 205

Size 623 SF
Term Negotiable
Rental Rate $19.80 /SF/YR
Space Use Office/Retail
Build-Out Full Build-Out
Available Now

Located in a highly desirable area with excellent visibility and steady foot traffic, this versatile second-floor space offers endless possibilities. The open layout can easily be customized to suit your business needs—whether for retail, office, or studio use. Large windows provide abundant natural light, creating a bright and welcoming environment for customers and staff alike. Don’t miss this opportunity to establish your business in one of the area’s most sought-after locations. Call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout
  • Fits 2 - 5 People
  • Flexible space ideal for office or retail use.
  • Parking space available for monthly rent.
  • Perfect for a variety of retail and office uses.
  • Modern, bright with access to two elevators.
  • Abundant street parking.

3rd Floor, Ste 300

Size 1,900 SF
Term Negotiable
Rental Rate $21.60 /SF/YR
Space Use Office/Retail
Build-Out Full Build-Out
Available Now

Located in a highly desirable area with excellent visibility and strong foot traffic, this third-floor corner suite features multiple private offices, a conference room, reception and waiting areas, and a kitchen with counter, sink, and built-in cabinets for storage. The functional layout is ideal for creating an efficient and professional environment for staff and clients. Perfect for CPA, tax, real estate, legal, consulting, or medical offices, this versatile space offers privacy, convenience, and a professional atmosphere in one of the area’s most sought-after commercial locations. A must-see office space—call today to learn about current leasing specials!

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 5 - 16 People
  • Conference Rooms
  • Space is in Excellent Condition
  • Central Air and Heating
  • Reception Area
  • Private Restrooms
  • Sleek and contemporary building that stands out.
  • Ideal space for a variety of business needs.
  • Abundant street parking.

3rd Floor, Ste 304

Size 239 SF
Term Negotiable
Rental Rate $23.40 /SF/YR
Space Use Office/Retail
Build-Out Full Build-Out
Available Now

This bright open space is well-lit office space on the third floor offers a perfect setting for businesses looking to make a lasting impression. A bright, welcoming atmosphere, designed to inspire productivity and creativity. A flexible layout, ideal for a variety of business types, and ready to accommodate your unique needs. With its professional environment and convenient location, this space is the ideal choice for businesses seeking a functional and impressive workplace.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 1 - 2 People
  • Space is in Excellent Condition
  • High Ceilings
  • Natural Light
  • Open-Plan
  • Excellent mix of tenants.
  • Perfect for a variety of retail and office uses.
  • Recently renovated lobby and elevators.
  • Abundant street parking.

3rd Floor, Ste 307

Size 1,142 SF
Term Negotiable
Rental Rate $22.80 /SF/YR
Space Use Office/Retail
Build-Out Full Build-Out
Available Now

This spacious third-floor corner unit offers a versatile open floor plan, providing unlimited potential for customization to suit your business needs. The flexible layout can be used to create individual workstations, partitioned offices, or an expansive, collaborative environment; this unit can accommodate it all. Featuring an abundance of natural light, the space creates an inviting and vibrant atmosphere, fostering productivity and creativity. It is ideal for businesses seeking a flexible, high-quality workspace that can adapt to their unique requirements.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Retail Space
  • Open Floor Plan Layout
  • Fits 3 - 10 People
  • High Ceilings
  • Natural Light
  • Open-Plan
  • Easy elevator access for added convenience.
  • A bright, welcoming atmosphere.
  • Open Floor plan with endless possibilities.
  • Abundant street parking.

Matterport 3D Tour

Suite 300

Property Overview

Presenting a rare opportunity to lease up to 29,654 square feet of prime commercial space in the heart of Los Angeles’ iconic Fashion District. Located at 221 East 12th Street, this contemporary corner building sits at the nexus of Santee Alley, a vibrant hub for fashion, retail, and culture, offering unmatched visibility and exposure between two signalized intersections. The property is ideal for boutique retail concepts, creative studios, salons, galleries, professional offices, or restaurant ventures seeking to thrive in a high-traffic, affluent area. This dynamic mixed-use space features expansive storefronts with abundant natural light, modern industrial finishes, and full 24/7 access. Tenants benefit from premium signage opportunities, additional storage availability, and proximity to multiple major thoroughfares. The location is less than 30 minutes from both the Los Angeles International Airport and the Bob Hope Airport, ensuring regional and national connectivity. 221 East 12th Street is also in proximity to many major tourist locations like Crypto.com Arena, formerly known as the Staples Center, home to the Los Angeles Lakers, the Los Angeles Convention Center, and the GRAMMY museum, drawing in additional foot traffic to the area. Positioned in one of LA’s most sought-after neighborhoods, the property enjoys direct access to the city’s ever-expanding public transportation network, including commuter rail and transit lines. With over 1,200,000 people in a 5-mile radius and total consumer spending exceeding $10.8 million, this location offers unparalleled access to a qualified customer base and workforce. The site is exposed to more than 11,000 vehicles per day, maximizing brand visibility and foot traffic. Downtown Los Angeles continues to attract tenants due to its proximity to clients, infrastructure, and ability to draw talent from across the region. The Fashion District itself spans over 100 blocks and is globally recognized as a center for fashion, textiles, and design. Businesses here benefit from a dynamic ecosystem of high-end showrooms, wholesale apparel vendors, and cutting-edge design studios. Whether launching a flagship retail store, establishing a creative headquarters, or opening a destination restaurant, 221 East 12th Street offers flexibility, exposure, and location to elevate a brand in one of Los Angeles' most energetic and influential districts. Call to find out about our exclusive leasing specials!

Property Facts

Building Type
Office
Year Built
1989
Building Height
4 Stories
Building Size
29,654 SF
Building Class
C
Typical Floor Size
8,625 SF
Parking
Surface Parking
Covered Parking
Reserved Parking
Exceptionally walkable
100/100
Very drivable
80/100
Exceptional public transit
100/100
Moderately bikeable
70/100
  • Listing ID: 34007854

  • Date on Market: 11/26/2025

  • Last Updated:

  • Address: 221 E 12th St, Los Angeles, CA 90015

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