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Highlights

  • Located within an Opportunity Zone with significant tax incentive advantages
  • Strong visibility with over 35,000 vehicles per day along E 105th Street
  • Zoned NX3 Neighborhood Flex 3, supporting versatile development options
  • Positioned adjacent to Cleveland Clinic Main Campus and within walking distance to University Circle
  • Proximity to Meijer Fairfax Market, educational institutions, and cultural attractions
  • Dense surrounding market with a population of over 136,000 within a 3-mile radius

LOT Available

Display Rental Rate as

Rental Rate
  • Upon Request
  • Upon Request
  • Upon Request
  • Upon Request
Lease Term Negotiable
Lot Size 0.69 AC

Available for ground lease or build-to-suit, this 0.69-acre site offers exceptional positioning for businesses seeking proximity to Cleveland Clinic, the largest employer in Northeast Ohio, and the thriving University Circle district. The location is ideal for medical office, retail, or mixed-use development, offering high traffic counts and strong connectivity.

The property sits along the Opportunity Corridor with swift access to major thoroughfares, downtown Cleveland (4 miles away), and key regional employers. Surrounded by dense residential neighborhoods and daily traffic generated by Cleveland Clinic, University Hospitals, and Case Western Reserve, the site promises built-in demand for healthcare, hospitality, and service-related uses. Flexible zoning further enhances its appeal for a wide range of commercial applications.

Property Overview

The property is a 0.69-acre parcel on E 105th Street in Cleveland, Ohio, zoned NX3 Neighborhood Flex 3. It is adjacent to the Cleveland Clinic Main Campus and close to University Circle. Traffic counts on E 105th Street exceed 35,000 vehicles per day. Nearby amenities include the Meijer Fairfax Market and educational institutions such as Case Western Reserve University. The area is served by major roads, including the Opportunity Corridor, and is approximately four miles from downtown Cleveland.

Property Facts

Total Space Available 0.69 AC
Property Type Land
Property Subtype Commercial
Proposed Use Commercial
Very walkable
80/100
Moderately drivable
60/100
Good public transit
60/100
Moderately bikeable
60/100
  • Listing ID: 40481317

  • Date on Market: 5/11/2026

  • Last Updated:

  • Address: 2220 105th st, Cleveland, OH 44106

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