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Sublease Highlights

  • 5-story Central Downtown Office Building located at the corner of Centre and Canal Street
  • Featuring Institutional tenants within the building
  • Perfectly positioned in New York's most exclusive downtown shopping district, surrounded by restaurants, cafes, and retail stores.
  • Providing easy access to all subway lines such as 6, N, Q, R, W, B, D, J, Z, A, C, E

All Available Spaces(2)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 3rd Floor, Ste 3
  • 7,000 SF
  • Dec 2033
  • $60.00 /SF/YR $5.00 /SF/MO $420,000 /YR $35,000 /MO
  • Office/Medical
  • Full Build-Out
  • September 01, 2026

168 Centre 7,000 SF Fully Built-Out Floor-through Office Space for Lease in Prime Canal Street Corridor. Available for immediate sublease: an entire, fully built-out 7,000 SF floor at 168 Centre Street, situated directly on the Canal Street corridor bridging TriBeCa, SoHo, Little Italy, and Chinatown. This turnkey space is move-in ready and features a mix of high-density workstations and private executive suites, a large tech-enabled conference room seating 20+, a fully built-out wet pantry with stainless steel appliances, private restrooms with modern finishes, and multiple dedicated storage rooms. Expansive wrap-around windows deliver sweeping, unobstructed skyline and city views — from Chinatown's pagoda rooflines to the Lower Manhattan skyline beyond — with ceiling heights up to 12 feet. The building offers 24/7 access through a modern, double-elevator lobby with Johnson Controls key-fob security, and is home to a roster of premium institutional and medical tenants including Rendr, SoHo Ambulatory Surgical Center, and Mount Sinai Doctors — providing excellent co-tenancy and building prestige for a professional office user. Located moments from the NYC Civic Center and Courthouses, Charles B. Wang Community Health Center, Roxy Hotel, and 11 Howard, with acclaimed neighborhood retail and dining nearby including Alexander Wang, Ganni, La Mercerie, Frenchette, and Balthazar — this address puts tenants at the nexus of some of Manhattan's most dynamic submarkets.

  • Sublease space available from current tenant
  • Fully Built-Out as Standard Office
  • Fits 18 - 56 People
  • 1 Conference Room
  • Finished Ceilings: 9’8” - 10’2”
  • Reception Area
  • Elevator Access
  • Wi-Fi Connectivity
  • Fully Carpeted
  • Plug & Play
  • High Ceilings
  • Natural Light
  • Emergency Lighting
  • Demised WC facilities
  • Wheelchair Accessible
  • Move in Ready
  • Listed rate may not include certain utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 4 Private Offices
  • 49 Workstations
  • Space is in Excellent Condition
  • Central Air and Heating
  • Private Restrooms
  • Print/Copy Room
  • Security System
  • Corner Space
  • Drop Ceilings
  • After Hours HVAC Available
  • DDA Compliant
  • Smoke Detector
  • Skyline Views of TriBeca, SoHo, and FiDi
  • Entire Floor
  • 4th Floor, Ste 3M
  • 3,500 SF
  • Dec 2033
  • $65.00 /SF/YR $5.42 /SF/MO $227,500 /YR $18,958 /MO
  • Office/Medical
  • Full Build-Out
  • September 01, 2026

168 Centre Street, Suite 3M | 3,500 SF Turnkey Office / Medical Space Suite 3M offers 3,500 SF of move-in ready, turnkey commercial space positioned at the intersection of SoHo, TriBeCa, and Chinatown. Featuring 10-foot ceilings, accent soffit lighting, and high-density executive infrastructure, this suite is ideally suited for medical practices, professional services, or corporate administrative headquarters. Suite Highlights as follows: Private Offices: Configured with 6 dedicated private offices/consultation rooms featuring glass-front entry doors. Open Work Area: Spacious open central layout suitable for reception, workstation pods, or collaborative space. Natural Light & Views: Expansive wrap-around window line providing high natural light exposure and views overlooking the Canal Street corridor. Wet Pantry & Storage: Includes a fully built-out wet pantry with counter space and sink, plus dedicated internal storage rooms. Restroom Access: Shared floor restrooms co-located on the floor with Mount Sinai Doctors. Building Amenities & Lease Details as follows: Lease Term: Flexible 3 to 7-year sublease term with immediate possession. Access & Security: 24/7 key fob access control system (Johnson Controls) and dual passenger elevator access. Institutional Co-Tenancy: Establish a presence alongside major medical groups, including Mount Sinai Doctors, Rendr, and SoHo Ambulatory Surgical Center. Transit Access: Direct proximity to the Canal Street subway complex (6, N, Q, R, W, J, Z, A, C, E lines).

  • Sublease space available from current tenant
  • Fully Built-Out as Standard Office
  • Fits 10 - 35 People
  • 1 Conference Room
  • Space is in Excellent Condition
  • Wi-Fi Connectivity
  • Fully Carpeted
  • Plug & Play
  • Natural Light
  • Common Parts WC Facilities
  • Open-Plan
  • Wheelchair Accessible
  • Fully Built Out
  • Listed rate may not include certain utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 6 Private Offices
  • Finished Ceilings: 9’7” - 10’1”
  • Central Air and Heating
  • Print/Copy Room
  • Security System
  • Corner Space
  • After Hours HVAC Available
  • DDA Compliant
  • Smoke Detector
  • Downtown TriBeca, SoHo, FiDi Skyline Views
  • Move in Ready
Space Size Term Rental Rate Space Use Build-Out Available
3rd Floor, Ste 3 7,000 SF Dec 2033 $60.00 /SF/YR $5.00 /SF/MO $420,000 /YR $35,000 /MO Office/Medical Full Build-Out September 01, 2026
4th Floor, Ste 3M 3,500 SF Dec 2033 $65.00 /SF/YR $5.42 /SF/MO $227,500 /YR $18,958 /MO Office/Medical Full Build-Out September 01, 2026

3rd Floor, Ste 3

Size
7,000 SF
Term
Dec 2033
Rental Rate
$60.00 /SF/YR $5.00 /SF/MO $420,000 /YR $35,000 /MO
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
September 01, 2026

4th Floor, Ste 3M

Size
3,500 SF
Term
Dec 2033
Rental Rate
$65.00 /SF/YR $5.42 /SF/MO $227,500 /YR $18,958 /MO
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
September 01, 2026

3rd Floor, Ste 3

Size 7,000 SF
Term Dec 2033
Rental Rate $60.00 /SF/YR
Space Use Office/Medical
Build-Out Full Build-Out
Available September 01, 2026

168 Centre 7,000 SF Fully Built-Out Floor-through Office Space for Lease in Prime Canal Street Corridor. Available for immediate sublease: an entire, fully built-out 7,000 SF floor at 168 Centre Street, situated directly on the Canal Street corridor bridging TriBeCa, SoHo, Little Italy, and Chinatown. This turnkey space is move-in ready and features a mix of high-density workstations and private executive suites, a large tech-enabled conference room seating 20+, a fully built-out wet pantry with stainless steel appliances, private restrooms with modern finishes, and multiple dedicated storage rooms. Expansive wrap-around windows deliver sweeping, unobstructed skyline and city views — from Chinatown's pagoda rooflines to the Lower Manhattan skyline beyond — with ceiling heights up to 12 feet. The building offers 24/7 access through a modern, double-elevator lobby with Johnson Controls key-fob security, and is home to a roster of premium institutional and medical tenants including Rendr, SoHo Ambulatory Surgical Center, and Mount Sinai Doctors — providing excellent co-tenancy and building prestige for a professional office user. Located moments from the NYC Civic Center and Courthouses, Charles B. Wang Community Health Center, Roxy Hotel, and 11 Howard, with acclaimed neighborhood retail and dining nearby including Alexander Wang, Ganni, La Mercerie, Frenchette, and Balthazar — this address puts tenants at the nexus of some of Manhattan's most dynamic submarkets.

  • Sublease space available from current tenant
  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 18 - 56 People
  • 4 Private Offices
  • 1 Conference Room
  • 49 Workstations
  • Finished Ceilings: 9’8” - 10’2”
  • Space is in Excellent Condition
  • Reception Area
  • Central Air and Heating
  • Elevator Access
  • Private Restrooms
  • Wi-Fi Connectivity
  • Print/Copy Room
  • Fully Carpeted
  • Security System
  • Plug & Play
  • Corner Space
  • High Ceilings
  • Drop Ceilings
  • Natural Light
  • After Hours HVAC Available
  • Emergency Lighting
  • DDA Compliant
  • Demised WC facilities
  • Smoke Detector
  • Wheelchair Accessible
  • Skyline Views of TriBeca, SoHo, and FiDi
  • Move in Ready
  • Entire Floor

4th Floor, Ste 3M

Size 3,500 SF
Term Dec 2033
Rental Rate $65.00 /SF/YR
Space Use Office/Medical
Build-Out Full Build-Out
Available September 01, 2026

168 Centre Street, Suite 3M | 3,500 SF Turnkey Office / Medical Space Suite 3M offers 3,500 SF of move-in ready, turnkey commercial space positioned at the intersection of SoHo, TriBeCa, and Chinatown. Featuring 10-foot ceilings, accent soffit lighting, and high-density executive infrastructure, this suite is ideally suited for medical practices, professional services, or corporate administrative headquarters. Suite Highlights as follows: Private Offices: Configured with 6 dedicated private offices/consultation rooms featuring glass-front entry doors. Open Work Area: Spacious open central layout suitable for reception, workstation pods, or collaborative space. Natural Light & Views: Expansive wrap-around window line providing high natural light exposure and views overlooking the Canal Street corridor. Wet Pantry & Storage: Includes a fully built-out wet pantry with counter space and sink, plus dedicated internal storage rooms. Restroom Access: Shared floor restrooms co-located on the floor with Mount Sinai Doctors. Building Amenities & Lease Details as follows: Lease Term: Flexible 3 to 7-year sublease term with immediate possession. Access & Security: 24/7 key fob access control system (Johnson Controls) and dual passenger elevator access. Institutional Co-Tenancy: Establish a presence alongside major medical groups, including Mount Sinai Doctors, Rendr, and SoHo Ambulatory Surgical Center. Transit Access: Direct proximity to the Canal Street subway complex (6, N, Q, R, W, J, Z, A, C, E lines).

  • Sublease space available from current tenant
  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 10 - 35 People
  • 6 Private Offices
  • 1 Conference Room
  • Finished Ceilings: 9’7” - 10’1”
  • Space is in Excellent Condition
  • Central Air and Heating
  • Wi-Fi Connectivity
  • Print/Copy Room
  • Fully Carpeted
  • Security System
  • Plug & Play
  • Corner Space
  • Natural Light
  • After Hours HVAC Available
  • Common Parts WC Facilities
  • DDA Compliant
  • Open-Plan
  • Smoke Detector
  • Wheelchair Accessible
  • Downtown TriBeca, SoHo, FiDi Skyline Views
  • Fully Built Out
  • Move in Ready

Property Overview

168 Centre Street is a premier Commercial & Medical Office Building that is located at the vibrant intersection of SoHo, Chinatown, and Little Italy. 168 Centre is a boutique 5-story commercial building engineered for high-volume clinical practices, ambulatory facilities, and professional office suites. Building Highlights & Features: Renovated Main Lobby: A newly updated, contemporary lobby creates an inviting, professional entrance for patients, clients, and staff. Double Elevator Service: Equipped with dual passenger elevators to ensure efficient vertical transport and seamless access across all floors. Flexible Layouts: ~7,000 SF floor plates accommodate custom medical buildouts, private exam rooms, diagnostic suites, or modern open-plan administrative offices. Prime Transit Connectivity: Situated steps from the Canal Street transit hub, delivering immediate access to the 6, N, Q, R, W, J, and Z subway lines. Established Tenant Ecosystem: The property serves as a recognized Downtown healthcare destination, anchored by premier medical networks and specialized outpatient providers: Mount Sinai Doctors: Features comprehensive multi-specialty care suites, including Mount Sinai oncology, surgery, hepatology, and cardiology departments. SoHo Ambulatory Surgical Center (SoHo ASC): A state-of-the-art outpatient facility supporting specialized surgical procedures and gastroenterology care. Rendr & Clinical Groups: Houses independent medical practices designed to deliver accessible, multilingual healthcare tailored to the Lower Manhattan community.

  • 24 Hour Access
  • Banking
  • Controlled Access
  • Property Manager on Site
  • Security System
  • Wheelchair Accessible
  • Air Conditioning
  • Smoke Detector

Property Facts

Building Type
Office
Year Built
1920
Building Height
5 Stories
Building Size
43,942 SF
Building Class
B
Typical Floor Size
7,000 SF

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • Citizens
  • Finance and Insurance
  • 1st
  • Katherine Ni Md
  • Health Care and Social Assistance
  • 3rd
  • Mount Sinai Doctors Specialty Practice
  • Health Care and Social Assistance
  • 2nd
  • Rendr
  • Health Care and Social Assistance
  • 5th
  • SoHo Ambulatory Surgical Center
  • Health Care and Social Assistance
Exceptionally walkable
100/100
Moderately drivable
60/100
Exceptional public transit
100/100
Exceptionally bikeable
90/100
  • Listing ID: 41860160

  • Date on Market: 8/24/2026

  • Last Updated:

  • Address: 233-235 Canal St, New York, NY 10013

Contact the Leasing Agent

233-235 Canal St

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