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The Daniel Building 301 N Main St 1,345 - 5,408 SF of 4-Star Retail Space Available in Greenville, SC 29601

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HIGHLIGHTS

  • Prime lobby-level retail in Greenville’s tallest tower
  • Over 300 on-site parking spaces for tenants and visitors
  • Fully equipped wine/coffee bar and outdoor patio space
  • Renovated with hospitality-grade finishes and lighting
  • Located on Main Street with direct access to I-385 and US-29
  • Steps from Bon Secours Wellness Arena and downtown attractions

ALL AVAILABLE SPACES(2)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 300
  • 4,063 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Retail
  • Shell Space
  • Now

Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine $4 million renovation complete

  • Highly Desirable End Cap Space
  • Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine
  • Lobby level of 25-story office tower, the Daniel B
  • $4 million renovation complete
  • Abundant outdoor patio space
  • Situated on the main thoroughfares of Main Street
  • 1st Floor, Ste 304
  • 1,345 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Retail
  • Shell Space
  • Now

Suite 304: ±1,345 SF $4 million renovation complete

  • $4 million renovation complete
  • Abundant outdoor patio space
  • Situated on the main thoroughfares of Main Street
  • Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine
  • Lobby level of 25-story office tower, the Daniel B
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 300 4,063 SF Negotiable Upon Request Upon Request Upon Request Upon Request Retail Shell Space Now
1st Floor, Ste 304 1,345 SF Negotiable Upon Request Upon Request Upon Request Upon Request Retail Shell Space Now

1st Floor, Ste 300

Size
4,063 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Retail
Condition
Shell Space
Available
Now

1st Floor, Ste 304

Size
1,345 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Retail
Condition
Shell Space
Available
Now

1st Floor, Ste 300

Size 4,063 SF
Term Negotiable
Rental Rate Upon Request
Space Use Retail
Condition Shell Space
Available Now

Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine $4 million renovation complete

  • Highly Desirable End Cap Space
  • $4 million renovation complete
  • Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine
  • Abundant outdoor patio space
  • Lobby level of 25-story office tower, the Daniel B
  • Situated on the main thoroughfares of Main Street

1st Floor, Ste 304

Size 1,345 SF
Term Negotiable
Rental Rate Upon Request
Space Use Retail
Condition Shell Space
Available Now

Suite 304: ±1,345 SF $4 million renovation complete

  • $4 million renovation complete
  • Suite 300: ±3,000 SF plus ±1,063 SF Mezzanine
  • Abundant outdoor patio space
  • Lobby level of 25-story office tower, the Daniel B
  • Situated on the main thoroughfares of Main Street

PROPERTY FACTS

Building Type
Office
Year Built/Renovated
1965/2025
LoopNet Rating
4 Star
Building Height
25 Stories
Building Size
357,752 SF
Building Class
B
Typical Floor Size
13,814 SF
Unfinished Ceiling Height
13’
Parking
500 Surface Parking Spaces
400 Covered Parking Spaces

PROPERTY OVERVIEW

Positioned at the heart of Greenville’s vibrant central business district, The Daniel Building is the city’s tallest and most iconic office tower. Located at 301 North Main Street, this 25-story landmark has undergone a transformative $4 million renovation, blending timeless architecture with modern amenities. Tenants benefit from a fully equipped wine and coffee bar in the lobby, abundant outdoor patio space, and over 300 on-site parking spaces—an exceptional convenience in downtown Greenville. The property sits prominently at the intersection of Main Street and College Avenue, just 0.4 miles from Bon Secours Wellness Arena and easily accessible via I-385 and US-29. The surrounding area is a dynamic mix of office, retail, dining, and entertainment, drawing consistent foot traffic and offering strong visibility. Designed by DP3 Architects, the renovation emphasizes hospitality-inspired finishes, enhanced lighting, and a welcoming streetscape that complements the building’s stature. The Daniel Building is not only a symbol of Greenville’s growth but also a strategic location for retailers seeking prominence and accessibility.

  • Atrium
  • Banking
  • Bus Line
  • Conferencing Facility
  • Property Manager on Site
  • Restaurant
  • Signage
Walk Score®
Walker's Paradise (90)
Bike Score®
Very Bikeable (84)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®

NEARBY MAJOR RETAILERS

Anytime Fitness
Charles Schwab
Truist
Ameris Bank
Tupelo Honey
Maple Street Biscuit Company
First Citizens Bank
SouthState Bank
Moe's Original BBQ
Carolina Ale House
  • Listing ID: 37720846

  • Date on Market: 9/18/2025

  • Last Updated:

  • Address: 301 N Main St, Greenville, SC 29601

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