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319-321 Main St
Seneca, SC 29678
Office/Retail Property For Lease · 2,600 SF

Highlights

  • Located in the heart of downtown Seneca with direct frontage on Main Street.
  • Versatile layout suitable for retail, dining, bar, or office concepts.
  • Features street-to-street access and dedicated parking in addition to free municipal lot nearby.
  • Proximity to cultural and entertainment destinations, including Ram Cat Alley and the city’s Performing Arts Center.

Property Facts

Total Space Available 2,600 SF
Property Type Retail
Property Subtype Storefront
Gross Leasable Area 5,500 SF
Year Built/Renovated 1920/2011
Parking Ratio 2.31/1,000 SF

About the Property

321 Main Street in Seneca, South Carolina, is a commercial retail property with frontage on Main Street and rear access on West North First Street. It is located within the city’s commercial zoning area and includes parking on site with additional municipal parking across the street. The property is near Ram Cat Alley, the Seneca Performing Arts Center, and other downtown amenities.

  • Listing ID: 40544197

  • Date on Market: 5/15/2026

  • Last Updated:

  • Address: 319-321 Main St, Seneca, SC 29678

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