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Highlights

  • In close proximity to Laguna Freeway (SR-133), State Route 55 (SR-55), and the San Diego Freeway (I-405).
  • Renovations scheduled to start Summer 2025 and be completed Summer 2026
  • Located in a proven successful medical market with high growth, the site is minutes from John Wayne Airport.

All Available Spaces(6)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 1st Floor, Ste 106
  • 8,247-13,505 SF
  • Negotiable
  • $59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO
  • Medical
  • Full Build-Out
  • Now

Suite 106 (Contiguous up to 13,505 RSF) • Space Available: 8,247 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Close proximity to SR-133, SR-55, and I-405
  • 1st Floor, Ste 110
  • 5,258-13,505 SF
  • Negotiable
  • $59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO
  • Medical
  • Full Build-Out
  • Now

Suite 110 (Contiguous up to 13,505 RSF) • Space Available: 5,258 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Close proximity to SR-133, SR-55, and I-405
  • 1st Floor, Ste 112
  • 9,682 SF
  • Negotiable
  • $59.40 /SF/YR $4.95 /SF/MO $575,111 /YR $47,926 /MO
  • Medical
  • Full Build-Out
  • Now

Suite 112 • Space Available: 9,682 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Close proximity to SR-133, SR-55, and I-405
  • 1st Floor, Ste 116
  • 2,430 SF
  • Negotiable
  • $63.00 /SF/YR $5.25 /SF/MO $153,090 /YR $12,758 /MO
  • Office/Medical
  • Full Build-Out
  • Now

Suite 116 • Space Available: 2,430 SF • Lease Rate: $5.25/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Medical Space
  • Fits 7 - 20 People
  • 3rd Floor, Ste 308
  • 5,000-12,308 SF
  • Negotiable
  • $57.60 /SF/YR $4.80 /SF/MO $708,941 /YR $59,078 /MO
  • Office/Medical
  • Full Build-Out
  • Now

Suite 308 (Divisible to 5,000 RSF) • Space Available: 12,308 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Medical Space
  • Fits 13 - 99 People
  • 3rd Floor, Ste 315
  • 12,517 SF
  • Negotiable
  • $57.60 /SF/YR $4.80 /SF/MO $720,979 /YR $60,082 /MO
  • Office/Medical
  • Full Build-Out
  • Now

Suite 315 • Space Available: 12,517 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Medical Space
  • Fits 32 - 101 People
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 106 8,247-13,505 SF Negotiable $59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO Medical Full Build-Out Now
1st Floor, Ste 110 5,258-13,505 SF Negotiable $59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO Medical Full Build-Out Now
1st Floor, Ste 112 9,682 SF Negotiable $59.40 /SF/YR $4.95 /SF/MO $575,111 /YR $47,926 /MO Medical Full Build-Out Now
1st Floor, Ste 116 2,430 SF Negotiable $63.00 /SF/YR $5.25 /SF/MO $153,090 /YR $12,758 /MO Office/Medical Full Build-Out Now
3rd Floor, Ste 308 5,000-12,308 SF Negotiable $57.60 /SF/YR $4.80 /SF/MO $708,941 /YR $59,078 /MO Office/Medical Full Build-Out Now
3rd Floor, Ste 315 12,517 SF Negotiable $57.60 /SF/YR $4.80 /SF/MO $720,979 /YR $60,082 /MO Office/Medical Full Build-Out Now

1st Floor, Ste 106

Size
8,247-13,505 SF
Term
Negotiable
Rental Rate
$59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 110

Size
5,258-13,505 SF
Term
Negotiable
Rental Rate
$59.40 /SF/YR $4.95 /SF/MO $802,197 /YR $66,850 /MO
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 112

Size
9,682 SF
Term
Negotiable
Rental Rate
$59.40 /SF/YR $4.95 /SF/MO $575,111 /YR $47,926 /MO
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 116

Size
2,430 SF
Term
Negotiable
Rental Rate
$63.00 /SF/YR $5.25 /SF/MO $153,090 /YR $12,758 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

3rd Floor, Ste 308

Size
5,000-12,308 SF
Term
Negotiable
Rental Rate
$57.60 /SF/YR $4.80 /SF/MO $708,941 /YR $59,078 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

3rd Floor, Ste 315

Size
12,517 SF
Term
Negotiable
Rental Rate
$57.60 /SF/YR $4.80 /SF/MO $720,979 /YR $60,082 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 106

Size 8,247-13,505 SF
Term Negotiable
Rental Rate $59.40 /SF/YR
Space Use Medical
Condition Full Build-Out
Available Now

Suite 106 (Contiguous up to 13,505 RSF) • Space Available: 8,247 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Close proximity to SR-133, SR-55, and I-405

1st Floor, Ste 110

Size 5,258-13,505 SF
Term Negotiable
Rental Rate $59.40 /SF/YR
Space Use Medical
Condition Full Build-Out
Available Now

Suite 110 (Contiguous up to 13,505 RSF) • Space Available: 5,258 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Close proximity to SR-133, SR-55, and I-405

1st Floor, Ste 112

Size 9,682 SF
Term Negotiable
Rental Rate $59.40 /SF/YR
Space Use Medical
Condition Full Build-Out
Available Now

Suite 112 • Space Available: 9,682 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 36,692 SF of adjacent space
  • Close proximity to SR-133, SR-55, and I-405

1st Floor, Ste 116

Size 2,430 SF
Term Negotiable
Rental Rate $63.00 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Suite 116 • Space Available: 2,430 SF • Lease Rate: $5.25/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 7 - 20 People

3rd Floor, Ste 308

Size 5,000-12,308 SF
Term Negotiable
Rental Rate $57.60 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Suite 308 (Divisible to 5,000 RSF) • Space Available: 12,308 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 13 - 99 People

3rd Floor, Ste 315

Size 12,517 SF
Term Negotiable
Rental Rate $57.60 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Suite 315 • Space Available: 12,517 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 32 - 101 People

Property Overview

Newport Irvine Medical Center 3300 Irvine Avenue, Newport Beach, CA 92660 Premier practices warrant premiere real estate. The Newport Irvine Medical Center is poised to emerge as one of Orange County’s leading medical office buildings. This state-of-the-art facility has been meticulously designed to meet the expectations of the area’s affluent consumer groups, offering a unique and superior experience for both patients and medical professionals. The building is being transformed to offer a rare opportunity to lease new Class A construction, including large medical office spaces, in the highly sought-after Newport Beach submarket. Newport Irvine Medical Center welcomes a range of users from solo providers and large group practices, to new ambulatory surgery and imaging centers. ------------------------ Property Features: DESIGN FEATURES • Grand entrance with new 3 story atrium • Floor to ceiling glass lines to allow a continuous flow of natural light throughout the building • Centralized stairwells creating a wellness focused environment and limiting reliance on elevators • High quality finishes with subtle accents for an elevated aesthetic PROMINENT LOCATION & ACCESSIBILITY Located in a proven successful medical market with high growth, the site offers excellent accessibility from 3 major thoroughfares: • Laguna Freeway (SR-133) • State Route 55 (SR-55) • San Diego Freeway (I-405) • Minutes from John Wayne Airport, ideal for destination medicine IDEAL MARKET & SITE LOCATION The location is able to conveniently serve a population of 1.3 million and growing (within a 15 minute drive time) due to the quality of the roads, major thoroughfares, accessibility of the site, and unparalleled quality of life. The service is expected to grow by 20,000 people per year. ------------------------ 6 Suites Available: ------------------------ Suite 106 (Contiguous up to 13,505 RSF) • Space Available: 8,247 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ Suite 110 (Contiguous up to 13,505 RSF) • Space Available: 5,258 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ Suite 112 • Space Available: 9,682 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ Suite 116 • Space Available: 2,430 SF • Lease Rate: $5.25/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ Suite 308 (Divisible to 5,000 RSF) • Space Available: 12,308 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ Suite 315 • Space Available: 12,517 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization. ------------------------ MORE DETAILS: https://medwestrealty.com/property/newport-irvine-medical-center/ DOWNLOAD BROCHURE: https://medwestrealty.com/wp-content/uploads/2024/08/MW_3300-Irvine_LB17_WL.pdf

  • Courtyard
  • Signage
  • Wheelchair Accessible
  • Central Heating
  • Monument Signage
  • Outdoor Seating
  • Air Conditioning

Property Facts

Building Type
Office
Year Built/Renovated
1980/1997
Building Height
3 Stories
Building Size
75,000 SF
Building Class
B
Typical Floor Size
25,000 SF
Parking
280 Surface Parking Spaces
Covered Parking
Moderately walkable
70/100
Exceptionally drivable
100/100
Limited public transit
30/100
Moderately bikeable
60/100
  • Listing ID: 32967073

  • Date on Market: 7/9/2025

  • Last Updated:

  • Address: 3300 Irvine Ave, Newport Beach, CA 92660

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