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National Medical Center - Building II 3455 National Dr 4,000 - 16,000 SF of Office/Medical Space Available in Plano, TX 75025



Highlights
- Perfect location at the 4 corners of Plano, Frisco, Allen and McKinney
- Building Signage available for 10,000 SF or more leased
All Available Space(1)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Condition
- Available
National Medical Center Phase 2 is underway. We have space available on the Second Floor with units available between 4,000-16,000 SF. Building Signage on 121 if 10,000 SF or more is taken. Call today for more details. Delivery will be summer of 2027. ASC on the first floor.
- Lease rate does not include utilities, property expenses or building services
- Easy Access to Hwy 121
- 121 Signage
- Close Proximity to Baylor Centennial
| Space | Size | Term | Rental Rate | Space Use | Condition | Available |
| 2nd Floor, Ste 200 | 4,000-16,000 SF | 10 Years | $36.00 /SF/YR $3.00 /SF/MO $576,000 /YR $48,000 /MO | Office/Medical | Shell Space | December 01, 2026 |
2nd Floor, Ste 200
| Size |
| 4,000-16,000 SF |
| Term |
| 10 Years |
| Rental Rate |
| $36.00 /SF/YR $3.00 /SF/MO $576,000 /YR $48,000 /MO |
| Space Use |
| Office/Medical |
| Condition |
| Shell Space |
| Available |
| December 01, 2026 |
2nd Floor, Ste 200
| Size | 4,000-16,000 SF |
| Term | 10 Years |
| Rental Rate | $36.00 /SF/YR |
| Space Use | Office/Medical |
| Condition | Shell Space |
| Available | December 01, 2026 |
National Medical Center Phase 2 is underway. We have space available on the Second Floor with units available between 4,000-16,000 SF. Building Signage on 121 if 10,000 SF or more is taken. Call today for more details. Delivery will be summer of 2027. ASC on the first floor.
- Lease rate does not include utilities, property expenses or building services
- 121 Signage
- Easy Access to Hwy 121
- Close Proximity to Baylor Centennial
Property Overview
National Medical Center Building 2 is a multi-tenant medical office conveniently located on SH 121, right between the four major cities in Collin County, making it easily accessible for patients. Current tenants include Dallas and Frisco Dermatology, Texas Spine Consultants, North Star Diagnostic Imaging, Pain Management, Great Life Counseling, Great Smiles Dentistry, an Endodontist, Cooks Children's, and THR Family Medicine, along with an on-site ASC. Ownership shares in the new surgery center are available on a first-come, first-served basis. Call today to be part of this great mix of professionals.
- 24 Hour Access
- Signage
- Wi-Fi
- Air Conditioning
Property Facts
Select Tenants
- Cook's Children's
- Northstar Imaging
- Texas Health Resources PCP
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National Medical Center - Building II | 3455 National Dr
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