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Waltham Research Park Waltham, MA 02451 10,000 - 53,488 SF of Flex Space Available

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PARK HIGHLIGHTS

  • Up to 60,000 sq. ft. available. Waltham Research Park going thru major upgrades

PARK FACTS

Total Space Available 53,488 SF
Max. Contiguous 40,000 SF
Park Type Office Park
Features Signage

ALL AVAILABLE SPACES(3)

Display Rental Rate as

Waltham Research Park
350 Second Ave
10,000 - 40,000 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/B
Building Size
40,000 SF
Lot Size
2.37 AC
Year Built
2025
Clear Height
24’
Drive In Bays
2
Dock Doors
1
Power Supply
Amps: 1,200 Volts: 480 Phase: 3
Zoning
C - R&D Facility
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor
  • 30,000 SF
  • 5-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now

This property is suited for users in Laboratory Sciences and other fields down to research and development.

  • Can be combined with additional space(s) for up to 40,000 SF of adjacent space
  • Central Air Conditioning
  • 2 Loading Docks
  • Laboratory
  • 2nd Floor
  • 10,000 SF
  • 5-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now

This property is suited for users in Laboratory Sciences and other fields down to research and development.

  • Can be combined with additional space(s) for up to 40,000 SF of adjacent space
  • Central Air Conditioning
  • 2 Loading Docks
  • Laboratory
Space Size Term Rental Rate Space Use Condition Available
1st Floor 30,000 SF 5-10 Years Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
2nd Floor 10,000 SF 5-10 Years Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
Waltham Research Park
350 Second Ave
10,000 - 40,000 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/B
Building Size
40,000 SF
Lot Size
2.37 AC
Year Built
2025
Clear Height
24’
Drive In Bays
2
Dock Doors
1
Power Supply
Amps: 1,200 Volts: 480 Phase: 3
Zoning
C - R&D Facility

350 Second Ave - 1st Floor

Size
30,000 SF
Term
5-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Full Build-Out
Available
Now

350 Second Ave - 2nd Floor

Size
10,000 SF
Term
5-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Full Build-Out
Available
Now
Waltham Research Park
358 Second Ave
13,488 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type
Flex
Building Size
68,356 SF
Lot Size
3.96 AC
Year Built
1978
Clear Height
18’
Column Spacing
30’ x 40’
Drive In Bays
1
Dock Doors
3
Power Supply
Amps: 800 Volts: 480
Zoning
C - R&D Facility
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor
  • 13,488 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now

Waltham Research Park at 358 Second Ave in Waltham, MA offers 13,488 square feet of flexible office and lofted manufacturing space with 21-foot ceilings. The area includes an existing mezzanine, loading dock, server room, and accessible facilities such as showers and restrooms. The space is fully sprinkled and equipped with 600 amps, 480 volts, three-phase power, making it suitable for a variety of business needs.

  • 1 Loading Dock
  • Ability to build out office and manufacturing spac
  • Existing mezzanine
  • High Ceilings - 21 feet
  • Fully sprinklered
Space Size Term Rental Rate Space Use Condition Available
1st Floor 13,488 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
Waltham Research Park
358 Second Ave
13,488 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type
Flex
Building Size
68,356 SF
Lot Size
3.96 AC
Year Built
1978
Clear Height
18’
Column Spacing
30’ x 40’
Drive In Bays
1
Dock Doors
3
Power Supply
Amps: 800 Volts: 480
Zoning
C - R&D Facility

358 Second Ave - 1st Floor

Size
13,488 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Full Build-Out
Available
Now

350 Second Ave - 1st Floor

Size 30,000 SF
Term 5-10 Years
Rental Rate Upon Request
Space Use Flex
Condition Full Build-Out
Available Now

This property is suited for users in Laboratory Sciences and other fields down to research and development.

  • Can be combined with additional space(s) for up to 40,000 SF of adjacent space
  • 2 Loading Docks
  • Central Air Conditioning
  • Laboratory

350 Second Ave - 2nd Floor

Size 10,000 SF
Term 5-10 Years
Rental Rate Upon Request
Space Use Flex
Condition Full Build-Out
Available Now

This property is suited for users in Laboratory Sciences and other fields down to research and development.

  • Can be combined with additional space(s) for up to 40,000 SF of adjacent space
  • 2 Loading Docks
  • Central Air Conditioning
  • Laboratory

358 Second Ave - 1st Floor

Size 13,488 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Condition Full Build-Out
Available Now

Waltham Research Park at 358 Second Ave in Waltham, MA offers 13,488 square feet of flexible office and lofted manufacturing space with 21-foot ceilings. The area includes an existing mezzanine, loading dock, server room, and accessible facilities such as showers and restrooms. The space is fully sprinkled and equipped with 600 amps, 480 volts, three-phase power, making it suitable for a variety of business needs.

  • 1 Loading Dock
  • High Ceilings - 21 feet
  • Ability to build out office and manufacturing spac
  • Fully sprinklered
  • Existing mezzanine

PARK OVERVIEW

Waltham Research Park is a three building 210,000 square foot Office/Lab/and light manufacturing Park. Located in the heart of Waltham’s research cluster, Waltham Research Park’s Corporate neighbors include Sanofi-Genzyme, Thermo- Fisher Scientific, Massachusetts General Hospital and many more. The Park’s existing tenants are QinetiQ Inc, BioModels, Boston Dynamics and Snapdragon Chemistry. 350 Second Avenue, one of three buildings in the Park, is undergoing major renovations. Consisting of approximately 40,013 sq ft, 350 Second Ave is suited for users in Laboratory Sciences and other fields down to research and development. Building to be brought up to current life safety standards, including a new elevator to service the building’s two story section.

  • Signage
  • Listing ID: 25253458

  • Date on Market: 9/8/2025

  • Last Updated:

  • Address: 350 Second Ave, Waltham, MA 02451

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