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Park Highlights

  • Operable windows allowing fresh air through the offices
  • 24/7 key fob access
  • Abundant parking shared by six buildings within the office park
  • Hilltop location provides panoramic views from many of the suites
  • Natural light in common areas due to internal atrium
  • Well located near I-15 on and off ramps, as well as numerous retail establishments & commercial services

Park Facts

Total Space Available 3,127 SF
Park Type Office Park
Features
Atrium
  • Tenant Controlled HVAC

All Available Spaces(3)

Display Rental Rate as

Ruffin Business Center
3655 Ruffin Rd
821 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
19,637 SF
Building Height
3 Stories
Typical Floor Size
6,833 SF
  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor, Ste 205
  • 821 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Open office area/ bull pen, 3 perimeter offices of varying sizes and a smaller room that could be used for storage/IT or very small office. Two of the offices are on the window line with operable windows. One being a corner office with window line along two walls. See floor plan.

  • Listed rate may not include certain utilities, building services and property expenses
  • Office intensive layout
  • Space is in Excellent Condition
  • Operable windows allowing fresh third floor breeze
  • Fully Built-Out as Standard Office
  • Fits 3 - 8 People
  • Entry to suite near elevator & restrooms
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor, Ste 205 821 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
Ruffin Business Center
3655 Ruffin Rd
821 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
19,637 SF
Building Height
3 Stories
Typical Floor Size
6,833 SF

3655 Ruffin Rd - 2nd Floor - Ste 205

Size
821 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
Now
Ruffin Business Center
3645 Ruffin Rd
967 - 2,306 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
21,168 SF
Building Height
3 Stories
Typical Floor Size
7,056 SF
  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 3rd Floor, Ste 315
  • 1,339 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Call to show.

  • Fully Built-Out as Standard Medical Space
  • Fits 4 - 11 People
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • 3rd Floor, Ste 360
  • 967 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Call to show.

  • Fully Built-Out as Standard Medical Space
  • Fits 3 - 8 People
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
Space Size Term Rental Rate Space Use Build-Out Available
3rd Floor, Ste 315 1,339 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 360 967 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
Ruffin Business Center
3645 Ruffin Rd
967 - 2,306 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
21,168 SF
Building Height
3 Stories
Typical Floor Size
7,056 SF

3645 Ruffin Rd - 3rd Floor - Ste 315

Size
1,339 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3645 Ruffin Rd - 3rd Floor - Ste 360

Size
967 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3655 Ruffin Rd - 2nd Floor - Ste 205

Size 821 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available Now

Open office area/ bull pen, 3 perimeter offices of varying sizes and a smaller room that could be used for storage/IT or very small office. Two of the offices are on the window line with operable windows. One being a corner office with window line along two walls. See floor plan.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Office intensive layout
  • Fits 3 - 8 People
  • Space is in Excellent Condition
  • Entry to suite near elevator & restrooms
  • Operable windows allowing fresh third floor breeze

3645 Ruffin Rd - 3rd Floor - Ste 315

Size 1,339 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Call to show.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 4 - 11 People
  • Space is in Excellent Condition

3645 Ruffin Rd - 3rd Floor - Ste 360

Size 967 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Call to show.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 3 - 8 People
  • Space is in Excellent Condition

Park Overview

Ruffin Business Center provides new tenants with a wide range of spaces in two separate buildings. Each building is approximately 20,000 SF, both featuring an interior atrium area allowing for abundant natural light in the core common areas and core areas of some suites.. These buildings are situated at a prominent intersection with excellent access to major thoroughfares in the heart of Kearny Mesa, San Diego. Surrounded by shops, restaurants and retailers, Ruffin Business Center is the perfect choice of location for any business.

  • Atrium
  • Tenant Controlled HVAC
Moderately walkable
70/100
Exceptionally drivable
100/100
Limited public transit
30/100
Fairly bikeable
50/100
  • Listing ID: 40853212

  • Date on Market: 6/9/2026

  • Last Updated:

  • Address: 3665 Ruffin Rd, San Diego, CA 92123

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