Your email has been sent.
Palmdale Regional Medical Center 38660 Medical Center Dr 2,130 - 21,125 SF of Medical Space Available in Palmdale, CA 93551



Highlights
- Three-story medical office building on hospital campus.
- ±59,577 SF total building square footage.
- Generous tenant improvement allowance for customization.
- Direct enclosed walkway access to Palmdale Regional Medical Center.
- Fully built-out suites available for immediate occupancy.
- Ample parking with two patient entries.
All Available Spaces(6)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Build-Out
- Available
Prime first-floor location with lobby entry and divisible layout. Shell space ready for build-to-suit customization.
- Lease rate does not include utilities, property expenses or building services
- Lobby entry location
- Build-to-suit flexibility
- Space is in Excellent Condition
- Divisible to ±3,000 SF
Second-floor shell space designed for build-to-suit with architect-ready plans. Ideal for specialized medical use.
- Lease rate does not include utilities, property expenses or building services
- Plug & Play
- Build-to-suit option
- Space is in Excellent Condition
- Architect-ready space plan
- Efficient second-floor layout
Second-floor shell space offering build-to-suit opportunities with architect-ready plans for tailored medical configurations.
- Lease rate does not include utilities, property expenses or building services
- Plug & Play
- Architect-ready plans
- Space is in Excellent Condition
- Flexible design options
- Build-to-suit capability
Third-floor shell space with build-to-suit potential and architect-ready plans for custom medical layouts.
- Lease rate does not include utilities, property expenses or building services
- Plug & Play
- Architect-ready design
- Space is in Excellent Condition
- Customizable shell space
- Build-to-suit flexibility
Fully built-out third-floor suite featuring eight exam rooms, two private offices, reception, breakroom, and restroom. Available December 2026.
- Lease rate does not include utilities, property expenses or building services
- Reception Area
- Private Restrooms
- Two private offices
- Fully Built-Out as Standard Medical Space
- 8 Private Offices
- Eight exam rooms
- Reception and breakroom included
Second-generation, fully built-out space with functional layout for medical practice operations.
- Lease rate does not include utilities, property expenses or building services
- Office intensive layout
- Fully built-out design
- Ready for immediate use
- Fully Built-Out as Standard Medical Space
- Plug & Play
- Efficient medical layout
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
| 1st Floor, Ste A100 | 3,000-6,747 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Shell Space | Now |
| 2nd Floor, Ste A220 | 2,130 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Shell Space | Now |
| 2nd Floor, Ste A290 | 3,090 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Shell Space | Now |
| 3rd Floor, Ste A340 | 3,984 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Shell Space | Now |
| 3rd Floor, Ste A350 | 2,699 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Full Build-Out | December 01, 2026 |
| 3rd Floor, Ste A380 | 2,475 SF | 1-5 Years | Upon Request Upon Request Upon Request Upon Request | Medical | Full Build-Out | 30 Days |
1st Floor, Ste A100
| Size |
| 3,000-6,747 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Shell Space |
| Available |
| Now |
2nd Floor, Ste A220
| Size |
| 2,130 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Shell Space |
| Available |
| Now |
2nd Floor, Ste A290
| Size |
| 3,090 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Shell Space |
| Available |
| Now |
3rd Floor, Ste A340
| Size |
| 3,984 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Shell Space |
| Available |
| Now |
3rd Floor, Ste A350
| Size |
| 2,699 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Full Build-Out |
| Available |
| December 01, 2026 |
3rd Floor, Ste A380
| Size |
| 2,475 SF |
| Term |
| 1-5 Years |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Medical |
| Build-Out |
| Full Build-Out |
| Available |
| 30 Days |
1st Floor, Ste A100
| Size | 3,000-6,747 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Shell Space |
| Available | Now |
Prime first-floor location with lobby entry and divisible layout. Shell space ready for build-to-suit customization.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Lobby entry location
- Divisible to ±3,000 SF
- Build-to-suit flexibility
2nd Floor, Ste A220
| Size | 2,130 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Shell Space |
| Available | Now |
Second-floor shell space designed for build-to-suit with architect-ready plans. Ideal for specialized medical use.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Plug & Play
- Architect-ready space plan
- Build-to-suit option
- Efficient second-floor layout
2nd Floor, Ste A290
| Size | 3,090 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Shell Space |
| Available | Now |
Second-floor shell space offering build-to-suit opportunities with architect-ready plans for tailored medical configurations.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Plug & Play
- Flexible design options
- Architect-ready plans
- Build-to-suit capability
3rd Floor, Ste A340
| Size | 3,984 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Shell Space |
| Available | Now |
Third-floor shell space with build-to-suit potential and architect-ready plans for custom medical layouts.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Plug & Play
- Customizable shell space
- Architect-ready design
- Build-to-suit flexibility
3rd Floor, Ste A350
| Size | 2,699 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Full Build-Out |
| Available | December 01, 2026 |
Fully built-out third-floor suite featuring eight exam rooms, two private offices, reception, breakroom, and restroom. Available December 2026.
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Medical Space
- Reception Area
- 8 Private Offices
- Private Restrooms
- Eight exam rooms
- Two private offices
- Reception and breakroom included
3rd Floor, Ste A380
| Size | 2,475 SF |
| Term | 1-5 Years |
| Rental Rate | Upon Request |
| Space Use | Medical |
| Build-Out | Full Build-Out |
| Available | 30 Days |
Second-generation, fully built-out space with functional layout for medical practice operations.
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Medical Space
- Office intensive layout
- Plug & Play
- Fully built-out design
- Efficient medical layout
- Ready for immediate use
Property Overview
Palmdale Medical Plaza is a three-story medical office building located on the campus of Palmdale Regional Medical Center in Palmdale, California. Spanning approximately 59,577 square feet, the property offers direct connectivity to the hospital through an enclosed walkway, ensuring seamless access for healthcare providers and patients. The building features a mix of fully built-out suites and shell spaces, providing flexibility for a variety of medical practices. Tenants benefit from a generous improvement allowance, ample parking, and proximity to the newly opened OB and Maternity Unit at the adjacent hospital. With two patient entries and convenient access to major roadways, this location is designed to support efficient operations and patient care. Positioned within a thriving medical campus, Palmdale Medical Plaza delivers a professional environment tailored to healthcare providers seeking a well-connected and functional space in the Antelope Valley region.
Property Facts
Presented by
Palmdale Regional Medical Center | 38660 Medical Center Dr
Hmm, there seems to have been an error sending your message. Please try again.
Thanks! Your message was sent.






