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Highlights

  • Within proximity to North Star Mall, San Antonio International Airport, and premier shopping and dining destinations.
  • Secure parking within a covered parking garage.
  • On-site conference room is available for tenant use.
  • Advanced security and controlled keycard access.

All Available Spaces(6)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor, Ste Suite 225
  • 2,358 SF
  • Negotiable
  • $25.00 /SF/YR $2.08 /SF/MO $58,950 /YR $4,913 /MO
  • Office/Medical
  • -
  • Now
  • Rate includes utilities, building services and property expenses
  • 2nd Floor, Ste Suite 233
  • 2,177 SF
  • Negotiable
  • $25.00 /SF/YR $2.08 /SF/MO $54,425 /YR $4,535 /MO
  • Office
  • -
  • Now
  • Rate includes utilities, building services and property expenses
  • 4th Floor, Ste Suite 445
  • 2,689 SF
  • Negotiable
  • $25.00 /SF/YR $2.08 /SF/MO $67,225 /YR $5,602 /MO
  • Office/Medical
  • -
  • Now
  • Rate includes utilities, building services and property expenses
  • 5th Floor, Ste Suite 525
  • 4,074 SF
  • Negotiable
  • $25.00 /SF/YR $2.08 /SF/MO $101,850 /YR $8,488 /MO
  • Office/Medical
  • -
  • 30 Days
  • Rate includes utilities, building services and property expenses
  • 5th Floor, Ste Suite 560
  • 2,452 SF
  • Negotiable
  • $25.00 /SF/YR $2.08 /SF/MO $61,300 /YR $5,108 /MO
  • Office/Medical
  • -
  • Now
  • Rate includes utilities, building services and property expenses
  • 6th Floor, Ste Suite 600
  • 4,525 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor, Ste Suite 225 2,358 SF Negotiable $25.00 /SF/YR $2.08 /SF/MO $58,950 /YR $4,913 /MO Office/Medical - Now
2nd Floor, Ste Suite 233 2,177 SF Negotiable $25.00 /SF/YR $2.08 /SF/MO $54,425 /YR $4,535 /MO Office - Now
4th Floor, Ste Suite 445 2,689 SF Negotiable $25.00 /SF/YR $2.08 /SF/MO $67,225 /YR $5,602 /MO Office/Medical - Now
5th Floor, Ste Suite 525 4,074 SF Negotiable $25.00 /SF/YR $2.08 /SF/MO $101,850 /YR $8,488 /MO Office/Medical - 30 Days
5th Floor, Ste Suite 560 2,452 SF Negotiable $25.00 /SF/YR $2.08 /SF/MO $61,300 /YR $5,108 /MO Office/Medical - Now
6th Floor, Ste Suite 600 4,525 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office - Now

2nd Floor, Ste Suite 225

Size
2,358 SF
Term
Negotiable
Rental Rate
$25.00 /SF/YR $2.08 /SF/MO $58,950 /YR $4,913 /MO
Space Use
Office/Medical
Build-Out
-
Available
Now

2nd Floor, Ste Suite 233

Size
2,177 SF
Term
Negotiable
Rental Rate
$25.00 /SF/YR $2.08 /SF/MO $54,425 /YR $4,535 /MO
Space Use
Office
Build-Out
-
Available
Now

4th Floor, Ste Suite 445

Size
2,689 SF
Term
Negotiable
Rental Rate
$25.00 /SF/YR $2.08 /SF/MO $67,225 /YR $5,602 /MO
Space Use
Office/Medical
Build-Out
-
Available
Now

5th Floor, Ste Suite 525

Size
4,074 SF
Term
Negotiable
Rental Rate
$25.00 /SF/YR $2.08 /SF/MO $101,850 /YR $8,488 /MO
Space Use
Office/Medical
Build-Out
-
Available
30 Days

5th Floor, Ste Suite 560

Size
2,452 SF
Term
Negotiable
Rental Rate
$25.00 /SF/YR $2.08 /SF/MO $61,300 /YR $5,108 /MO
Space Use
Office/Medical
Build-Out
-
Available
Now

6th Floor, Ste Suite 600

Size
4,525 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

2nd Floor, Ste Suite 225

Size 2,358 SF
Term Negotiable
Rental Rate $25.00 /SF/YR
Space Use Office/Medical
Build-Out -
Available Now

  • Rate includes utilities, building services and property expenses

2nd Floor, Ste Suite 233

Size 2,177 SF
Term Negotiable
Rental Rate $25.00 /SF/YR
Space Use Office
Build-Out -
Available Now

  • Rate includes utilities, building services and property expenses

4th Floor, Ste Suite 445

Size 2,689 SF
Term Negotiable
Rental Rate $25.00 /SF/YR
Space Use Office/Medical
Build-Out -
Available Now

  • Rate includes utilities, building services and property expenses

5th Floor, Ste Suite 525

Size 4,074 SF
Term Negotiable
Rental Rate $25.00 /SF/YR
Space Use Office/Medical
Build-Out -
Available 30 Days

  • Rate includes utilities, building services and property expenses

5th Floor, Ste Suite 560

Size 2,452 SF
Term Negotiable
Rental Rate $25.00 /SF/YR
Space Use Office/Medical
Build-Out -
Available Now

  • Rate includes utilities, building services and property expenses

Property Overview

The Mercantile Building, located at 40 NE Loop 410 in San Antonio, Texas, is a distinguished Class A office property encompassing 248,640 square feet. Its strategic positioning along I-410 near the US-281 intersection ensures exceptional accessibility, while its proximity to North Star Mall, San Antonio International Airport, and premier shopping and dining destinations enhances its appeal to discerning tenants. Comprehensive Amenities: • Elegant Lobby and Common Areas: The building welcomes occupants with a beautifully designed lobby featuring unique artwork and biophilic elements, creating a stimulating atmosphere. • Conference Facilities: An on-site conference room is available for tenant use, enhancing business optics and operations. • Secure Parking: An attached covered parking garage provides convenient and protected parking options. • On-Site Deli: A deli within the building offers accessible dining choices for tenants. • Advanced Security: Controlled card key access available 24/7, complemented by on-site security personnel, ensures a safe working environment. • Professional Management: On-site facilities and property management teams deliver prompt and efficient services. • Open Atrium Spaces: The open atrium common areas serve as tranquil spaces for relaxation and informal meetings.

  • 24 Hour Access
  • Atrium
  • Banking
  • Bus Line
  • Controlled Access
  • Courtyard
  • Property Manager on Site
  • Restaurant
  • Signage

Property Facts

Building Type
Office
Year Built
1981
Building Height
7 Stories
Building Size
217,838 SF
Building Class
A
Typical Floor Size
31,120 SF
Unfinished Ceiling Height
15’
Parking
280 Surface Parking Spaces
840 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 4th
  • Aflac
  • Finance and Insurance
  • 3rd
  • Altus Hospice
  • Health Care and Social Assistance
  • 6th
  • Assessment Technologies
  • Professional, Scientific, and Technical Services
  • 2nd
  • Cherokee Nation Businesses
  • Professional, Scientific, and Technical Services
  • 4th
  • Kearney, McWilliams & Davis Attorneys At Law
  • Professional, Scientific, and Technical Services
  • 3rd
  • King & Sommer LLP
  • Professional, Scientific, and Technical Services
  • 5th
  • LaHood Norton Law Group, PLLC
  • Professional, Scientific, and Technical Services
  • 4th
  • SeeKing HR
  • Professional, Scientific, and Technical Services
  • 5th
  • Strayer University
  • Educational Services
  • 6th
  • Texas A&M University Regional Prospective Student
  • Educational Services
Fairly walkable
50/100
Exceptionally drivable
100/100
Some public transit
50/100
Somewhat bikeable
30/100
  • Listing ID: 34645460

  • Date on Market: 3/25/2026

  • Last Updated:

  • Address: 40 NE Loop 410, San Antonio, TX 78216

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