401 16th St N
Saint Petersburg, FL 33705
Build to Suit Medical Office Plaza · Medical Property For Lease · 4,677 SF

Located just blocks from downtown Saint Petersburg and adjacent to Saint Anthony’s Hospital, 400 15th St N presents a fully renovated medical office property in one of the city’s most active healthcare corridors. The building has undergone a comprehensive renovation from top to bottom, including upgraded electrical systems, new cabinetry and counters, and modern HVAC improvements. These enhancements create a professional and comfortable environment tailored for clinical operations. The interior layout is designed for medical use, featuring a series of private offices, exam rooms, and break areas that support a variety of healthcare functions. The property’s CCS-2 zoning allows for a broad mix of commercial and medical uses, offering flexibility for future ownership or occupancy strategies. Two adjacent vacant lots provide significant value-add potential. One lot has been graveled for immediate parking use, while the second offers the opportunity for fencing or specialized outdoor space—ideal for veterinary or wellness practices. The location benefits from strong visibility and accessibility, with proximity to major thoroughfares, public transit, and walkable downtown amenities. With its strategic location, modernized infrastructure, and adaptable layout, 400 15th St N is well-positioned for long-term value in Saint Petersburg’s growing medical and professional services market. ?? Medical Office Building for Lease – Prime St. Petersburg Location! ?? 400 N 15th Street, St. Petersburg, FL ±4,677 SQ FT | Move-In Ready | High-Visibility Corner Discover an exceptional opportunity to lease a modern, professional medical office building in the heart of St. Petersburg. Perfect for medical practices, specialty clinics, or healthcare service providers seeking a highly accessible and well-designed space. Property Highlights ±4,677 sq ft of adaptable medical office space Prominent freestanding building with excellent curb appeal Ideal layout for multi-provider practices or specialized medical services Multiple exam rooms, private offices, reception area, and procedure space Ample on-site parking for staff and patients High-visibility location near major roadways and St. Pete medical hubs Move-in ready or customizable to fit your practice’s needs