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Isom Road Business Park San Antonio, TX 78216 498 - 6,548 SF of Space Available

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Park Highlights

Outstanding North Central Location
Attractive Business Park Setting
Exterior Signage & Visibility

Immediate Access to US 281, San Pedro Ave & Loop 410
Grade-Level Doors
Ample Parking

Park Facts

Total Space Available	6,548 SF	Park Type	Office Park

Total Space Available	6,548 SF
Park Type	Office Park

Display Rental Rate as

Isom Road Business Park

401 Isom Rd

1,731 - 2,291 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,020 - $2,673 /MO $24,234 - $32,074 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

18,932 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Zoning

C-3 - General Commercial District

Space
Size
Term
Rental Rate
Space Use
Condition
Available

1st Floor - 410
2,291 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO
Flex
-
Now

401 Isom Rd, San Antonio, TX for lease Interior Photo- Image 1 of 1 — Interior Photo

Lease rate does not include utilities, property expenses or building services
Two (2) Grade-Level Doors
Approx. 80% Office and 20% Warehouse

Space is in Excellent Condition
Two (2) Restrooms

Isom Road Business Park Leasing Brochure

1st Floor - 445
1,731 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO
Flex
-
Now

401 Isom Rd, San Antonio, TX for lease Floor Plan- Image 1 of 1 — Floor Plan

Lease rate does not include utilities, property expenses or building services
One (1) Grade Level Door

Space is in Excellent Condition

Isom Road Business Park Leasing Brochure

Space	Size	Term	Rental Rate	Space Use	Condition	Available
1st Floor - 410	2,291 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO	Flex	-	Now
1st Floor - 445	1,731 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO	Flex	-	Now

Isom Road Business Park

401 Isom Rd

1,731 - 2,291 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,020 - $2,673 /MO $24,234 - $32,074 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

18,932 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Zoning

C-3 - General Commercial District

Size

2,291 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO

Space Use

Flex

Condition

Available

Now

Size

1,731 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO

Space Use

Flex

Condition

Available

Now

Isom Road Business Park

401 Isom Rd

2,028 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,366 /MO $28,392 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

26,458 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Dock Doors

Zoning

C-3 - General Commercial District

Space
Size
Term
Rental Rate
Space Use
Condition
Available

1st Floor - 540
2,028 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO
Flex
-
60 Days

Lease rate does not include utilities, property expenses or building services

Isom Road Business Park Leasing Brochure

Space	Size	Term	Rental Rate	Space Use	Condition	Available
1st Floor - 540	2,028 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO	Flex	-	60 Days

Isom Road Business Park

401 Isom Rd

2,028 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,366 /MO $28,392 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

26,458 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Dock Doors

Zoning

C-3 - General Commercial District

Size

2,028 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO

Space Use

Flex

Condition

Available

60 Days

Spaces are matched based on search filters: space use, price, and size

Isom Road Business Park

401 Isom Rd - Building 200

498 SF | $16.00 /SF/YR $1.33 /SF/MO $172.22 /m²/YR $14.35 /m²/MO $664.00 /MO $7,968 /YR | View Building Details

Building Type/Class

Office/B

Year Built

1976

Building Size

11,727 SF

Building Height

1 Story

Typical Floor Size

11,727 SF

Parking

25 Spaces

Space
Size
Term
Rental Rate
Space Use
Condition
Available

1st Floor, Ste 230
498 SF
Negotiable
$16.00 /SF/YR $1.33 /SF/MO $7,968 /YR $664.00 /MO
Office
-
Now

Lease rate does not include utilities, property expenses or building services
Space is in Excellent Condition

Fits 2 - 4 People

Isom Road Business Park Leasing Brochure

Space	Size	Term	Rental Rate	Space Use	Condition	Available
1st Floor, Ste 230	498 SF	Negotiable	$16.00 /SF/YR $1.33 /SF/MO $7,968 /YR $664.00 /MO	Office	-	Now

Isom Road Business Park

401 Isom Rd - Building 200

498 SF | $16.00 /SF/YR $1.33 /SF/MO $172.22 /m²/YR $14.35 /m²/MO $664.00 /MO $7,968 /YR | View Building Details

Building Type/Class

Office/B

Year Built

1976

Building Size

11,727 SF

Building Height

1 Story

Typical Floor Size

11,727 SF

Parking

25 Spaces

Size

498 SF

Term

Negotiable

Rental Rate

$16.00 /SF/YR $1.33 /SF/MO $7,968 /YR $664.00 /MO

Space Use

Office

Condition

Available

Now

Isom Road Business Park

401 Isom Rd - Building 400

1,731 - 4,022 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,020 - $4,692 /MO $24,234 - $56,308 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

18,932 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Zoning

C-3 - General Commercial District

Space
Size
Term
Rental Rate
Space Use
Condition
Available

1st Floor - 410
2,291 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO
Flex
-
Now

Lease rate does not include utilities, property expenses or building services
Two (2) Grade-Level Doors
Approx. 80% Office and 20% Warehouse

Space is in Excellent Condition
Two (2) Restrooms

Isom Road Business Park Leasing Brochure

1st Floor - 445
1,731 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO
Flex
-
Now

Lease rate does not include utilities, property expenses or building services
One (1) Grade Level Door

Space is in Excellent Condition

Isom Road Business Park Leasing Brochure

Space	Size	Term	Rental Rate	Space Use	Condition	Available
1st Floor - 410	2,291 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO	Flex	-	Now
1st Floor - 445	1,731 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO	Flex	-	Now

Isom Road Business Park

401 Isom Rd - Building 400

1,731 - 4,022 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,020 - $4,692 /MO $24,234 - $56,308 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

18,932 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Zoning

C-3 - General Commercial District

Size

2,291 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $32,074 /YR $2,673 /MO

Space Use

Flex

Condition

Available

Now

Size

1,731 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $24,234 /YR $2,020 /MO

Space Use

Flex

Condition

Available

Now

Isom Road Business Park

401 Isom Rd - Building 500

2,028 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,366 /MO $28,392 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

26,458 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Dock Doors

Zoning

C-3 - General Commercial District

Space
Size
Term
Rental Rate
Space Use
Condition
Available

1st Floor - 540
2,028 SF
Negotiable
$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO
Flex
-
60 Days

Lease rate does not include utilities, property expenses or building services

Isom Road Business Park Leasing Brochure

Space	Size	Term	Rental Rate	Space Use	Condition	Available
1st Floor - 540	2,028 SF	Negotiable	$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO	Flex	-	60 Days

Isom Road Business Park

401 Isom Rd - Building 500

2,028 SF | $14.00 /SF/YR $1.17 /SF/MO $150.69 /m²/YR $12.56 /m²/MO $2,366 /MO $28,392 /YR | View Building Details

Building Type/Class

Flex/B

Building Size

26,458 SF

Lot Size

5.25 AC

Year Built

1976

Drive In Bays

Dock Doors

Zoning

C-3 - General Commercial District

Size

2,028 SF

Term

Negotiable

Rental Rate

$14.00 /SF/YR $1.17 /SF/MO $28,392 /YR $2,366 /MO

Space Use

Flex

Condition

Available

60 Days

1 of 1

Videos

Matterport 3D Exterior

Matterport 3D Tour

Photos

Street View Street

Map

Size	498 SF
Term	Negotiable
Rental Rate	$16.00 /SF/YR
Space Use	Office
Condition	-
Available	Now

Lease rate does not include utilities, property expenses or building services
Fits 2 - 4 People
Space is in Excellent Condition

Isom Road Business Park Leasing Brochure

1 of 1

Videos

Matterport 3D Exterior

Matterport 3D Tour

Photos

Street View Street

Map

Size	2,291 SF
Term	Negotiable
Rental Rate	$14.00 /SF/YR
Space Use	Flex
Condition	-
Available	Now

Lease rate does not include utilities, property expenses or building services
Space is in Excellent Condition
Two (2) Grade-Level Doors
Two (2) Restrooms
Approx. 80% Office and 20% Warehouse

Isom Road Business Park Leasing Brochure

1 of 1

Videos

Matterport 3D Exterior

Matterport 3D Tour

Photos

Street View Street

Map

Size	1,731 SF
Term	Negotiable
Rental Rate	$14.00 /SF/YR
Space Use	Flex
Condition	-
Available	Now

Lease rate does not include utilities, property expenses or building services
Space is in Excellent Condition
One (1) Grade Level Door

Isom Road Business Park Leasing Brochure

1 of 1

Videos

Matterport 3D Exterior

Matterport 3D Tour

Photos

Street View Street

Map

Size	2,028 SF
Term	Negotiable
Rental Rate	$14.00 /SF/YR
Space Use	Flex
Condition	-
Available	60 Days

Lease rate does not include utilities, property expenses or building services

Isom Road Business Park Leasing Brochure

Site Plan

Park Overview

Now available at Isom Road Business Park, this versatile flex/service center offers ±498 to ±2,291 SF in a highly sought-after North Central San Antonio location. The property features immediate access to US 281, San Pedro Avenue, and Loop 410, making it an ideal solution for businesses seeking convenience, connectivity, and visibility. Set within an attractive business park environment, the space includes grade-level doors, exterior signage opportunities, and ample on-site parking. Designed to support a range of uses, this well-located property delivers functionality, accessibility, and a professional setting for growing and established businesses alike. Contact us today to schedule a tour.

Isom Road Business Park Leasing Brochure