Former Jefferson County Health Center 405 Main St 9,800 SF Vacant Office Building Hillsboro, MO 63050 $795,000 ($81.12/SF)

Positioned directly across from the Jefferson County Courthouse in downtown Hillsboro, 405 Main Street presents a substantial office and adaptive reuse opportunity totaling nearly 10,000 square feet. Formerly occupied as the Jefferson County Health Center, the property offers extensive finished space suitable for a broad range of commercial, institutional, medical, educational, and community-oriented uses.
The building has been well maintained and is reported to be in above-average condition, with operational building systems and a layout capable of supporting immediate occupancy or repositioning. Its courthouse-adjacent location provides strong visibility, convenient access, and proximity to government offices and downtown services.
With its size, established infrastructure, and flexible floor plan, the property offers an attractive opportunity for owner-users, investors, medical providers, educational organizations, community service groups, or businesses seeking a prominent Hillsboro location.