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Loomis Crossing 4300 W Layton Ave 2,000 - 21,953 SF of 4-Star Office/Medical Space Available in Greenfield, WI 53221

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HIGHLIGHTS

  • Build-to-suit medical/medical office space
  • Divisible to 2,000 sf
  • 10 minutes from downtown Milwaukee and 8 minutes from General Mitchell International Airport
  • Signage opportunities available
  • Conveniently located, just off I-43/894 with freeway visibility

ALL AVAILABLE SPACES(2)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor
  • 2,000-5,802 SF
  • Negotiable
  • $24.00 /SF/YR $2.00 /SF/MO $139,248 /YR $11,604 /MO
  • Office/Medical
  • Partial Build-Out
  • 120 Days

*Tenant Incentive: 6 Months Free Base Rent For New Leases Signed Prior to 4/30/2026*

  • Lease rate does not include utilities, property expenses or building services
  • Build-to-suit medical or office space
  • Can be combined with additional space(s) for up to 21,953 SF of adjacent space
  • Ample on-site parking
  • 2nd Floor
  • 2,000-16,151 SF
  • Negotiable
  • $24.00 /SF/YR $2.00 /SF/MO $387,624 /YR $32,302 /MO
  • Office/Medical
  • Partial Build-Out
  • 120 Days

*Tenant Incentive: 6 Months Free Base Rent For New Leases Signed Prior to 4/30/2026*

  • Lease rate does not include utilities, property expenses or building services
  • Build-to-suit medical or office space
  • Can be combined with additional space(s) for up to 21,953 SF of adjacent space
  • Ample on-site parking
Space Size Term Rental Rate Space Use Condition Available
1st Floor 2,000-5,802 SF Negotiable $24.00 /SF/YR $2.00 /SF/MO $139,248 /YR $11,604 /MO Office/Medical Partial Build-Out 120 Days
2nd Floor 2,000-16,151 SF Negotiable $24.00 /SF/YR $2.00 /SF/MO $387,624 /YR $32,302 /MO Office/Medical Partial Build-Out 120 Days

1st Floor

Size
2,000-5,802 SF
Term
Negotiable
Rental Rate
$24.00 /SF/YR $2.00 /SF/MO $139,248 /YR $11,604 /MO
Space Use
Office/Medical
Condition
Partial Build-Out
Available
120 Days

2nd Floor

Size
2,000-16,151 SF
Term
Negotiable
Rental Rate
$24.00 /SF/YR $2.00 /SF/MO $387,624 /YR $32,302 /MO
Space Use
Office/Medical
Condition
Partial Build-Out
Available
120 Days

1st Floor

Size 2,000-5,802 SF
Term Negotiable
Rental Rate $24.00 /SF/YR
Space Use Office/Medical
Condition Partial Build-Out
Available 120 Days

*Tenant Incentive: 6 Months Free Base Rent For New Leases Signed Prior to 4/30/2026*

  • Lease rate does not include utilities, property expenses or building services
  • Can be combined with additional space(s) for up to 21,953 SF of adjacent space
  • Build-to-suit medical or office space
  • Ample on-site parking

2nd Floor

Size 2,000-16,151 SF
Term Negotiable
Rental Rate $24.00 /SF/YR
Space Use Office/Medical
Condition Partial Build-Out
Available 120 Days

*Tenant Incentive: 6 Months Free Base Rent For New Leases Signed Prior to 4/30/2026*

  • Lease rate does not include utilities, property expenses or building services
  • Can be combined with additional space(s) for up to 21,953 SF of adjacent space
  • Build-to-suit medical or office space
  • Ample on-site parking

PROPERTY OVERVIEW

The Loomis Crossing Medical Office Building is one of the first in the Milwaukee area built specifically to enhance health and wellness. This 40,000 SF Class A facility, delivered in early 2024, features high-performance materials, advanced mechanical systems, and modern design - all aimed at supporting a productive, comfortable, and efficient work environment for healthcare professionals and patients alike. Loomis Crossing is a dynamic, 35+ acre mixed-use development positioned as a premier live-work-play destination. Strategically located at the intersection of Layton Avenue and Loomis Road in Greenfield, the development spans both sides of I-894—offering exceptional visibility, easy freeway access, and high-profile signage opportunities. The south campus includes the medical office building and 267 luxury apartment units, while the north campus is home to The Turf Indoor/Outdoor Skatepark (opened Summer 2025) and nearly 20 acres of land available for future development units. The north campus includes The Turf Indoor/Outdoor Skatepark (opened Summer 2025) and nearly 20 acres for future development.

  • Signage
  • Air Conditioning

PROPERTY FACTS

Building Type
Office
Year Built
2024
LoopNet Rating
4 Star
Building Height
2 Stories
Building Size
40,288 SF
Building Class
A
Typical Floor Size
20,144 SF
  • Listing ID: 22009543

  • Date on Market: 1/19/2021

  • Last Updated:

  • Address: 4300 W Layton Ave, Greenfield, WI 53221

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