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4381 W Flamingo Rd
Las Vegas, NV 89103
26,000SF Spa & Wellness | Palms Place · Retail Property For Lease · 250,000 SF

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Property Facts

Total Space Available 24,500 SF
Property Type Hospitality
Property Subtype Hotel
Building Size 250,000 SF
Year Built 2008

About the Property

Flagship Spa & Longevity Opportunity | 26,000 SF | Palms Place Resort Las Vegas Rare opportunity to lease and operate a 26,000 square foot spa and wellness facility located inside Palms Place Resort, directly connected to Palms Casino Resort via the SkyTube air bridge. The space spans the sixth and seventh floors and offers a flexible configuration for a large-scale spa operator, longevity concept, medical wellness provider, or integrated wellness brand. Sixth Floor – Spa Level | ±14,000 SF The sixth floor includes a fully built spa environment featuring one of only two traditional hammams in Las Vegas, separate men's and women's wet spa areas, two quiet relaxation rooms, and eight private treatment rooms, each pre-plumbed with sinks and cabinetry. Several spaces offer indoor and outdoor access, creating a resort-style wellness experience. The spa presents largely turnkey for an experienced operator following walkthrough and light updates. Seventh Floor – Wellness & Longevity Level Accessible by both elevator and stairwell, the seventh floor expands the wellness footprint and includes: • Existing fitness center • Movement studio suitable for yoga or Pilates • Former tanning studio with redevelopment potential • 13-room longevity lounge suite designed for modern wellness modalities The longevity suite can support IV therapy, hyperbaric chambers, cryotherapy, float tanks, red light therapy, infrared saunas, recovery services, and medical wellness programming. Four rooms include existing showers, and all treatment rooms throughout both levels are pre-plumbed with sinks and cabinetry, reducing build-out requirements. Flexible Operator Opportunity The layout allows for either: • Single flagship wellness operator controlling both floors, or • Multiple complementary wellness and fitness operators Resort Integration The spa level is located directly across the hallway from approximately 6,500 square feet connected to the pool deck, cabanas, and resort amenities, presenting opportunities to integrate dining, wellness, and hospitality experiences. Palms Place is connected to Palms Casino Resort, providing direct access to restaurants, entertainment venues, gaming, nightlife, and one of the most recognized hospitality brands in Las Vegas. This is a rare opportunity to establish a large-scale spa, longevity, and wellness destination within a fully operating luxury resort environment. Key Highlights • 26,000 SF Spa & Wellness Opportunity • Two-Level Spa and Longevity Facility • Rare Hammam Spa Amenity • 21 Total Treatment Rooms • Pre-Plumbed Treatment Rooms with Sinks & Cabinetry • Fitness, Pilates, and Longevity Lounge Potential • Direct Access to Palms Casino Resort Ideal Operator Profile This opportunity is well suited for established spa, longevity, recovery, or medical wellness operators seeking a flagship location within a fully integrated hospitality resort environment. The existing layout supports a wide range of concepts including: • Luxury destination spa operators • Medical spa and aesthetic wellness providers • Longevity and biohacking wellness brands • Recovery and performance therapy centers • Pilates, yoga, and boutique fitness operators • Integrated wellness ecosystems combining treatment, movement, and recovery With 21 treatment rooms across two levels, pre-plumbed infrastructure, wet spa facilities, and an existing hammam, the space offers a rare opportunity to activate a large-scale wellness destination with significantly reduced build-out requirements. Operators may choose to create a fully integrated wellness resort concept, or activate the space with complementary wellness brands operating across both floors. The location within Palms Place and direct connection to Palms Casino Resort provides access to a built-in customer base of hotel guests, residents, entertainment visitors, and Las Vegas locals. Confidential tours available for qualified operators. Financial capability and operational experience preferred.

Features and Amenities

  • Business Center
  • Fitness Center
  • Pool
  • Restaurant
  • Room Service
  • Spa
  • On-Site Retail
  • On-Site Bar
  • On-Site Casino
  • Meeting Event Space
  • Wedding Venue
  • Public Access Wifi
  • Hot Tub
  • Listing ID: 39630911

  • Date on Market: 3/2/2026

  • Last Updated:

  • Address: 4381 W Flamingo Rd, Las Vegas, NV 89103

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