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444 S Main St
Ann Arbor, MI 48104
444 S. Main Street · Office Property For Lease · 1,000 SF

Highlights

  • Purpose-Built for Therapy & Professional Use
  • Professional, Boutique Office Environment
  • Prime Downtown Ann Arbor Location

Property Overview

Position your practice in one of Ann Arbor’s most desirable and highly recognizable professional corridors. Located at 444 South Main Street, this well-maintained office building offers an exceptional opportunity for psychologists, therapists, social workers, and other professional service providers seeking a thoughtfully designed and welcoming environment for both clients and staff. Tenants appreciate the building’s boutique scale, which fosters a quiet and professional environment compared to larger, more impersonal office properties. The layout is particularly well-suited for individual practitioners or small group practices. The property combines the charm and character of Ann Arbor’s historic downtown with the functionality and efficiency required by modern professional users. The interior layout has been carefully configured to support counseling and clinical uses, featuring multiple private offices designed for confidentiality and comfort. Sound attenuation between rooms enhances privacy, while warm finishes and natural light contribute to a calm, professional atmosphere ideal for patient-facing practices. Shared spaces are thoughtfully arranged to create a seamless experience, including comfortable and private waiting areas and kitchenette space. Situated just steps from the vibrant Main Street district, the building benefits from immediate access to an abundance of restaurants, cafés, retail amenities, and public transportation, creating a highly convenient and attractive setting for clients and employees alike. Additional features include convenient on-site or nearby parking options, well-maintained common areas, and strong visibility along South Main Street—one of Ann Arbor’s primary north-south corridors. The property’s central location also provides quick access to the University of Michigan campus, surrounding residential neighborhoods, and major commuter routes, making it an ideal location for practitioners drawing clients from across town. This is a rare opportunity to lease space in a highly sought-after downtown location with a proven track record as a hub for mental health and professional services. Whether you are establishing a new practice or expanding an existing one, 444 South Main Street offers a turnkey environment designed to support productivity, privacy, and client comfort.

  • 24 Hour Access
  • Controlled Access
  • Air Conditioning

Property Facts

Building Type
Office
Year Built/Renovated
1901/2012
Building Height
3 Stories
Building Size
3,537 SF
Building Class
B
Typical Floor Size
962 SF
Unfinished Ceiling Height
9’
Parking
5 Surface Parking Spaces
  • Listing ID: 40133978

  • Date on Market: 4/13/2026

  • Last Updated:

  • Address: 444 S Main St, Ann Arbor, MI 48104

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