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Highlights

  • Prime street-level location at 452 First Street in Hoboken with strong visibility and accessibility.
  • Large glass storefront offering maximum street exposure for branding and customer engagement.
  • Situated in a dense Hoboken residential neighborhood with an established built-in customer base.

All Available Space(1)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste Unit 2
  • 630 SF
  • Negotiable
  • $81.00 /SF/YR $6.75 /SF/MO $51,030 /YR $4,253 /MO
  • Retail
  • Full Build-Out
  • Now

Prime street-level commercial space available for lease in the heart of Hoboken. This ±630 SF space is ideally suited for medical, wellness, office, or boutique retail use and is available for immediate occupancy. Previously occupied by Infinity Diagnostic Laboratories, the space is built out with multiple private rooms, a reception/waiting area, and dedicated utility infrastructure, making it especially attractive for medical or professional users looking for a turnkey setup. The layout offers a functional flow with a front-facing entrance, reception area, private treatment/exam rooms, and a rear workspace. The property benefits from strong street presence with large glass storefront windows that provide excellent natural light and signage visibility. Located on a well-trafficked corridor, the space offers consistent foot traffic and easy accessibility for clients and staff. Interior features include hardwood flooring throughout the main areas, a kitchenette with cabinetry, sink, and countertop workspace, and a private restroom. The space is also equipped with HVAC, multiple electrical circuits, and existing infrastructure to support a variety of business uses. The flexible layout allows for easy reconfiguration depending on tenant needs, whether maintaining the current medical-style setup or converting to a more open office or retail environment. Situated in one of Hoboken’s most desirable commercial neighborhoods, the location is surrounded by residential density, established businesses, and strong local demographics, providing a built-in customer base. Convenient access to public transportation, nearby parking options, and major thoroughfares further enhance the appeal. This is an excellent opportunity for a tenant seeking a clean, professional space with minimal upfront buildout required. Asking Rent: $4,250 per month Size: ±630 SF Location: Hoboken, NJ Availability: Immediate

  • Listed rate may not include certain utilities, building services and property expenses
  • Located in-line with other retail
  • Central Air and Heating
  • Private Restrooms
  • Secure Storage
  • Finished Ceilings: 11’
  • Display Window
  • Immediate occupancy
  • Former medical office (Infinity Diagnostics)
  • Reception / waiting area at entrance
  • Fully Built-Out as Professional Services Office
  • Space is in Excellent Condition
  • Partitioned Offices
  • High Ceilings
  • Plug & Play
  • Hardwood Floors
  • Smoke Detector
  • ±630 SF street-level commercial space
  • Turnkey layout with multiple private rooms
  • Private restroom
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste Unit 2 630 SF Negotiable $81.00 /SF/YR $6.75 /SF/MO $51,030 /YR $4,253 /MO Retail Full Build-Out Now

1st Floor, Ste Unit 2

Size
630 SF
Term
Negotiable
Rental Rate
$81.00 /SF/YR $6.75 /SF/MO $51,030 /YR $4,253 /MO
Space Use
Retail
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste Unit 2

Size 630 SF
Term Negotiable
Rental Rate $81.00 /SF/YR
Space Use Retail
Build-Out Full Build-Out
Available Now

Prime street-level commercial space available for lease in the heart of Hoboken. This ±630 SF space is ideally suited for medical, wellness, office, or boutique retail use and is available for immediate occupancy. Previously occupied by Infinity Diagnostic Laboratories, the space is built out with multiple private rooms, a reception/waiting area, and dedicated utility infrastructure, making it especially attractive for medical or professional users looking for a turnkey setup. The layout offers a functional flow with a front-facing entrance, reception area, private treatment/exam rooms, and a rear workspace. The property benefits from strong street presence with large glass storefront windows that provide excellent natural light and signage visibility. Located on a well-trafficked corridor, the space offers consistent foot traffic and easy accessibility for clients and staff. Interior features include hardwood flooring throughout the main areas, a kitchenette with cabinetry, sink, and countertop workspace, and a private restroom. The space is also equipped with HVAC, multiple electrical circuits, and existing infrastructure to support a variety of business uses. The flexible layout allows for easy reconfiguration depending on tenant needs, whether maintaining the current medical-style setup or converting to a more open office or retail environment. Situated in one of Hoboken’s most desirable commercial neighborhoods, the location is surrounded by residential density, established businesses, and strong local demographics, providing a built-in customer base. Convenient access to public transportation, nearby parking options, and major thoroughfares further enhance the appeal. This is an excellent opportunity for a tenant seeking a clean, professional space with minimal upfront buildout required. Asking Rent: $4,250 per month Size: ±630 SF Location: Hoboken, NJ Availability: Immediate

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Professional Services Office
  • Located in-line with other retail
  • Space is in Excellent Condition
  • Central Air and Heating
  • Partitioned Offices
  • Private Restrooms
  • High Ceilings
  • Secure Storage
  • Plug & Play
  • Finished Ceilings: 11’
  • Hardwood Floors
  • Display Window
  • Smoke Detector
  • Immediate occupancy
  • ±630 SF street-level commercial space
  • Former medical office (Infinity Diagnostics)
  • Turnkey layout with multiple private rooms
  • Reception / waiting area at entrance
  • Private restroom

Property Facts

Total Space Available 630 SF
No. Units 16
Property Type Multifamily
Property Subtype Apartment
Apartment Style Mid-Rise
Building Size 13,300 SF
Year Built 1950

About the Property

This retail space is located in the heart of Hoboken, surrounded by a vibrant mix of neighborhood-serving businesses, residential buildings, and steady foot traffic. The area is known for its walkability, strong local customer base, and proximity to popular dining, shopping, and waterfront amenities. Its setting within an active urban corridor makes it well-suited for retailers seeking visibility and a consistent flow of daily activity.

Exceptionally walkable
100/100
Fairly drivable
40/100
Exceptional public transit
90/100
Moderately bikeable
70/100

Nearby Major Retailers

Bank of America
Bank of America Mortgage
Citi
Just Salad
Johnny Rockets
CrossFit
Tiger Schulmann's Martial Arts
Starbucks
Whole Foods Market
ACME
  • Listing ID: 39877056

  • Date on Market: 3/23/2026

  • Last Updated:

  • Address: 450 1st St, Hoboken, NJ 07030

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