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Square One Office Plaza 4542 Ruffner St 1,354 - 5,306 SF of Space Available in San Diego, CA 92111

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HIGHLIGHTS

  • Centrally Located
  • Ability to accommodate various uses and sizes
  • World Class Food Within Walking Distance

ALL AVAILABLE SPACES(2)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste R140
  • 1,922 SF
  • Negotiable
  • $30.00 /SF/YR $2.50 /SF/MO $57,660 /YR $4,805 /MO
  • Office/Medical
  • Full Build-Out
  • January 01, 2026
  • Listed rate may not include certain utilities, building services and property expenses
  • 3 Private Offices
  • Central Air Conditioning
  • Fully Carpeted
  • After Hours HVAC Available
  • Open-Plan
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Balcony
  • High Ceilings
  • Atrium
  • 3rd Floor, Ste R320
  • 1,354-3,384 SF
  • Negotiable
  • $28.80 /SF/YR $2.40 /SF/MO $97,459 /YR $8,122 /MO
  • Office
  • Shell Space
  • February 01, 2026

Suite R320 at Square One Office Plaza offers approximately 3,384 square feet of move-in ready office space. Currently in shell condition, being built as a spec suite. 5% tenant rep commission on full term.

  • Listed lease rate plus proportional share of electrical cost
  • Central Air Conditioning
  • Elevator Access
  • Corner Space
  • Partitioned Offices
  • Reception Area
  • Fully Carpeted
  • After Hours HVAC Available
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste R140 1,922 SF Negotiable $30.00 /SF/YR $2.50 /SF/MO $57,660 /YR $4,805 /MO Office/Medical Full Build-Out January 01, 2026
3rd Floor, Ste R320 1,354-3,384 SF Negotiable $28.80 /SF/YR $2.40 /SF/MO $97,459 /YR $8,122 /MO Office Shell Space February 01, 2026

1st Floor, Ste R140

Size
1,922 SF
Term
Negotiable
Rental Rate
$30.00 /SF/YR $2.50 /SF/MO $57,660 /YR $4,805 /MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
January 01, 2026

3rd Floor, Ste R320

Size
1,354-3,384 SF
Term
Negotiable
Rental Rate
$28.80 /SF/YR $2.40 /SF/MO $97,459 /YR $8,122 /MO
Space Use
Office
Condition
Shell Space
Available
February 01, 2026

1st Floor, Ste R140

Size 1,922 SF
Term Negotiable
Rental Rate $30.00 /SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available January 01, 2026

  • Listed rate may not include certain utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 3 Private Offices
  • Space is in Excellent Condition
  • Central Air Conditioning
  • Balcony
  • Fully Carpeted
  • High Ceilings
  • After Hours HVAC Available
  • Atrium
  • Open-Plan

3rd Floor, Ste R320

Size 1,354-3,384 SF
Term Negotiable
Rental Rate $28.80 /SF/YR
Space Use Office
Condition Shell Space
Available February 01, 2026

Suite R320 at Square One Office Plaza offers approximately 3,384 square feet of move-in ready office space. Currently in shell condition, being built as a spec suite. 5% tenant rep commission on full term.

  • Listed lease rate plus proportional share of electrical cost
  • Partitioned Offices
  • Central Air Conditioning
  • Reception Area
  • Elevator Access
  • Fully Carpeted
  • Corner Space
  • After Hours HVAC Available

PROPERTY OVERVIEW

Landlord paying 5% Tenant Broker Commission! 4542 Ruffner Street and 7675 Dagget Street are two well-maintained, centrally located office buildings in Central San Diego. Each building boasts over 55,000 square feet of rentable building area broken up into various size spaces ranging from 1,500-18,000+ square feet. The property is within walking distance of Convoy Street, which features world-class Asian cuisine. Please check out our marketing video below for more information. Link to Marketing Video: https://vimeo.com/904973605

  • Property Manager on Site
  • Signage
  • Balcony

PROPERTY FACTS

Building Type
Office
Year Built/Renovated
1983/2004
Building Height
3 Stories
Building Size
55,690 SF
Building Class
B
Typical Floor Size
18,756 SF
Parking
150 Surface Parking Spaces
  • Listing ID: 34511771

  • Date on Market: 9/4/2025

  • Last Updated:

  • Address: 4542 Ruffner St, San Diego, CA 92111

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