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Highlights

  • Redeveloped RJ Reynolds power plant with 110,800 SF of mixed-use space in Innovation Quarter.
  • Flexible office and retail configurations with access to onsite tenant amenities.
  • LEED Gold-certified with modern infrastructure and sustainable design throughout.
  • Adjacent to Bailey Park and steps from Wake Forest University Health Sciences campus.
  • High ceilings, industrial character, and vibrant common areas foster collaboration.
  • Surrounded by dining, entertainment, and residential options in downtown Winston-Salem.

All Available Space(1)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor
  • 3,306 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now

±3,306 SF of cool industrial space with high ceilings, open floorplan, large windows, and ample storage Great signage opportunities in front and on Coal Pit side Co-located with high-traffic restaurants and bars Fantastic location in Innovation Quarter; close to Bailey Park, Link IQ Apartments, Plant 64 Apartments, Wake Forest School of Medicine & School of Health Sciences, and future Atrium WF Eye Institute Interior space features prep area, dishwashing station, grease trap, walk-in cooler, ample storage, multihead keg wall

  • Fits 9 - 27 People
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor 3,306 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office - Now

1st Floor

Size
3,306 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

1st Floor

Size 3,306 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out -
Available Now

±3,306 SF of cool industrial space with high ceilings, open floorplan, large windows, and ample storage Great signage opportunities in front and on Coal Pit side Co-located with high-traffic restaurants and bars Fantastic location in Innovation Quarter; close to Bailey Park, Link IQ Apartments, Plant 64 Apartments, Wake Forest School of Medicine & School of Health Sciences, and future Atrium WF Eye Institute Interior space features prep area, dishwashing station, grease trap, walk-in cooler, ample storage, multihead keg wall

  • Fits 9 - 27 People

Property Overview

Innovation Quarter is a dynamic, mixed-use innovation district in the heart of downtown Winston-Salem - designed to bring research, business, education, and community into close proximity. Where ideas connect and collaboration follows. Anchored by Wake Forest University School of Medicine, the district is home to more than 4,500 workers, 115 companies, and nearly 2,000 students. From biomedical science and clinical services to technology, data, and advanced materials, Innovation Quarter supports a diverse and growing community of thinkers, builders, and problem-solvers. Spanning more than 2 million square feet of office, lab, and academic space, the district blends cutting-edge facilities with walkable streets, residential living, and curated amenities. With direct access to greenway trails and a vibrant downtown, Innovation Quarter offers more than just workspace - it offers a connected, energized environment where ideas move faster and possibilities expand.

Property Facts

Building Type
Office
Year Built
2018
LoopNet Rating
4 Star
Building Height
5 Stories
Building Size
110,800 SF
Building Class
A
Typical Floor Size
22,160 SF
Parking
32 Surface Parking Spaces
Covered Parking

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 2nd
  • A Society
  • Professional, Scientific, and Technical Services
  • 1st
  • Alma Mexicana
  • Accommodation and Food Services
  • 2nd
  • CliftonLarsonAllen, LLP
  • Professional, Scientific, and Technical Services
  • 1st
  • Cugino Properties
  • Accommodation and Food Services
  • 1st
  • Dram and Draught
  • Accommodation and Food Services
  • 1st
  • F45 Training, Inc.
  • Arts, Entertainment, and Recreation
  • 2nd
  • Fluree
  • Information
  • 1st
  • Incendiary Brewing Company
  • Manufacturing
  • 2nd
  • McAdams
  • Professional, Scientific, and Technical Services
  • 1st
  • Smith Leonard Acct & Consultants
  • Professional, Scientific, and Technical Services

Sustainability

LEED Certified
Gold
LEED certification is a globally recognized symbol of sustainability achievement.

Sustainability

LEED Certification Developed by the U.S. Green Building Council (USGBC), the Leadership in Energy and Environmental Design (LEED) is a green building certification program focused on the design, construction, operation, and maintenance of green buildings, homes, and neighborhoods, which aims to help building owners and operators be environmentally responsible and use resources efficiently. LEED certification is a globally recognized symbol of sustainability achievement and leadership. To achieve LEED certification, a project earns points by adhering to prerequisites and credits that address carbon, energy, water, waste, transportation, materials, health and indoor environmental quality. Projects go through a verification and review process and are awarded points that correspond to a level of LEED certification: Platinum (80+ points) Gold (60-79 points) Silver (50-59 points) Certified (40-49 points)

Attachments

Floor Plan
Moderately walkable
70/100
Very drivable
80/100
Limited public transit
30/100
Moderately bikeable
60/100
  • Listing ID: 41174188

  • Date on Market: 7/6/2026

  • Last Updated:

  • Address: 486 N Patterson Ave, Winston-Salem, NC 27101

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