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Sublease Highlights

  • Newly constructed Class A life science building located directly across from Genentech's global headquarters in South San Francisco's biotech cluster.
  • Flexible full-floor opportunities with the ability to accommodate expansion needs and customize lab-to-office configurations.
  • Exceptional regional connectivity via US-101, I-280, BART, Caltrain, SF Bay Ferry, San Francisco International Airport approximately 10 minutes away.
  • Turnkey lab and office space delivered fully furnished with labs, casework, mobility stations, and operational research infrastructure.
  • Extensive structured parking with 265 stalls, EV charging capabilities, secure bicycle storage, and direct access to Bay Trail amenities.

All Available Spaces(2)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor
  • 6,000-29,000 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
  • Sublease space available from current tenant
  • Can be combined with additional space(s) for up to 58,000 SF of adjacent space
  • Laboratory
  • Conference Rooms
  • Central Air Conditioning
  • 3rd Floor
  • 6,000-29,000 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
  • Sublease space available from current tenant
  • Can be combined with additional space(s) for up to 58,000 SF of adjacent space
  • Laboratory
  • Conference Rooms
  • Central Air Conditioning
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor 6,000-29,000 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office - Now
3rd Floor 6,000-29,000 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office - Now

2nd Floor

Size
6,000-29,000 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

3rd Floor

Size
6,000-29,000 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

2nd Floor

Size 6,000-29,000 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out -
Available Now

  • Sublease space available from current tenant
  • Conference Rooms
  • Can be combined with additional space(s) for up to 58,000 SF of adjacent space
  • Central Air Conditioning
  • Laboratory

3rd Floor

Size 6,000-29,000 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out -
Available Now

  • Sublease space available from current tenant
  • Conference Rooms
  • Can be combined with additional space(s) for up to 58,000 SF of adjacent space
  • Central Air Conditioning
  • Laboratory

Property Overview

Designed for growing life science companies, our plug-and-play workspace enables your team to begin operations immediately, eliminating the time, cost, and disruption associated with traditional lab and office build-outs. Preserve valuable capital for research, hiring, and product development while benefiting from flexible lease terms and customizable rent structures that can evolve alongside your business. Whether you're advancing through critical R&D milestones, expanding your team, or preparing for your next funding round, you'll have the certainty of the space you need today with the flexibility to accommodate tomorrow's growth.

Property Facts

Building Type
Office
Year Built
2022
LoopNet Rating
5 Star
Building Height
5 Stories
Building Size
60,396 SF
Building Class
A
Typical Floor Size
12,079 SF
Parking
400 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • Multiple
  • Neuralink
  • Professional, Scientific, and Technical Services
Fairly walkable
40/100
Exceptionally drivable
100/100
Some public transit
40/100
Moderately bikeable
60/100
  • Listing ID: 41376347

  • Date on Market: 7/21/2026

  • Last Updated:

  • Address: 499 Forbes Blvd, South San Francisco, CA 94080

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