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One Market Exchange 515 E Main St 5,873 - 42,899 SF of 4-Star Office/Medical Space Available in Columbus, OH 43215

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HIGHLIGHTS

  • Medical and Creative Office Space
  • Newly renovated lobby, restrooms, and elevators
  • Exposed ceilings and concrete floors
  • Located downtown in the Market Exchange District near Nationwide Children’s Hospital and Grant Medical Center
  • Mix of private office and open collaboration space

ALL AVAILABLE SPACES(4)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor
  • 14,205 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

https://my.matterport.com/show/?m=p1VBap893FB

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Central Air and Heating
  • Wheelchair Accessible
  • Exposed ceilings and concrete floors
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Private Restrooms
  • Mix of private office and open collaboration space
  • Signage opportunity
  • 3rd Floor
  • 6,851 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • July 01, 2026

Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=FNmx11dAhYj

  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Free on-site parking and walkable access to dining
  • Open Floor Plan Layout
  • Central Air and Heating
  • Signage opportunities available
  • 4th Floor
  • 15,970 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • July 01, 2026

Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=ikZbEV6222C

  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Free on-site parking and walkable access to dining
  • Mostly Open Floor Plan Layout
  • Central Air and Heating
  • Signage opportunities available
  • 5th Floor, Ste 500
  • 5,873 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

https://my.matterport.com/show/?m=PD5XdAYjZnW

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Private Restrooms
  • Mix of private office and open collaboration space
  • Signage opportunity
  • Fully Built-Out as Standard Office
  • Central Air and Heating
  • Wheelchair Accessible
  • Exposed ceilings and concrete floors
  • Full 5th floor available
Space Size Term Rental Rate Space Use Condition Available
2nd Floor 14,205 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor 6,851 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out July 01, 2026
4th Floor 15,970 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out July 01, 2026
5th Floor, Ste 500 5,873 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

2nd Floor

Size
14,205 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

3rd Floor

Size
6,851 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
July 01, 2026

4th Floor

Size
15,970 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
July 01, 2026

5th Floor, Ste 500

Size
5,873 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor

Size 14,205 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

https://my.matterport.com/show/?m=p1VBap893FB

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Central Air and Heating
  • Private Restrooms
  • Wheelchair Accessible
  • Mix of private office and open collaboration space
  • Exposed ceilings and concrete floors
  • Signage opportunity

3rd Floor

Size 6,851 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available July 01, 2026

Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=FNmx11dAhYj

  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout
  • Space is in Excellent Condition
  • Central Air and Heating
  • Free on-site parking and walkable access to dining
  • Signage opportunities available

4th Floor

Size 15,970 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available July 01, 2026

Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=ikZbEV6222C

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Central Air and Heating
  • Free on-site parking and walkable access to dining
  • Signage opportunities available

5th Floor, Ste 500

Size 5,873 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

https://my.matterport.com/show/?m=PD5XdAYjZnW

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Central Air and Heating
  • Private Restrooms
  • Wheelchair Accessible
  • Mix of private office and open collaboration space
  • Exposed ceilings and concrete floors
  • Signage opportunity
  • Full 5th floor available

PROPERTY OVERVIEW

1 Market Exchange is a modern 56,856 SF five-story office building that has desirable professional and creative offices suites and a full floor available. The interior spaces contain concrete floors, exposed ceilings and ductwork, natural light and a mix of open and private office space. The building is a well-known landmark in the heart of the Market Exchange district in downtown Columbus walkable to nearby amenities and allows for convenient access to all major freeways. Free surface parking is available on site and adjacent to the building in a private parking lot.

  • Controlled Access
  • Security System

PROPERTY FACTS

Building Type
Office
Year Built
2001
LoopNet Rating
4 Star
Building Height
5 Stories
Building Size
66,587 SF
Building Class
A
Typical Floor Size
13,317 SF
Parking
128 Surface Parking Spaces
Covered Parking

SELECT TENANTS

  • FLOOR
  • TENANT NAME
  • Multiple
  • DesignGroup
  • 1st
  • Hanger Prosthetics & Orthotics, Inc
  • 1st
  • NECCO
  • 3rd
  • OhioGuidestone
Walk Score®
Very Walkable (82)
Bike Score®
Very Bikeable (73)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®
  • Listing ID: 33171305

  • Date on Market: 8/14/2025

  • Last Updated:

  • Address: 515 E Main St, Columbus, OH 43215

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