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Memorial Hermann Orthopedic & Surgery MOB 5420 West Loop S 1,149 - 24,622 SF of 4-Star Office/Medical Space Available in Bellaire, TX 77401

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HIGHLIGHTS

  • Excellent location
  • On-site security and property management
  • Abundant garage parking
  • Newly renovated common areas
  • Covered patient drop-off
  • No use restrictions

ALL AVAILABLE SPACES(7)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 1200
  • 2,599 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • January 01, 2027
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 1st Floor, Ste 1500
  • 1,747 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • Mostly Open Floor Plan Layout
  • 1st Floor, Ste 1700
  • 2,631 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Spec Suite
  • April 01, 2026

Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69
  • 1st Floor, Ste 1800
  • 1,149 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • 3rd Floor, Ste 3500
  • 3,238 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • 4th Floor, Ste 4100
  • 9,097 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
  • Space is in Excellent Condition
  • 4th Floor, Ste 4500
  • 4,161 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Easy access to I-610 and I-69
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 1200 2,599 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out January 01, 2027
1st Floor, Ste 1500 1,747 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
1st Floor, Ste 1700 2,631 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Spec Suite April 01, 2026
1st Floor, Ste 1800 1,149 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 3500 3,238 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
4th Floor, Ste 4100 9,097 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
4th Floor, Ste 4500 4,161 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

1st Floor, Ste 1200

Size
2,599 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
January 01, 2027

1st Floor, Ste 1500

Size
1,747 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 1700

Size
2,631 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Spec Suite
Available
April 01, 2026

1st Floor, Ste 1800

Size
1,149 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

3rd Floor, Ste 3500

Size
3,238 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

4th Floor, Ste 4100

Size
9,097 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

4th Floor, Ste 4500

Size
4,161 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 1200

Size 2,599 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available January 01, 2027

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition

1st Floor, Ste 1500

Size 1,747 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69

1st Floor, Ste 1700

Size 2,631 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Spec Suite
Available April 01, 2026

Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69

1st Floor, Ste 1800

Size 1,149 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69

3rd Floor, Ste 3500

Size 3,238 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69

4th Floor, Ste 4100

Size 9,097 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space

4th Floor, Ste 4500

Size 4,161 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
  • Easy access to I-610 and I-69

PROPERTY OVERVIEW

5420 West Loop South offers a premier medical office opportunity within the Bellaire submarket. This Class A, 4-story medical office building, was completed in 2008 and features 102,452 SF of rentable building area (RBA). Centrally located and directly connected to the Memorial Hermann Orthopedic & Spine Hospital, the property provides convenient access to I-610 and I-69, with a quick 17-minute commute to Texas Medical Center. The building offers on-site security and property management, covered patient drop-off, a gurney-accessible elevator, renovated common areas and abundant garage parking. With opportunities for monument and building signage, generous tenant improvement allowances, and flexible lease terms, 5420 West Loop S is an ideal location for medical practices seeking a high-quality, accessible, and well-amenitized space.

  • Bus Line
  • Signage
  • Skyway
  • Monument Signage

PROPERTY FACTS

Building Type
Office
Year Built
2007
LoopNet Rating
4 Star
Building Height
4 Stories
Building Size
102,452 SF
Building Class
A
Typical Floor Size
24,942 SF
Unfinished Ceiling Height
14’
Parking
5 Surface Parking Spaces
487 Covered Parking Spaces
  • Listing ID: 38620071

  • Date on Market: 6/12/2025

  • Last Updated:

  • Address: 5420 West Loop S, Bellaire, TX 77401

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