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Highlights

  • 5420 West Loop South is a Class A MOB offering customizable spaces and turnkey spec suite options ideally sized for growing practices.
  • Offer patients a welcoming arrival with renovated common areas, covered drop-off, and ample garage parking.
  • Optimistic economic data estimates total annual spending on healthcare within a 3-mile radius to increase by 21% from 2025 to 2030.
  • Connected to the Memorial Hermann Orthopedic & Spine Hospital for immediate referral opportunities, and only 17 minutes to the Texas Medical Center.
  • Highly convenient address at the crossing of I-610 and I-69, minutes to The Galleria/Uptown, Memorial, and other health-conscious residential hubs.
  • Take advantage of generous tenant improvement allowances with no use restrictions and flexible terms to create the ideal medical space.

All Available Spaces(7)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste 1200
  • 2,599 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • January 01, 2027
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 1st Floor, Ste 1500
  • 1,747 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • Mostly Open Floor Plan Layout
  • 1st Floor, Ste 1700
  • 2,631 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Spec Suite
  • Now

Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69
  • 1st Floor, Ste 1800
  • 1,149 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • 3rd Floor, Ste 3500
  • 3,238 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69
  • 4th Floor, Ste 4100
  • 9,097 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
  • Space is in Excellent Condition
  • 4th Floor, Ste 4500
  • 4,161 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Easy access to I-610 and I-69
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste 1200 2,599 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out January 01, 2027
1st Floor, Ste 1500 1,747 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
1st Floor, Ste 1700 2,631 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Spec Suite Now
1st Floor, Ste 1800 1,149 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 3500 3,238 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
4th Floor, Ste 4100 9,097 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
4th Floor, Ste 4500 4,161 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

1st Floor, Ste 1200

Size
2,599 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
January 01, 2027

1st Floor, Ste 1500

Size
1,747 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste 1700

Size
2,631 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Spec Suite
Available
Now

1st Floor, Ste 1800

Size
1,149 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 3500

Size
3,238 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

4th Floor, Ste 4100

Size
9,097 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

4th Floor, Ste 4500

Size
4,161 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste 1200

Size 2,599 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available January 01, 2027

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition

1st Floor, Ste 1500

Size 1,747 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69

1st Floor, Ste 1700

Size 2,631 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Spec Suite
Available Now

Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Mostly Open Floor Plan Layout
  • Easy access to I-610 and I-69

1st Floor, Ste 1800

Size 1,149 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69

3rd Floor, Ste 3500

Size 3,238 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Easy access to I-610 and I-69

4th Floor, Ste 4100

Size 9,097 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space

4th Floor, Ste 4500

Size 4,161 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 13,258 SF of adjacent space
  • Easy access to I-610 and I-69

Property Overview

5420 West Loop South offers a premier medical office opportunity within the Bellaire submarket. This Class A, 4-story medical office building (MOB) was completed in 2008 and features 102,452 square feet of rentable building area (RBA). Centrally located and directly connected to the Memorial Hermann Orthopedic & Spine Hospital, the property provides convenient access to Interstates 610 and 69, with a quick 17-minute commute to Texas Medical Center. The building offers on-site security and property management, covered patient drop-off, a gurney-accessible elevator, renovated common areas, and abundant garage parking. With opportunities for monument and building signage, generous tenant improvement allowances, and flexible lease terms, 5420 West Loop S is an ideal location for medical practices seeking a high-quality, accessible, and well-amenitized space About Ownership: Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

  • Bio-Tech/ Lab Space
  • Bus Line
  • Courtyard
  • Signage
  • Skyway
  • Wheelchair Accessible
  • Reception
  • Secure Storage
  • Monument Signage

Property Facts

Building Type
Office
Year Built
2007
LoopNet Rating
4 Star
Building Height
4 Stories
Building Size
102,452 SF
Building Class
A
Typical Floor Size
24,942 SF
Unfinished Ceiling Height
14’
Parking
5 Surface Parking Spaces
395 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • Multiple
  • Memorial Hermann Sports Medicine
  • Health Care and Social Assistance
  • 4th
  • The LASIK Vision Institute
  • Health Care and Social Assistance
  • Multiple
  • UT Physicians
  • Health Care and Social Assistance
Moderately walkable
60/100
Exceptionally drivable
100/100
Some public transit
50/100
  • Listing ID: 38620071

  • Date on Market: 6/12/2025

  • Last Updated:

  • Address: 5420 West Loop S, Bellaire, TX 77401

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