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Memorial Hermann Orthopedic & Spine MOB 5420 West Loop S 1,149 - 24,622 SF of 4-Star Office/Medical Space Available in Bellaire, TX 77401



Highlights
- 5420 West Loop South is a Class A MOB offering customizable spaces and turnkey spec suite options ideally sized for growing practices.
- Offer patients a welcoming arrival with renovated common areas, covered drop-off, and ample garage parking.
- Optimistic economic data estimates total annual spending on healthcare within a 3-mile radius to increase by 21% from 2025 to 2030.
- Connected to the Memorial Hermann Orthopedic & Spine Hospital for immediate referral opportunities, and only 17 minutes to the Texas Medical Center.
- Highly convenient address at the crossing of I-610 and I-69, minutes to The Galleria/Uptown, Memorial, and other health-conscious residential hubs.
- Take advantage of generous tenant improvement allowances with no use restrictions and flexible terms to create the ideal medical space.
All Available Spaces(7)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Build-Out
- Available
- Fully Built-Out as Standard Medical Space
- Space is in Excellent Condition
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Fully Built-Out as Standard Medical Space
- Easy access to I-610 and I-69
- Mostly Open Floor Plan Layout
Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Mostly Open Floor Plan Layout
- Easy access to I-610 and I-69
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Fully Built-Out as Standard Medical Space
- Easy access to I-610 and I-69
- Fully Built-Out as Standard Medical Space
- Easy access to I-610 and I-69
- Fully Built-Out as Standard Medical Space
- Can be combined with additional space(s) for up to 13,258 SF of adjacent space
- Space is in Excellent Condition
- Fully Built-Out as Standard Medical Space
- Space is in Excellent Condition
- Easy access to I-610 and I-69
- Mostly Open Floor Plan Layout
- Can be combined with additional space(s) for up to 13,258 SF of adjacent space
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
| 1st Floor, Ste 1200 | 2,599 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | January 01, 2027 |
| 1st Floor, Ste 1500 | 1,747 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
| 1st Floor, Ste 1700 | 2,631 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Spec Suite | Now |
| 1st Floor, Ste 1800 | 1,149 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
| 3rd Floor, Ste 3500 | 3,238 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
| 4th Floor, Ste 4100 | 9,097 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
| 4th Floor, Ste 4500 | 4,161 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
1st Floor, Ste 1200
| Size |
| 2,599 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| January 01, 2027 |
1st Floor, Ste 1500
| Size |
| 1,747 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
1st Floor, Ste 1700
| Size |
| 2,631 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Spec Suite |
| Available |
| Now |
1st Floor, Ste 1800
| Size |
| 1,149 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
3rd Floor, Ste 3500
| Size |
| 3,238 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
4th Floor, Ste 4100
| Size |
| 9,097 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
4th Floor, Ste 4500
| Size |
| 4,161 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
1st Floor, Ste 1200
| Size | 2,599 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | January 01, 2027 |
- Fully Built-Out as Standard Medical Space
- Space is in Excellent Condition
1st Floor, Ste 1500
| Size | 1,747 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | Now |
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Fully Built-Out as Standard Medical Space
- Mostly Open Floor Plan Layout
- Easy access to I-610 and I-69
1st Floor, Ste 1700
| Size | 2,631 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Spec Suite |
| Available | Now |
Spec Suite Available Q2 2026. Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Mostly Open Floor Plan Layout
- Easy access to I-610 and I-69
1st Floor, Ste 1800
| Size | 1,149 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | Now |
Located in Class A medical office building connected to Memorial Hermann Orthopedic & Spine Hospital. Features Modern lobby with attendant, covered patient drop-off, and abundant garage parking
- Fully Built-Out as Standard Medical Space
- Easy access to I-610 and I-69
3rd Floor, Ste 3500
| Size | 3,238 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | Now |
- Fully Built-Out as Standard Medical Space
- Easy access to I-610 and I-69
4th Floor, Ste 4100
| Size | 9,097 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | Now |
- Fully Built-Out as Standard Medical Space
- Space is in Excellent Condition
- Can be combined with additional space(s) for up to 13,258 SF of adjacent space
4th Floor, Ste 4500
| Size | 4,161 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Build-Out | Full Build-Out |
| Available | Now |
- Fully Built-Out as Standard Medical Space
- Mostly Open Floor Plan Layout
- Space is in Excellent Condition
- Can be combined with additional space(s) for up to 13,258 SF of adjacent space
- Easy access to I-610 and I-69
Property Overview
5420 West Loop South offers a premier medical office opportunity within the Bellaire submarket. This Class A, 4-story medical office building (MOB) was completed in 2008 and features 102,452 square feet of rentable building area (RBA). Centrally located and directly connected to the Memorial Hermann Orthopedic & Spine Hospital, the property provides convenient access to Interstates 610 and 69, with a quick 17-minute commute to Texas Medical Center. The building offers on-site security and property management, covered patient drop-off, a gurney-accessible elevator, renovated common areas, and abundant garage parking. With opportunities for monument and building signage, generous tenant improvement allowances, and flexible lease terms, 5420 West Loop S is an ideal location for medical practices seeking a high-quality, accessible, and well-amenitized space About Ownership: Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com
- Bio-Tech/ Lab Space
- Bus Line
- Courtyard
- Signage
- Skyway
- Wheelchair Accessible
- Reception
- Secure Storage
- Monument Signage
Property Facts
Select Tenants
- Floor
- Tenant Name
- Industry
- Multiple
- Memorial Hermann Sports Medicine
- Health Care and Social Assistance
- 4th
- The LASIK Vision Institute
- Health Care and Social Assistance
- Multiple
- UT Physicians
- Health Care and Social Assistance
Presented by
Memorial Hermann Orthopedic & Spine MOB | 5420 West Loop S
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