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640 Interstate 45 S - Medical Office Building- 640 IH 45 South 9,387 SF Health Care Building Offered at $2,995,000 in Huntsville, TX 77340

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INVESTMENT HIGHLIGHTS

  • Owner/User or Lease Opportunity – Flexible options: acquire for $2,995,000 or lease at $23.00/SF NNN.
  • Strong Site Fundamentals – 1.48-acre parcel with excellent frontage and signage visibility on Interstate 45.
  • Proximity to Medical Anchors – Minutes from Huntsville Memorial Hospital and other established medical providers.
  • Purpose-Built Medical Facility – 9,387 SF building constructed in 2007 as a cancer treatment center, with exam rooms, reception, offices, and storage.
  • Regional Connectivity – 30 minutes to The Woodlands, 1 hour to Houston, direct access north to Dallas via IH-45.
  • Value-Add Potential – Ideal for owner-users seeking control, or investors repositioning for medical tenancy with stable long-term returns.

EXECUTIVE SUMMARY

640 IH-45 South is a 9,387 SF medical office building purpose-built in 2007 as a cancer treatment center. Sitting on a 1.48-acre site with excellent ingress/egress and direct visibility along Interstate 45, this property offers unmatched accessibility for patients, staff, and visitors traveling between Houston, Dallas, and The Woodlands.
The single-story design features a functional medical build-out with reception, exam/treatment rooms, offices, and storage, all optimized for efficient patient flow. Parking is abundant, with 20 front spaces dedicated to patients and visitors and separate staff parking in the rear, ensuring smooth operations for high-volume practices.
This opportunity is available for sale at $2,995,000 or for lease at $23.00/SF NNN, making it ideal for:
Medical clinics and specialty practices (oncology, imaging, dental, orthopedic, pediatric)
General office or professional users seeking a high-quality, high-visibility facility
Owner/users wanting long-term control of a premier Huntsville healthcare location
Highlights:
9,387 SF single-story medical office on 1.48 acres
Built 2007, purpose-designed for medical use
High visibility along IH-45 with strong regional traffic counts
20 front parking spaces + rear staff parking
Minutes from Huntsville Memorial Hospital and Sam Houston State University
Easy access to The Woodlands (30 min) and Houston metro (1 hr)
With Huntsville’s continued growth, strong healthcare demand, and regional connectivity, this property represents an outstanding opportunity for both investors and medical professionals.

PROPERTY FACTS

Price $2,995,000
Price Per Bed $149,750
Sale Type Investment or Owner User
Property Type
Health Care
  • Healthcare Assisted Living
  • Healthcare Hospital
  • Healthcare Rehabilitation Center
Building Class B
Lot Size 1.52 AC
Building Size 9,387 SF
No. Beds 20
No. Stories 1
Year Built 2007

AMENITIES

  • Wheelchair Accessible

PROPERTY TAXES

PROPERTY TAXES

Parcel Number
32833
Land Assessment
$205,880
Improvements Assessment
$1,228,210
Total Assessment
$1,434,090
  • Listing ID: 37955743

  • Date on Market: 10/5/2025

  • Last Updated:

  • Address: 640 Interstate 45 S, Huntsville, TX 77340

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