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Highlights

  • Professional medical/office condo
  • Recently updated
  • Private entrance

All Available Space(1)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 1st Floor
  • 1,350 SF
  • Negotiable
  • $13.00 /SF/YR $1.08 /SF/MO $17,550 /YR $1,463 /MO
  • Office
  • -
  • March 21, 2026

Prime professional/medical office condo available for lease in the highly desirable Village of Williamsville, located along the Main Street corridor with convenient access to I-90. This 1,350 SF office suite offers a highly efficient layout ideal for medical, wellness, or professional office users. The space features a private entrance and welcoming foyer, leading into a dedicated waiting area and administrative/business office. The layout features multiple private offices and exam rooms, as well as a storage room and a kitchenette. The suite is equipped with existing medical/gas line infrastructure, offering potential for continued medical use or specialty buildouts, subject to tenant verification and requirements. The space has been well maintained and recently updated, including new HVAC (furnace & A/C), updated flooring, bathroom improvements, and fresh paint, providing a clean and modern environment for both staff and clients. Situated within a professional office park, the property offers ample on-site parking, easy accessibility, and strong surrounding demographics. The location provides excellent visibility and proximity to retail, dining, and residential neighborhoods, making it ideal for businesses seeking both convenience and a professional setting. 1,350 SF available Base Rent: $13.00/SF NNN Estimated NNN Expenses (Taxes, Insurance & CAM): $5.34/SF Estimated Total Occupancy Cost: $18.34/SF

  • Lease rate does not include utilities, property expenses or building services
  • Fits 4 - 11 People
Space Size Term Rental Rate Space Use Condition Available
1st Floor 1,350 SF Negotiable $13.00 /SF/YR $1.08 /SF/MO $17,550 /YR $1,463 /MO Office - March 21, 2026

1st Floor

Size
1,350 SF
Term
Negotiable
Rental Rate
$13.00 /SF/YR $1.08 /SF/MO $17,550 /YR $1,463 /MO
Space Use
Office
Condition
-
Available
March 21, 2026

1st Floor

Size 1,350 SF
Term Negotiable
Rental Rate $13.00 /SF/YR
Space Use Office
Condition -
Available March 21, 2026

Prime professional/medical office condo available for lease in the highly desirable Village of Williamsville, located along the Main Street corridor with convenient access to I-90. This 1,350 SF office suite offers a highly efficient layout ideal for medical, wellness, or professional office users. The space features a private entrance and welcoming foyer, leading into a dedicated waiting area and administrative/business office. The layout features multiple private offices and exam rooms, as well as a storage room and a kitchenette. The suite is equipped with existing medical/gas line infrastructure, offering potential for continued medical use or specialty buildouts, subject to tenant verification and requirements. The space has been well maintained and recently updated, including new HVAC (furnace & A/C), updated flooring, bathroom improvements, and fresh paint, providing a clean and modern environment for both staff and clients. Situated within a professional office park, the property offers ample on-site parking, easy accessibility, and strong surrounding demographics. The location provides excellent visibility and proximity to retail, dining, and residential neighborhoods, making it ideal for businesses seeking both convenience and a professional setting. 1,350 SF available Base Rent: $13.00/SF NNN Estimated NNN Expenses (Taxes, Insurance & CAM): $5.34/SF Estimated Total Occupancy Cost: $18.34/SF

  • Lease rate does not include utilities, property expenses or building services
  • Fits 4 - 11 People

Property Overview

Prime professional/medical office condo available for lease in the highly desirable Village of Williamsville, located along the Main Street corridor with convenient access to I-90. This 1,350 SF office suite offers a highly efficient layout ideal for medical, wellness, or professional office users. The space features a private entrance and welcoming foyer, leading into a dedicated waiting area and administrative/business office. The layout features multiple private offices and exam rooms, as well as a storage room and a kitchenette. The suite is equipped with existing medical/gas line infrastructure, offering potential for continued medical use or specialty buildouts, subject to tenant verification and requirements. The space has been well maintained and recently updated, including new HVAC (furnace & A/C), updated flooring, bathroom improvements, and fresh paint, providing a clean and modern environment for both staff and clients. Situated within a professional office park, the property offers ample on-site parking, easy accessibility, and strong surrounding demographics. The location provides excellent visibility and proximity to retail, dining, and residential neighborhoods, making it ideal for businesses seeking both convenience and a professional setting. 1,350 SF available Base Rent: $13.00/SF NNN Estimated NNN Expenses (Taxes, Insurance & CAM): $5.34/SF Estimated Total Occupancy Cost: $18.34/SF

  • 24 Hour Access
  • Air Conditioning

Property Facts

Building Type
Office
Year Built
1994
Building Height
1 Story
Building Size
8,100 SF
Building Class
B
Typical Floor Size
1,350 SF
Parking
30 Surface Parking Spaces
Covered Parking

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • Advanced Care Physical Therapy
  • Health Care and Social Assistance
  • 1st
  • Dr. Mary C Collard, DDS
  • Health Care and Social Assistance
  • 1st
  • Greater Niagara Oral Surgery
  • Health Care and Social Assistance
  • 1st
  • Somsa
  • Public Administration
  • 1st
  • Suburban Oral & Maxillofacial Surgery
  • Health Care and Social Assistance
Fairly walkable
40/100
Exceptionally drivable
100/100
Limited public transit
30/100
Somewhat bikeable
30/100
  • Listing ID: 39852936

  • Date on Market: 3/20/2026

  • Last Updated:

  • Address: 6490 Main St, Buffalo, NY 14221

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