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MOB Highway 281 & Encino Rio 29,767 - 59,815 SF of 4-Star Office/Medical Space Available in San Antonio, TX 78258
Highlights
- Two-story Class A medical office building with modern design and efficient layouts.
- Ample parking with a ratio of 5.5 spaces per 1,000 SF for patient and staff convenience.
- Positioned in a rapidly growing area with strong demographics and healthcare demand.
- Highly visible location at U.S. Highway 281 and Encino Rio with strong traffic counts.
- Build-to-suit opportunities available with additional contiguous land for development.
- Easy access to Loop 1604 and major retail, dining, and medical facilities nearby.
All Available Spaces(2)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Build-Out
- Available
This upcoming Class A medical office building offers a rare pre-leasing opportunity in one of San Antonio’s most dynamic growth corridors. Located at the highly visible intersection of U.S. Highway 281 and Encino Rio, the two-story facility is designed with modern healthcare users in mind, providing efficient layouts and excellent ingress and egress for both patients and staff. The property will feature a contemporary design, ample natural light, and convenient access to major transportation routes, including Loop 1604 and U.S. Highway 281. With a parking ratio of 5.5 spaces per 1,000 SF, the site ensures ease of access for visitors and employees. Additional contiguous land is available for build-to-suit opportunities, and ownership offers a limited partnership investment option for qualified tenants. Situated within a thriving trade area, the location benefits from strong population growth, high household incomes, and proximity to major retail, dining, and healthcare facilities. This makes it an exceptional choice for medical professionals seeking to establish or expand their presence in a high-demand market.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Easy access to Loop 1604 and major retail
- Build-to-suit opportunities available
- Mostly Open Floor Plan Layout
- Two-story Class A medical office building
- Positioned in a rapidly growing area
This upcoming Class A medical office building offers a rare pre-leasing opportunity in one of San Antonio’s most dynamic growth corridors. Located at the highly visible intersection of U.S. Highway 281 and Encino Rio, the two-story facility is designed with modern healthcare users in mind, providing efficient layouts and excellent ingress and egress for both patients and staff. The property will feature a contemporary design, ample natural light, and convenient access to major transportation routes, including Loop 1604 and U.S. Highway 281. With a parking ratio of 5.5 spaces per 1,000 SF, the site ensures ease of access for visitors and employees. Additional contiguous land is available for build-to-suit opportunities, and ownership offers a limited partnership investment option for qualified tenants. Situated within a thriving trade area, the location benefits from strong population growth, high household incomes, and proximity to major retail, dining, and healthcare facilities. This makes it an exceptional choice for medical professionals seeking to establish or expand their presence in a high-demand market.
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Easy access to Loop 1604 and major retail
- Build-to-suit opportunities available
- Mostly Open Floor Plan Layout
- Two-story Class A medical office building
- Positioned in a rapidly growing area
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
| 1st Floor | 30,048 SF | Negotiable | $39.00 /SF/YR $3.25 /SF/MO $1,171,872 /YR $97,656 /MO | Office/Medical | - | January 01, 2028 |
| 2nd Floor | 29,767 SF | Negotiable | $39.00 /SF/YR $3.25 /SF/MO $1,160,913 /YR $96,743 /MO | Office/Medical | - | January 01, 2028 |
1st Floor
| Size |
| 30,048 SF |
| Term |
| Negotiable |
| Rental Rate |
| $39.00 /SF/YR $3.25 /SF/MO $1,171,872 /YR $97,656 /MO |
| Space Use |
| Office/Medical |
| Build-Out |
| - |
| Available |
| January 01, 2028 |
2nd Floor
| Size |
| 29,767 SF |
| Term |
| Negotiable |
| Rental Rate |
| $39.00 /SF/YR $3.25 /SF/MO $1,160,913 /YR $96,743 /MO |
| Space Use |
| Office/Medical |
| Build-Out |
| - |
| Available |
| January 01, 2028 |
1st Floor
| Size | 30,048 SF |
| Term | Negotiable |
| Rental Rate | $39.00 /SF/YR |
| Space Use | Office/Medical |
| Build-Out | - |
| Available | January 01, 2028 |
This upcoming Class A medical office building offers a rare pre-leasing opportunity in one of San Antonio’s most dynamic growth corridors. Located at the highly visible intersection of U.S. Highway 281 and Encino Rio, the two-story facility is designed with modern healthcare users in mind, providing efficient layouts and excellent ingress and egress for both patients and staff. The property will feature a contemporary design, ample natural light, and convenient access to major transportation routes, including Loop 1604 and U.S. Highway 281. With a parking ratio of 5.5 spaces per 1,000 SF, the site ensures ease of access for visitors and employees. Additional contiguous land is available for build-to-suit opportunities, and ownership offers a limited partnership investment option for qualified tenants. Situated within a thriving trade area, the location benefits from strong population growth, high household incomes, and proximity to major retail, dining, and healthcare facilities. This makes it an exceptional choice for medical professionals seeking to establish or expand their presence in a high-demand market.
- Lease rate does not include utilities, property expenses or building services
- Mostly Open Floor Plan Layout
- Space is in Excellent Condition
- Two-story Class A medical office building
- Easy access to Loop 1604 and major retail
- Positioned in a rapidly growing area
- Build-to-suit opportunities available
2nd Floor
| Size | 29,767 SF |
| Term | Negotiable |
| Rental Rate | $39.00 /SF/YR |
| Space Use | Office/Medical |
| Build-Out | - |
| Available | January 01, 2028 |
This upcoming Class A medical office building offers a rare pre-leasing opportunity in one of San Antonio’s most dynamic growth corridors. Located at the highly visible intersection of U.S. Highway 281 and Encino Rio, the two-story facility is designed with modern healthcare users in mind, providing efficient layouts and excellent ingress and egress for both patients and staff. The property will feature a contemporary design, ample natural light, and convenient access to major transportation routes, including Loop 1604 and U.S. Highway 281. With a parking ratio of 5.5 spaces per 1,000 SF, the site ensures ease of access for visitors and employees. Additional contiguous land is available for build-to-suit opportunities, and ownership offers a limited partnership investment option for qualified tenants. Situated within a thriving trade area, the location benefits from strong population growth, high household incomes, and proximity to major retail, dining, and healthcare facilities. This makes it an exceptional choice for medical professionals seeking to establish or expand their presence in a high-demand market.
- Lease rate does not include utilities, property expenses or building services
- Mostly Open Floor Plan Layout
- Space is in Excellent Condition
- Two-story Class A medical office building
- Easy access to Loop 1604 and major retail
- Positioned in a rapidly growing area
- Build-to-suit opportunities available
Property Overview
The property is located at the intersection of U.S. Highway 281 and Encino Rio in San Antonio, Texas. It is planned as a two-story medical office building with a total size of 59,815 SF and an anticipated delivery in Q1 2028. The site offers ingress and egress from Highway 281 and is within close proximity to Loop 1604. The surrounding area includes retail centers, healthcare facilities, and residential neighborhoods.
Property Facts
Presented by
MOB | Highway 281 & Encino Rio
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