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Hwy 601 & St Matthews
Orangeburg, SC 29118
±102-Acre Mixed-Use Development · Land For Sale · 102.00 AC

Investment Highlights

  • Highly visible development tract with frontage along a primary commercial corridor serving Orangeburg’s strongest demand center.
  • Flexible land plan that accommodates residential, regional retail, outparcels, office, and service-based uses.
  • General Commercial zoning and on-site utilities reduce entitlement timelines and support efficient development execution.
  • Immediate access to I-26 and proximity to major employers supporting strong daytime population and retail performance.
  • Established traffic flows and proximity to education, healthcare, and industrial hubs ensure consistent long-term demand.

Property Facts

Sale Type Investment
No. Lots 1
Property Type Land
Property Subtype Commercial
Proposed Use
Commercial
  • Mixed Use
  • Storefront, Retail or Residential
Total Lot Size 102.00 AC
Zoning CC - Commercial

1 Lot Available

Lot

Lot Size 102.00 AC

Residential (proposed) - ±66.5 acres (including ±8-acre wetlands) Office/ neighborhood commercial (proposed) - ±3.5 acres Anchor/ big box retail (proposed) - ±25 acres Retail out parcel (proposed) - ±4.5 acres Convenience store (proposed) - ±2.5 acre

Description

Opportunity This ±102-acre mixed-use development site in Orangeburg, South Carolina, offers a versatile opportunity for residential, retail and commercial development within one of the market’s active corridors. Featuring strong frontage on Hwy 601 (St. Matthews Road) and on-site utilities, the proposed site plan includes residential acreage, big-box retail, outparcels, office/neighborhood commercial parcels and a convenience store pad. Its proximity to major employers, educational institutions and expanding industrial operations enhances long-term demand drivers, making it an attractive investment for developers seeking opportunities in a growing regional market. Location The St. Matthews Road corridor in Orangeburg, SC, presents a highly attractive market for retail property buyers thanks to its strategic location and robust commercial activity. The area benefits from easy access to I-26 Exit 145 (±55,200 VPD), nearby Orangeburg-Calhoun Technical College and MUSC Health, creating a built-in customer base. Currently zoned as General Commercial, this property is located within a growing business corridor supported by established retail, healthcare, and financial services, making it a strong development opportunity in Orangeburg.

Property Taxes

Property Taxes

Parcel Numbers
Multiple
  • 0174-08-03-002.000
  • 0181-05-02-004.000
Land Assessment
$870
Improvements Assessment
$0
Total Assessment
$870
  • Listing ID: 39807792

  • Date on Market: 3/17/2026

  • Last Updated:

  • Address: Hwy 601 & St Matthews, Orangeburg, SC 29118

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