317-319 S Main St 10,841 SF 100% Leased Retail Building Dayton, OH 45402 $299,000 ($27.58/SF)

This versatile Office/Retail/Warehouse mixed-use property sits in an excellent downtown location with immediate access to Interstate 75 and Route 35, making it ideal for businesses that value convenience, visibility, and regional connectivity. Positioned in Dayton’s Urban Business District (UBD), the property supports a broad range of permitted uses, including work-live units, offices (general and medical), retail, service establishments, daycare (child and adult), hotels, wholesale distribution (indoor), light manufacturing, research/development facilities, cultural institutions, assembly halls, churches, libraries, and even marijuana establishments (laboratory or dispensary). This zoning flexibility opens doors for diverse operations and future adaptability.
Property Features: First-floor retail space — perfect for customer-facing businesses; Second- and third-floor office suites — ideal for professional services;
First- and second-floor warehouse with overhead door access; Private parking lot in the rear — a major advantage in downtown; New flat roof installed in 2026!
Total building size is approximately 10,841 square feet on a 0.17-acre lot. The configuration suits a wide array of users: service, contractor, or repair businesses; retail and distribution operations; work-live setups; insurance, accounting, or attorney offices; medical practices; cell phone/computer sales & service; consulting firms; and mail-order (retail or wholesale) companies.
The property stands in the vibrant core of downtown Dayton, directly adjacent to City Day Community School (320 S Main Street) and near Chaminade-Julienne Catholic High School, Sinclair Community College, the Dayton Convention Center, and the lively Oregon District—a hub of dining, entertainment, and nightlife that draws locals and visitors year-round.
Easy interstate access puts the entire Miami Valley region within quick reach, while the surrounding area benefits from ongoing revitalization. Downtown Dayton has seen more than $2 billion in public and private investments since 2010, including new housing, adaptive-reuse projects, tech hubs, and business growth. The greater downtown area supports thousands of employees, residents, students, and millions of annual visitors through conventions, events, and cultural attractions.
Strong Demographics & Commercial Market Potential as Dayton’s downtown ZIP code (45402) serves a compact but growing urban population with a citywide population of approximately 136,000 and a metropolitan statistical area exceeding 822,000 residents. The median age hovers around 34 years, supporting a young, active workforce and consumer base. Median household income in the immediate area is in the $45,000–$48,000 range, with broader economic drivers including education (Sinclair and area schools), healthcare, logistics, advanced manufacturing, and proximity to Wright-Patterson Air Force Base.
This is a chance to secure a mixed-use asset in a revitalizing downtown with flexible zoning, modern updates (new roof!), private parking, and unmatched accessibility. Contact us today to schedule a private tour and explore how this property can power your business vision in the heart of Dayton’s renaissance.