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35 Gatehouse Dr
Waltham, MA 02451
Office Property For Lease · 395,000 SF

Highlights

  • Modern infrastructure, robust utility systems, and flexible floor plates to support specialized lab build-outs.
  • Located just minutes from downtown Waltham and 17 miles from Logan International Airport.
  • Ample on-site parking, landscaped grounds, and proximity to major highways.
  • Mix of office, laboratory, and flex space, making it ideal for pharmaceutical, biotech, and high-tech tenants.

Property Overview

35 Gatehouse Drive is a premier life science and office campus located in Waltham, Massachusetts, within the thriving Route 128 biotech corridor. Built in 1999 and spanning approximately 298,000 square feet across three stories, this Class A facility is designed to accommodate cutting-edge research and development operations. The property sits on a 42.85-acre site and offers a mix of office, laboratory, and flex space, making it ideal for pharmaceutical, biotech, and high-tech tenants. Current occupants include leading firms such as AstraZeneca and Morphic Therapeutic, underscoring its reputation as a hub for innovation. The building features modern infrastructure, robust utility systems, and flexible floor plates to support specialized lab build-outs. Ample on-site parking, landscaped grounds, and proximity to major highways—including I-95/Route 128—ensure excellent accessibility. Located just minutes from downtown Waltham and 17 miles from Logan International Airport, 35 Gatehouse Drive combines convenience, scalability, and world-class amenities for companies seeking a strategic presence in Greater Boston’s life science cluster

  • Bio-Tech/ Lab Space
  • Fenced Lot
  • Signage
  • LEED Certified - Gold
  • Energy Star Labeled
  • Car Charging Station

Property Facts

Building Type
Office
Year Built
2009
LoopNet Rating
4 Star
Building Height
4 Stories
Building Size
395,000 SF
Building Class
A
Typical Floor Size
125,000 SF

Sustainability

LEED Certified
Gold
LEED certification is a globally recognized symbol of sustainability achievement.

Sustainability

LEED Certification Developed by the U.S. Green Building Council (USGBC), the Leadership in Energy and Environmental Design (LEED) is a green building certification program focused on the design, construction, operation, and maintenance of green buildings, homes, and neighborhoods, which aims to help building owners and operators be environmentally responsible and use resources efficiently. LEED certification is a globally recognized symbol of sustainability achievement and leadership. To achieve LEED certification, a project earns points by adhering to prerequisites and credits that address carbon, energy, water, waste, transportation, materials, health and indoor environmental quality. Projects go through a verification and review process and are awarded points that correspond to a level of LEED certification: Platinum (80+ points) Gold (60-79 points) Silver (50-59 points) Certified (40-49 points)

  • Listing ID: 37793165

  • Date on Market: 9/23/2025

  • Last Updated:

  • Address: 35 Gatehouse Dr, Waltham, MA 02451

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