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425 Eccles Ave
South San Francisco, CA 94080
Property For Lease

Highlights

  • Move-in ready lab environment with existing casework, chemical fume hoods, and dedicated backup power.
  • Walkable access to Caltrain with rapid reach to Highway 101, 380, and 280, plus convenient ferry and airport connections.
  • Freestanding control and identity near Oyster Point’s leading life science campuses and employers.
  • Functional layout with multiple collaboration areas, amenity lounge, and efficient shipping, receiving, and storage.

Property Overview

The location delivers immediate connectivity to Highway 101, with quick links to Highway 380 and 280. Caltrain’s South San Francisco station is walkable, the South San Francisco Ferry Terminal is nearby, and San Francisco International Airport is roughly a 10-minute drive. Downtown San Francisco is approximately 20 minutes away. The site is surrounded by nationally recognized life science campuses, including Gateway of Pacific, Kilroy Oyster Point, and Genentech, giving tenants proximity to talent, suppliers, and collaborators. As a freestanding building with on-site parking and a backup generator with ample power, 425 Eccles Avenue suits single-tenant occupancy or can be configured for multiple users seeking efficient lab and office space in a premier Bay Area innovation market.

Property Facts

Property Type Flex
Property Subtype Flex Research & Development
Building Class B
Rentable Building Area 22,796 SF
Year Built/Renovated 1975/2018

Features and Amenities

  • Bio-Tech/ Lab Space
  • Wet Lab
  • Air Conditioning
  • Listing ID: 39290788

  • Date on Market: 2/2/2026

  • Last Updated:

  • Address: 425 Eccles Ave, South San Francisco, CA 94080

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