4900 Main St
Downers Grove, IL 60515
Main Street Commercial Building · Property For Lease

Main Street Commercial Building For Lease with Parking – Downtown Downers Grove Well-established medical or commercial office building available for lease in the heart of Downers Grove. This highly visible downtown location on Main Street offers building signage opportunities at the intersection of Main and Franklin Streets. Conveniently located less than two miles south of Good Samaritan Hospital, the property provides approximately 26 dedicated parking spaces, including spaces behind the building and additional parking across Main Street. The building features a functional medical layout with 18 clinical rooms (each with plumbing), lab space, nurses’ stations, a waiting room, private offices, meeting room, break room, open office space, and multiple storage areas. Please refer to the attached floor plan for full details. Building zoning listed as DB (Downtown Business) and non-medical uses considered. The space is expected to be available in January 2026, though availability is subject to change without notice.