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Retail 525 Vine St 2,503 - 51,968 SF of 5-Star Office Space Available in Winston-Salem, NC 27101

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HIGHLIGHTS

  • One of the fastest-growing urban innovation districts in the United States
  • Adjacent to Bailey Park and home to Wake Forest Medical School
  • Reception and security services

ALL AVAILABLE SPACES(6)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • Ground, Ste 130
  • 7,676 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now

Move-in ready office space! This suite is ±7,676 SF and features a lobby/reception area, IT room, large open workspace with cubicles, 7 private offices, conference room, 2 meeting rooms, break room/kitchenette, and an exterior entrance to the rear of the building. Located on the first floor, right off the elevator lobby, and the downstairs atrium.

  • Mostly Open Floor Plan Layout
  • 9 Private Offices
  • Ground, Ste 140
  • 2,503 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Conveniently located on the first floor, this ±2,503 SF office suite features a functional layout that includes private offices, a conference room, and an open work area. Large windows provide abundant natural light throughout the space, creating a bright and comfortable work environment. Ideal for a variety of professional uses, the layout supports both privacy and collaboration in a highly desirable location!

  • Fully Built-Out as Standard Office
  • 3 Private Offices
  • 6 Workstations
  • Mostly Open Floor Plan Layout
  • 2 Conference Rooms
  • 2nd Floor, Ste 155
  • 10,060 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Located on the 2nd floor and facing Vine Street, this suite has its own entrance from the courtyard, as well as the interior hallway. The suite is ±10,060 SF and features a lobby/reception area, 2 restrooms/locker rooms, high ceilings, 1 room with hardwood floors, large windows, and specialized rubber gym flooring throughout the main area. Previously housed the downtown branch of YMCA.

  • Fully Built-Out as Standard Office
  • Natural Light
  • Mostly Open Floor Plan Layout
  • Office or Retail use
  • 2nd Floor, Ste 240
  • 5,383 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

This exceptional second-floor space offers a rare opportunity for companies seeking a professional environment designed to support innovation and productivity. Featuring a large lab area and expansive office, the layout is both functional and adaptable making it ideal for research and professional uses. There are multiple entrances and direct access to the outside which enhance convenience and functionality.

  • Mostly Open Floor Plan Layout
  • 3rd Floor, Ste 320
  • 11,533 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Partial Build-Out
  • Now

This is a sleek, modern workspace that would work for a multitude of businesses. The suite is ±11,533 SF and features tons of open work area, high ceilings, lots of natural light, several private offices, storage areas, glass conference room, sound studio, photography studio, and even a theater. Has a great view of downtown and the ultra-cool atrium. Located on the 3rd floor.

  • Partially Built-Out as Standard Office
  • Natural Light
  • Open Floor Plan Layout
  • 3rd Floor, Ste 340
  • 14,813 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Located on the 3rd floor with fantastic views of downtown! This suite is ±14,813 SF and has windows and views on 3 sides of the space. It features a modern esthetic with concrete floors, high ceilings, modern wood panels, glass walls, and neutral carpeting. The suite consists of a sleek entrance/reception area, large open workspaces, several meeting rooms and private offices, 2 conference rooms, a break room/kitchenette, and ample storage.

  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout
Space Size Term Rental Rate Space Use Condition Available
Ground, Ste 130 7,676 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office - Now
Ground, Ste 140 2,503 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
2nd Floor, Ste 155 10,060 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
2nd Floor, Ste 240 5,383 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
3rd Floor, Ste 320 11,533 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Partial Build-Out Now
3rd Floor, Ste 340 14,813 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now

Ground, Ste 130

Size
7,676 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
-
Available
Now

Ground, Ste 140

Size
2,503 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 155

Size
10,060 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 240

Size
5,383 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
Full Build-Out
Available
Now

3rd Floor, Ste 320

Size
11,533 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
Partial Build-Out
Available
Now

3rd Floor, Ste 340

Size
14,813 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Condition
Full Build-Out
Available
Now

Ground, Ste 130

Size 7,676 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition -
Available Now

Move-in ready office space! This suite is ±7,676 SF and features a lobby/reception area, IT room, large open workspace with cubicles, 7 private offices, conference room, 2 meeting rooms, break room/kitchenette, and an exterior entrance to the rear of the building. Located on the first floor, right off the elevator lobby, and the downstairs atrium.

  • Mostly Open Floor Plan Layout
  • 9 Private Offices

Ground, Ste 140

Size 2,503 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition Full Build-Out
Available Now

Conveniently located on the first floor, this ±2,503 SF office suite features a functional layout that includes private offices, a conference room, and an open work area. Large windows provide abundant natural light throughout the space, creating a bright and comfortable work environment. Ideal for a variety of professional uses, the layout supports both privacy and collaboration in a highly desirable location!

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • 3 Private Offices
  • 2 Conference Rooms
  • 6 Workstations

2nd Floor, Ste 155

Size 10,060 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition Full Build-Out
Available Now

Located on the 2nd floor and facing Vine Street, this suite has its own entrance from the courtyard, as well as the interior hallway. The suite is ±10,060 SF and features a lobby/reception area, 2 restrooms/locker rooms, high ceilings, 1 room with hardwood floors, large windows, and specialized rubber gym flooring throughout the main area. Previously housed the downtown branch of YMCA.

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Natural Light
  • Office or Retail use

2nd Floor, Ste 240

Size 5,383 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition Full Build-Out
Available Now

This exceptional second-floor space offers a rare opportunity for companies seeking a professional environment designed to support innovation and productivity. Featuring a large lab area and expansive office, the layout is both functional and adaptable making it ideal for research and professional uses. There are multiple entrances and direct access to the outside which enhance convenience and functionality.

  • Mostly Open Floor Plan Layout

3rd Floor, Ste 320

Size 11,533 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition Partial Build-Out
Available Now

This is a sleek, modern workspace that would work for a multitude of businesses. The suite is ±11,533 SF and features tons of open work area, high ceilings, lots of natural light, several private offices, storage areas, glass conference room, sound studio, photography studio, and even a theater. Has a great view of downtown and the ultra-cool atrium. Located on the 3rd floor.

  • Partially Built-Out as Standard Office
  • Open Floor Plan Layout
  • Natural Light

3rd Floor, Ste 340

Size 14,813 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Condition Full Build-Out
Available Now

Located on the 3rd floor with fantastic views of downtown! This suite is ±14,813 SF and has windows and views on 3 sides of the space. It features a modern esthetic with concrete floors, high ceilings, modern wood panels, glass walls, and neutral carpeting. The suite consists of a sleek entrance/reception area, large open workspaces, several meeting rooms and private offices, 2 conference rooms, a break room/kitchenette, and ample storage.

  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout

PROPERTY OVERVIEW

Great opportunity to join one of the fastest-growing urban innovation districts in the United States. This A+ building offers reception and security services, fantastic views of downtown Winston-Salem, and an amazing architectural presence. Adjacent to Bailey Park and home to Wake Forest Medical School, health sciences, and other biotech companies.

PROPERTY FACTS

Building Type
Office
Year Built
2013
LoopNet Rating
5 Star
Building Height
4 Stories
Building Size
234,000 SF
Building Class
A
Typical Floor Size
58,500 SF
Parking
100 Surface Parking Spaces
Walk Score®
Very Walkable (71)
Bike Score®
Very Bikeable (71)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®
  • Listing ID: 23642125

  • Date on Market: 8/19/2025

  • Last Updated:

  • Address: 525 Vine St, Winston-Salem, NC 27101

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