Share This Listing

Message

940 characters remaining

Hmm, there seems to have been an error sending your message. Please try again.

Your email has been sent.

Still interested?

Contact the broker for more information about this property

Highlights

  • Historic building 6 blocks from the US Capitol
  • See brochures below for layout possibilities.

All Available Spaces(3)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste 120
  • 994 SF
  • 3 Years
  • $48.00 /SF/YR $4.00 /SF/MO $47,712 /YR $3,976 /MO
  • Retail
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • 2nd Floor, Ste 230
  • 2,980 SF
  • 3-5 Years
  • $52.00 /SF/YR $4.33 /SF/MO $154,960 /YR $12,913 /MO
  • Office
  • Full Build-Out
  • Now

This space is Plug and Play, ready to go and has a card reader to badge in, no need to fumble for keys.

  • Rate includes utilities, building services and property expenses
  • 15 Private Offices
  • 4 Workstations
  • Plug & Play
  • Kitchen
  • After Hours HVAC Available
  • Fully Built-Out as Standard Office
  • 1 Conference Room
  • Finished Ceilings: 8’2”
  • Central Air and Heating
  • Natural Light
  • Shower Facilities
  • 3rd Floor, Ste 330-340
  • 1,131-2,457 SF
  • 3 Years
  • $52.00 /SF/YR $4.33 /SF/MO $127,764 /YR $10,647 /MO
  • Office/Medical
  • -
  • April 20, 2026
  • Rate includes utilities, building services and property expenses
  • Space is in Excellent Condition
  • Private Restrooms
  • 1 Conference Room
  • Reception Area
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste 120 994 SF 3 Years $48.00 /SF/YR $4.00 /SF/MO $47,712 /YR $3,976 /MO Retail Full Build-Out Now
2nd Floor, Ste 230 2,980 SF 3-5 Years $52.00 /SF/YR $4.33 /SF/MO $154,960 /YR $12,913 /MO Office Full Build-Out Now
3rd Floor, Ste 330-340 1,131-2,457 SF 3 Years $52.00 /SF/YR $4.33 /SF/MO $127,764 /YR $10,647 /MO Office/Medical - April 20, 2026

1st Floor, Ste 120

Size
994 SF
Term
3 Years
Rental Rate
$48.00 /SF/YR $4.00 /SF/MO $47,712 /YR $3,976 /MO
Space Use
Retail
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 230

Size
2,980 SF
Term
3-5 Years
Rental Rate
$52.00 /SF/YR $4.33 /SF/MO $154,960 /YR $12,913 /MO
Space Use
Office
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 330-340

Size
1,131-2,457 SF
Term
3 Years
Rental Rate
$52.00 /SF/YR $4.33 /SF/MO $127,764 /YR $10,647 /MO
Space Use
Office/Medical
Build-Out
-
Available
April 20, 2026

1st Floor, Ste 120

Size 994 SF
Term 3 Years
Rental Rate $48.00 /SF/YR
Space Use Retail
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services

2nd Floor, Ste 230

Size 2,980 SF
Term 3-5 Years
Rental Rate $52.00 /SF/YR
Space Use Office
Build-Out Full Build-Out
Available Now

This space is Plug and Play, ready to go and has a card reader to badge in, no need to fumble for keys.

  • Rate includes utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • 15 Private Offices
  • 1 Conference Room
  • 4 Workstations
  • Finished Ceilings: 8’2”
  • Plug & Play
  • Central Air and Heating
  • Kitchen
  • Natural Light
  • After Hours HVAC Available
  • Shower Facilities

3rd Floor, Ste 330-340

Size 1,131-2,457 SF
Term 3 Years
Rental Rate $52.00 /SF/YR
Space Use Office/Medical
Build-Out -
Available April 20, 2026

  • Rate includes utilities, building services and property expenses
  • 1 Conference Room
  • Space is in Excellent Condition
  • Reception Area
  • Private Restrooms

Property Overview

650 Pennsylvania Avenue SE is a historic medical and professional office building in the heart of Capitol Hill, formerly home to the iconic Penn Theatre. Featuring preserved Art Deco architecture and modern interiors, the Penn Medical Building offers turnkey and customizable suites ideal for medical, wellness, or general office use. Current availabilities range from ±994 SF to ±4,300 SF with full build-outs, natural light, in-suite HVAC, and shared amenities. Located just steps from Eastern Market Metro, this property benefits from strong foot traffic, nearby retail and dining, and excellent visibility along Pennsylvania Avenue. Lease rates are full-service and include utilities and operating expenses.

  • Signage
  • Balcony

Property Facts

Building Type
Office
Year Built
1985
Building Height
4 Stories
Building Size
56,318 SF
Building Class
B
Typical Floor Size
11,000 SF
Unfinished Ceiling Height
11’
Parking
Surface Parking
Covered Parking at $195/month
Exceptionally walkable
100/100
Moderately drivable
70/100
Exceptional public transit
100/100
Exceptionally bikeable
90/100
  • Listing ID: 3991444

  • Date on Market: 3/31/2026

  • Last Updated:

  • Address: 650 Pennsylvania Ave SE, Washington, DC 20003

Contact the Leasing Agent

Penn Medical | 650 Pennsylvania Ave SE

What's your inquiry about?*

Select at least one of the options above

Preferred Date*

Select one date

How much space do you need? (optional)

Select size

Message* (optional)

Message is required

{{getContactFormMessageFieldCharacterCount()}} out of 600

Already a member? Log In

First Name*

Last Name*

Email*

Email address is required

Phone*

Ext (optional)

Company (optional)

New to LoopNet? No problem. We'll automatically create a free account for you. By clicking the button, you agree to LoopNet's Terms of Use and Privacy Notice.

Hmm, there seems to have been an error sending your message. Please refresh the page and try again.

Your message has been sent.
Link copied
Your LoopNet account has been created!

Please Share Your Feedback

We welcome any feedback on how we can improve LoopNet to better serve your needs.
X
{{ getErrorText(feedbackForm.starRating, "rating") }}
255 character limit ({{ remainingChars() }} charactercharacters remainingover)
{{ getErrorText(feedbackForm.msg, "rating") }}
{{ getErrorText(feedbackForm.fname, "first name") }}
{{ getErrorText(feedbackForm.lname, "last name") }}
{{ getErrorText(feedbackForm.phone, "phone number") }}
{{ getErrorText(feedbackForm.phonex, "phone extension") }}
{{ getErrorText(feedbackForm.email, "email address") }}