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Highlights

  • Discover Biltmore Medical Mall, a 152,600-square-foot Class A outpatient destination designed for leading healthcare providers.
  • Enjoy unmatched convenience with a 5/1,000 parking ratio along the premier Camelback Corridor, less than 1 mile from SR-51 and Biltmore Fashion Park.
  • Tap high-income patient groups as households within a 3-mile radius make $113,000 and spend a combined $2.3 billion annually.
  • Benefit from two on-site ambulatory surgery centers, on-site management, and a shared conference facility that enhances operational efficiency.
  • 2222 E Highland Avenue offers quick access to Downtown Phoenix plus abundant nearby dining, shopping, lodging, and services.
  • Located near Phoenix Children’s Hospital, Banner University Medical Center, and St. Joseph’s Hospital in key medical hubs.

All Available Spaces(4)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor, Ste 200
  • 3,440 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Biltmore Medical Mall offers premier Class A medical and office space in one of Phoenix’s most prestigious business districts. Located in the Camelback Corridor and steps from the Biltmore area, the property delivers an exceptional environment for healthcare providers and professional organizations. Its proximity to State Route 51 ensures optimal regional access, while the surrounding neighborhood offers a dynamic mix of fine dining, shopping, and hospitality options.

  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Smoke Detector
  • Mostly Open Floor Plan Layout
  • Central Air Conditioning
  • Prestigious Camelback Corridor location
  • 2nd Floor, Ste 220
  • 5,228 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • -
  • Now
  • Mostly Open Floor Plan Layout
  • Smoke Detector
  • Can be combined with additional space(s) for up to 6,995 SF of adjacent space
  • 2nd Floor, Ste 221
  • 1,767 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
  • Mostly Open Floor Plan Layout
  • Smoke Detector
  • Can be combined with additional space(s) for up to 6,995 SF of adjacent space
  • 3rd Floor, Ste 318
  • 2,753 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Biltmore Medical Mall is a four-story Class A office and medical complex located at 2222 E Highland Avenue in Phoenix, Arizona. The building, totaling approximately 152,600 square feet, was constructed in 1998 and is served by multiple parking options, including both covered and surface spaces. Accessibility is enhanced by direct connections to State Route 51 and its position within the Camelback Corridor, a key commercial district in Phoenix. Nearby, there is a strong concentration of healthcare providers, as well as numerous retail, dining, and hospitality venues. The property is configured to accommodate medical operations, with suites offering full build-outs and infrastructure supporting clinical requirements.

  • Listed rate may not include certain utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • Central Air Conditioning
  • Ample parking with 787 covered spaces
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Smoke Detector
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor, Ste 200 3,440 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
2nd Floor, Ste 220 5,228 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical - Now
2nd Floor, Ste 221 1,767 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
3rd Floor, Ste 318 2,753 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

2nd Floor, Ste 200

Size
3,440 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 220

Size
5,228 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
-
Available
Now

2nd Floor, Ste 221

Size
1,767 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

3rd Floor, Ste 318

Size
2,753 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 200

Size 3,440 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Biltmore Medical Mall offers premier Class A medical and office space in one of Phoenix’s most prestigious business districts. Located in the Camelback Corridor and steps from the Biltmore area, the property delivers an exceptional environment for healthcare providers and professional organizations. Its proximity to State Route 51 ensures optimal regional access, while the surrounding neighborhood offers a dynamic mix of fine dining, shopping, and hospitality options.

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Central Air Conditioning
  • Smoke Detector
  • Prestigious Camelback Corridor location

2nd Floor, Ste 220

Size 5,228 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out -
Available Now

  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 6,995 SF of adjacent space
  • Smoke Detector

2nd Floor, Ste 221

Size 1,767 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 6,995 SF of adjacent space
  • Smoke Detector

3rd Floor, Ste 318

Size 2,753 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Biltmore Medical Mall is a four-story Class A office and medical complex located at 2222 E Highland Avenue in Phoenix, Arizona. The building, totaling approximately 152,600 square feet, was constructed in 1998 and is served by multiple parking options, including both covered and surface spaces. Accessibility is enhanced by direct connections to State Route 51 and its position within the Camelback Corridor, a key commercial district in Phoenix. Nearby, there is a strong concentration of healthcare providers, as well as numerous retail, dining, and hospitality venues. The property is configured to accommodate medical operations, with suites offering full build-outs and infrastructure supporting clinical requirements.

  • Listed rate may not include certain utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Central Air Conditioning
  • Smoke Detector
  • Ample parking with 787 covered spaces

Property Overview

Discover the prime location of Biltmore Medical Mall at 2222 E Highland Avenue in Phoenix, Arizona, centrally situated in the premier Camelback Corridor. Spanning 152,600 square feet, this Class A outpatient medical building offers exceptional facilities, including two on-site ambulatory surgery centers and a common area conference/meeting room. The robust infrastructure makes the property ideal for a wide range of disciplines, such as dental, physical therapy, lab services, oncology, pediatrics, primary care, and more. With a parking ratio of 5/1,000 and direct access parking on the first and second floors, accessibility is unmatched. Conveniently located less than 1 mile from the SR-51 and Biltmore Fashion Park, patients and staff can enjoy many nearby restaurants and amenities. Notably, Biltmore Medical Mall stands as the only Class A medical office in the esteemed Biltmore Proper area. 2222 E Highland Avenue offers easy access to Downtown Phoenix and is minutes away from a wide range of restaurants, shopping, and hotels. It is also within 13 minutes of Interstate 10 and market-leasing medical hubs, including Phoenix Children’s Hospital, Banner University Medical Center, and Dignity Health St. Joseph’s Hospital. Situated adjacent to affluent Biltmore and Arcadia housing markets, Biltmore Medical Mall is the epitome of a prime healthcare destination. About Remedy: Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

  • Bus Line
  • Conferencing Facility
  • Property Manager on Site
  • Signage
  • Skyway
  • Monument Signage
  • Air Conditioning

Property Facts

Building Type
Office
Year Built
1998
LoopNet Rating
4 Star
Building Height
4 Stories
Building Size
159,745 SF
Building Class
A
Typical Floor Size
39,936 SF
Unfinished Ceiling Height
10’
Parking
50 Surface Parking Spaces
787 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • Multiple
  • Arizona Center For Cancer Care
  • Health Care and Social Assistance
  • 2nd
  • Arizona Digestive Health
  • Health Care and Social Assistance
  • 1st
  • Banner Health
  • Health Care and Social Assistance
  • 1st
  • Eye Surgery Center
  • Health Care and Social Assistance
  • 4th
  • SW Diag Imaging
  • Health Care and Social Assistance
Moderately walkable
70/100
Very drivable
80/100
Some public transit
40/100
Moderately bikeable
70/100
  • Listing ID: 28461297

  • Date on Market: 6/3/2026

  • Last Updated:

  • Address: 2222 E Highland Ave, Phoenix, AZ 85016

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