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4221-4225 Mission St 757 SF of Retail Space Available in San Francisco, CA 94112

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ALL AVAILABLE SPACE(1)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor
  • 757 SF
  • Negotiable
  • $2.55 /SF/YR $0.21 /SF/MO $1,930 /YR $160.86 /MO
  • Retail
  • -
  • Now

Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Francisco’s most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses

  • Listed rate may not include certain utilities, building services and property expenses
Space Size Term Rental Rate Space Use Condition Available
1st Floor 757 SF Negotiable $2.55 /SF/YR $0.21 /SF/MO $1,930 /YR $160.86 /MO Retail - Now

1st Floor

Size
757 SF
Term
Negotiable
Rental Rate
$2.55 /SF/YR $0.21 /SF/MO $1,930 /YR $160.86 /MO
Space Use
Retail
Condition
-
Available
Now

1st Floor

Size 757 SF
Term Negotiable
Rental Rate $2.55 /SF/YR
Space Use Retail
Condition -
Available Now

Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Francisco’s most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses

  • Listed rate may not include certain utilities, building services and property expenses

PROPERTY FACTS

Total Space Available 757 SF
No. Units 1
Property Type Multifamily
Property Subtype Apartment
Building Size 22,032 SF
Year Built 1977

ABOUT THE PROPERTY

Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Francisco’s most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses

Walk Score®
Walker's Paradise (90)
Transit Score®
Excellent Transit (83)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®

NEARBY MAJOR RETAILERS

Chase Bank
Citi
U.S. Bank
Bank of America
CrossFit
Safeway
Club Pilates
Starbucks
  • Listing ID: 39085383

  • Date on Market: 1/14/2026

  • Last Updated:

  • Address: 4221-4225 Mission St, San Francisco, CA 94112

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