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East Grand Avenue South San Francisco, CA 94080 22,250 - 59,782 SF of Flex Space Available

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PARK HIGHLIGHTS

  • Robust on-campus amenities: restaurant, conferencing center, & fitness center.
  • Ample EV charging stations
  • 15 min walk to S. SF Caltrain station
  • Generous outdoor space including on-campus walking -trails.
  • Prominent location close to Highway 101 interchange

PARK FACTS

Total Space Available 59,782 SF
Park Type Office Park

ALL AVAILABLE SPACES(2)

Display Rental Rate as

East Grand Avenue
269 E Grand Ave - Building 2
22,250 - 59,782 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/A
Year Built
2014
Building Size
111,038 SF
Building Height
3 Stories
Typical Floor Size
34,205 SF
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor
  • 22,250 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Spec Suite
  • September 01, 2026

Lab build out

  • The office offers large, open floorplates for flex
  • The building includes an Activated Wellness Center
  • Guests gather in the Amenity Hub Atrium for work.
  • 3rd Floor
  • 37,532 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Spec Suite
  • September 01, 2026

Office build out

  • The office offers large, open floorplates for flex
  • The building includes an Activated Wellness Center
  • Guests gather in the Amenity Hub Atrium for work.
Space Size Term Rental Rate Space Use Condition Available
2nd Floor 22,250 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Spec Suite September 01, 2026
3rd Floor 37,532 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Spec Suite September 01, 2026
East Grand Avenue
269 E Grand Ave - Building 2
22,250 - 59,782 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Office/A
Year Built
2014
Building Size
111,038 SF
Building Height
3 Stories
Typical Floor Size
34,205 SF

269 E Grand Ave - 2nd Floor

Size
22,250 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Spec Suite
Available
September 01, 2026

269 E Grand Ave - 3rd Floor

Size
37,532 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Spec Suite
Available
September 01, 2026

269 E Grand Ave - 2nd Floor

Size 22,250 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Condition Spec Suite
Available September 01, 2026

Lab build out

  • The office offers large, open floorplates for flex
  • Guests gather in the Amenity Hub Atrium for work.
  • The building includes an Activated Wellness Center

269 E Grand Ave - 3rd Floor

Size 37,532 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Condition Spec Suite
Available September 01, 2026

Office build out

  • The office offers large, open floorplates for flex
  • Guests gather in the Amenity Hub Atrium for work.
  • The building includes an Activated Wellness Center

SELECT TENANTS AT THIS PROPERTY

  • FLOOR
  • TENANT NAME
  • INDUSTRY
  • 1st
  • Bright Horizons
  • Health Care and Social Assistance
  • Multiple
  • Insitro, Inc.
  • Manufacturing
  • Multiple
  • Merck
  • Manufacturing
  • 3rd
  • Molecular Stethoscope
  • Information
  • Multiple
  • Verily
  • Professional, Scientific, and Technical Services

PARK OVERVIEW

SOUTH SAN FRANCISCO EAST GRAND CAMPUS: PREMIER LIFE SCIENCE CAMPUS Totaling ±620,000 Square Feet

  • Listing ID: 37277544

  • Date on Market: 8/14/2025

  • Last Updated:

  • Address: 249 E Grand Ave, South San Francisco, CA 94080

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