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Highlights

  • Located within McKinney’s established medical corridor offering superior referral connectivity.
  • Purpose-built suites designed for clinical use, incorporating exam rooms and medical-grade specifications.
  • Ample surface parking enhances patient and staff convenience.
  • Excellent visibility and access to U.S. Highway 75 and State Highway 121.
  • Generator backup and building systems optimized for healthcare tenants.
  • Surrounded by a robust network of hospitals, specialists, and wellness providers.

All Available Spaces(2)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor, Ste 270
  • 1,724 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

McKinney Medical Arts offers a premier medical office opportunity in one of North Texas’s most dynamic healthcare corridors. Located in McKinney, a fast-growing suburban market in the Dallas-Fort Worth metroplex, this property provides exceptional accessibility to US Highway 75 and SH 121. The building is purpose-built for medical use, featuring plumbed exam rooms, HVAC systems supporting medical workflows, and generator backup for operational reliability. Surrounded by major hospitals and specialty care centers, including Medical City McKinney, tenants benefit from direct proximity to established healthcare systems and a strong referral base. With suites ranging from ±1,724 SF to ±2,929 SF, practices can take advantage of turnkey medical layouts that reduce setup time and costs. This location ensures convenience for patients and medical staff alike, with ample surface parking and quick access to major arterial streets across Collin County. Positioned in a high-growth area with strong demographics and rising healthcare demand, McKinney Medical Arts provides the connectivity and infrastructure that medical professionals require for sustainable occupancy.

  • Fully Built-Out as Standard Medical Space
  • Fits 5 - 14 People
  • Private Restrooms
  • Plumbed exam rooms and medical-specific buildout
  • Building systems include HVAC and backup generator
  • Mostly Open Floor Plan Layout
  • Central Air Conditioning
  • After Hours HVAC Available
  • Convenient access to US-75 and SH 121
  • 2nd Floor, Ste 290
  • 2,929 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

McKinney Medical Arts offers a premier medical office opportunity in one of North Texas’s most dynamic healthcare corridors. Located in McKinney, a fast-growing suburban market in the Dallas-Fort Worth metroplex, this property provides exceptional accessibility to US Highway 75 and SH 121. The building is purpose-built for medical use, featuring plumbed exam rooms, HVAC systems supporting medical workflows, and generator backup for operational reliability. Surrounded by major hospitals and specialty care centers, including Medical City McKinney, tenants benefit from direct proximity to established healthcare systems and a strong referral base. With suites ranging from ±1,724 SF to ±2,929 SF, practices can take advantage of turnkey medical layouts that reduce setup time and costs. This location ensures convenience for patients and medical staff alike, with ample surface parking and quick access to major arterial streets across Collin County. Positioned in a high-growth area with strong demographics and rising healthcare demand, McKinney Medical Arts provides the connectivity and infrastructure that medical professionals require for sustainable occupancy.

  • Fully Built-Out as Standard Medical Space
  • Fits 8 - 24 People
  • Private Restrooms
  • Plumbed exam rooms and medical-specific buildout
  • Building systems include HVAC and backup generator
  • Mostly Open Floor Plan Layout
  • Central Air Conditioning
  • After Hours HVAC Available
  • Convenient access to US-75 and SH 121
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor, Ste 270 1,724 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
2nd Floor, Ste 290 2,929 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

2nd Floor, Ste 270

Size
1,724 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 290

Size
2,929 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

2nd Floor, Ste 270

Size 1,724 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

McKinney Medical Arts offers a premier medical office opportunity in one of North Texas’s most dynamic healthcare corridors. Located in McKinney, a fast-growing suburban market in the Dallas-Fort Worth metroplex, this property provides exceptional accessibility to US Highway 75 and SH 121. The building is purpose-built for medical use, featuring plumbed exam rooms, HVAC systems supporting medical workflows, and generator backup for operational reliability. Surrounded by major hospitals and specialty care centers, including Medical City McKinney, tenants benefit from direct proximity to established healthcare systems and a strong referral base. With suites ranging from ±1,724 SF to ±2,929 SF, practices can take advantage of turnkey medical layouts that reduce setup time and costs. This location ensures convenience for patients and medical staff alike, with ample surface parking and quick access to major arterial streets across Collin County. Positioned in a high-growth area with strong demographics and rising healthcare demand, McKinney Medical Arts provides the connectivity and infrastructure that medical professionals require for sustainable occupancy.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 5 - 14 People
  • Central Air Conditioning
  • Private Restrooms
  • After Hours HVAC Available
  • Plumbed exam rooms and medical-specific buildout
  • Convenient access to US-75 and SH 121
  • Building systems include HVAC and backup generator

2nd Floor, Ste 290

Size 2,929 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

McKinney Medical Arts offers a premier medical office opportunity in one of North Texas’s most dynamic healthcare corridors. Located in McKinney, a fast-growing suburban market in the Dallas-Fort Worth metroplex, this property provides exceptional accessibility to US Highway 75 and SH 121. The building is purpose-built for medical use, featuring plumbed exam rooms, HVAC systems supporting medical workflows, and generator backup for operational reliability. Surrounded by major hospitals and specialty care centers, including Medical City McKinney, tenants benefit from direct proximity to established healthcare systems and a strong referral base. With suites ranging from ±1,724 SF to ±2,929 SF, practices can take advantage of turnkey medical layouts that reduce setup time and costs. This location ensures convenience for patients and medical staff alike, with ample surface parking and quick access to major arterial streets across Collin County. Positioned in a high-growth area with strong demographics and rising healthcare demand, McKinney Medical Arts provides the connectivity and infrastructure that medical professionals require for sustainable occupancy.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Fits 8 - 24 People
  • Central Air Conditioning
  • Private Restrooms
  • After Hours HVAC Available
  • Plumbed exam rooms and medical-specific buildout
  • Convenient access to US-75 and SH 121
  • Building systems include HVAC and backup generator

Property Overview

The property at 4201 Medical Center Drive is located in McKinney, TX, within Collin County’s healthcare district. It offers connectivity to major thoroughfares including U.S. Highway 75 and State Highway 121. Nearby infrastructure includes Medical City McKinney hospital, outpatient facilities, and specialty clinics. The surrounding market features a high concentration of healthcare providers and growing regional demand for medical services.

Property Facts

Building Type
Office
Year Built
2006
Building Height
3 Stories
Building Size
58,500 SF
Building Class
B
Typical Floor Size
18,634 SF
Parking
Surface Parking

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 2nd
  • Avicenna Vascular Institute
  • -
  • 3rd
  • Cardiac Center Of Texas Pa
  • Health Care and Social Assistance
  • 2nd
  • Hearing Services Of Mckinney
  • Health Care and Social Assistance
  • 2nd
  • Innova Psychiatric Group
  • Health Care and Social Assistance
  • Unknown
  • Labcorp
  • Health Care and Social Assistance
  • 2nd
  • McKinney Spine & Pain Center
  • -
  • 1st
  • Solis Mammography
  • Health Care and Social Assistance
  • 2nd
  • StrideCare
  • Health Care and Social Assistance
  • 1st
  • The Center For Cancer & Blood Disorders
  • Health Care and Social Assistance
  • 3rd
  • Vein Clinic Of Texas
  • -
Fairly walkable
40/100
Exceptionally drivable
100/100
Somewhat bikeable
30/100
  • Listing ID: 40925257

  • Date on Market: 6/15/2026

  • Last Updated:

  • Address: 4201 Medical Center Dr, McKinney, TX 75069

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